{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T18:54:10Z","timestamp":1649184850241},"reference-count":12,"publisher":"Georg Thieme Verlag KG","issue":"01\/02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dtsch Med Wochenschr"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Anamnese\u2002Eine 35-j\u00e4hrige Patientin stellte sich mit akuten starken Kopfschmerzen, Photophobie und Fieber vor. Mehrere Mitglieder der Familie der Patientin litten vorg\u00e4ngig an der Hand-Mund-Fu\u00df-Krankheit.<\/jats:p><jats:p>\n          Status und Befunde\u2002Klinisch fiel ein prominenter Meningismus auf. Lumbalpunktion und kraniales Computertomogramm waren unauff\u00e4llig. Im weiteren Verlauf fiel die PCR-Untersuchung des Liquors positiv f\u00fcr Enteroviren-Spezies-RNA aus.<\/jats:p><jats:p>\n          Diagnose und Therapie\u2002Bei best\u00e4tigter Enteroviren-Meningitis konnte die initial verabreichte antimikrobielle Therapie sistiert und auf weiterf\u00fchrende Diagnostik verzichtet werden.<\/jats:p><jats:p>\n          Verlauf\u2002Die Symptome waren rasch und vollst\u00e4ndig regredient.<\/jats:p><jats:p>\n          Folgerungen\u2002Dieser Fall soll aufzeigen, dass bei typischer Klinik einer Meningitis ohne Liquorpleozytose die Enteroviren-Meningitis auch bei adulten Patienten eine wichtige Differenzialdiagnose darstellt.<\/jats:p>","DOI":"10.1055\/a-1666-7794","type":"journal-article","created":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T23:31:17Z","timestamp":1640734277000},"page":"43-45","source":"Crossref","is-referenced-by-count":0,"title":["Liquor klar \u2013 Diagnose (un)klar"],"prefix":"10.1055","volume":"147","author":[{"given":"Rapha\u00ebl","family":"Tam\u00f2","sequence":"additional","affiliation":[{"name":"Klinik Innere Medizin Standort Triemli, Department Innere Medizin, Stadtspital Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabeth","family":"Simons","sequence":"additional","affiliation":[{"name":"Klinik Innere Medizin Standort Triemli, Department Innere Medizin, Stadtspital Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars C.","family":"Huber","sequence":"additional","affiliation":[{"name":"Klinik Innere Medizin Standort Triemli, Department Innere Medizin, Stadtspital Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,12,28]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1136\/bmj.39409.673657.AE","article-title":"Viral meningitis","volume":"336","author":"S A Logan","year":"2008","journal-title":"Brit Med J"},{"issue":"01","key":"ref2","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1212\/01.wnl.0000191407.81333.00","article-title":"Etiology of aseptic meningitis and encephalitis in an adult population","volume":"66","author":"L Kupila","year":"2006","journal-title":"Neurology"},{"issue":"01","key":"ref3","doi-asserted-by":"publisher","first-page":"1010","DOI":"10.1186\/s12879-019-4635-6","article-title":"Meningitis gone viral: description of the echovirus wave 2013 in Germany","volume":"19","author":"J Graf","year":"2019","journal-title":"BMC Infect Dis"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.jcv.2018.04.017","article-title":"Clinical and biological features of enteroviral meningitis among adults and children and factors associated with severity and length of stay","volume":"104","author":"M Vareil","year":"2018","journal-title":"J Clin Virol"},{"issue":"10","key":"ref5","doi-asserted-by":"publisher","first-page":"874","DOI":"10.1136\/archdischild-2012-301884","article-title":"Enteroviral meningitis without pleocytosis in children","volume":"97","author":"K W Yun","year":"2012","journal-title":"Arch Dis Child"},{"issue":"05","key":"ref6","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1007\/s00431-011-1626-z","article-title":"Characteristics of pediatric patients with enterovirus meningitis and no cerebral fluid pleocytosis","volume":"171","author":"S C de Crom","year":"2012","journal-title":"Eur J Pediatr"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"bcr2014203733","DOI":"10.1136\/bcr-2014-203733","article-title":"Confirmed viral meningitis with normal CSF findings","volume":"2014","author":"N Dawood","year":"2014","journal-title":"BMJ Case Rep"},{"issue":"06","key":"ref8","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1086\/591129","article-title":"Clinical features of viral meningitis in adults: significant differences in cerebrospinal fluid findings among herpes simplex virus, varicella zoster virus, and enterovirus infections","volume":"47","author":"U K Ihekwaba","year":"2008","journal-title":"Clin Infect Dis"},{"issue":"16","key":"ref9","doi-asserted-by":"publisher","first-page":"1578","DOI":"10.1056\/NEJMcpc2004996","article-title":"Case 32-2020: A 63-Year-Old Man with Confusion, Fatigue, and Garbled Speech","volume":"383","author":"S S Mukerji","year":"2020","journal-title":"N Engl J Med"},{"issue":"09","key":"ref10","doi-asserted-by":"publisher","first-page":"992","DOI":"10.1016\/S1473-3099(18)30245-7","article-title":"Incidence, aetiology, and sequelae of viral meningitis in UK adults: a multicentre prospective observational cohort study","volume":"18","author":"UK Meningitis Study Investigators","year":"2018","journal-title":"Lancet Infect Dis"},{"issue":"03","key":"ref11","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1093\/cid\/cix319","article-title":"Epidemiology of Meningitis and Encephalitis in the United States, 2011-2014","volume":"65","author":"R Hasbun","year":"2017","journal-title":"Clin Infect Dis"},{"issue":"01","key":"ref12","doi-asserted-by":"publisher","first-page":"3","DOI":"10.2165\/00019053-200119010-00001","article-title":"Enteroviral meningitis. Cost of illness and considerations for the economic evaluation of potential therapies","volume":"19","author":"T V Parasuraman","year":"2001","journal-title":"Pharmacoeconomics"}],"container-title":["DMW - Deutsche Medizinische Wochenschrift"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1666-7794.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T23:32:31Z","timestamp":1640734351000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1666-7794"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,28]]},"references-count":12,"journal-issue":{"issue":"01\/02","published-online":{"date-parts":[[2021,12,28]]},"published-print":{"date-parts":[[2022,1]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1666-7794","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0012-0472","1439-4413"],"issn-type":[{"value":"0012-0472","type":"print"},{"value":"1439-4413","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,28]]}}}