{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,2,4]],"date-time":"2023-02-04T21:50:48Z","timestamp":1675547448849},"reference-count":43,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Monbl Augenheilkd"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Zielsetzung Darstellung der aktuellen deutschsprachigen interdisziplin\u00e4ren Leitlinie zur Diagnostik und Therapie der JIA-assoziierten Uveitis (JIA: juvenile idiopathische Arthritis)\n\t\t\t\t\tanhand von Kasuistiken.<\/jats:p><jats:p>\n          Material und Methoden Leitlinie der Deutschen Ophthalmologischen Gesellschaft, der Gesellschaft f\u00fcr Kinder- und Jugendrheumatologie, der Deutschen Gesellschaft f\u00fcr Rheumatologie, des\n\t\t\t\t\tBerufsverbandes der Augen\u00e4rzte Deutschlands unter Beteiligung von Patientenvertretern. Die unl\u00e4ngst publizierte Prim\u00e4rliteratur wurde kritisch bewertet hinsichtlich Evidenz und Empfehlungen;\n\t\t\t\t\tmethodisch wurden Konsensfindung mittels Delphi-Runden und eine externe Begutachtung einbezogen. Die Ergebnisse werden anhand von typischen Fallbeispielen erl\u00e4utert.<\/jats:p><jats:p>\n          Ergebnisse Bei JIA-Erstdiagnose sollten regelm\u00e4\u00dfige augen\u00e4rztliche Kontrollen erfolgen mit dem Ziel, dass die Uveitis vor Manifestation irreversibler Folgesch\u00e4den diagnostiziert\n\t\t\t\t\twird. Entsprechend dem individuellen Schweregrad der Uveitis kann eine qualitativ hochwertige Versorgung der Patienten erzielt werden. Zur antientz\u00fcndlichen Therapie finden aktuell\n\t\t\t\t\tKortikosteroide, konventionell synthetische (cs) und biologische (b) und andere Disease-modifying anti-rheumatic Drugs (DMARDs) Verwendung.<\/jats:p><jats:p>\n          Schlussfolgerungen Fr\u00fchzeitige Diagnose und aktuelle leitliniengerechte Therapie k\u00f6nnen die Langzeitprognose der JIA-assoziierten Uveitis wesentlich verbessern.<\/jats:p>","DOI":"10.1055\/a-1686-5158","type":"journal-article","created":{"date-parts":[[2022,3,23]],"date-time":"2022-03-23T23:56:03Z","timestamp":1648079763000},"page":"676-685","source":"Crossref","is-referenced-by-count":2,"title":["Uveitis bei juveniler idiopathischer Arthritis \u2013 leitliniengerechte Diagnostik und Therapie anhand von Kasuistiken"],"prefix":"10.1055","volume":"239","author":[{"given":"Arnd","family":"Heiligenhaus","sequence":"additional","affiliation":[{"name":"Augenzentrum am St.\u00a0Franziskus Hospital, M\u00fcnster, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Deuter","sequence":"additional","affiliation":[{"name":"Department f\u00fcr Augenheilkunde, Universit\u00e4tsklinikum T\u00fcbingen, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,3,23]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1093\/rheumatology\/kem053","article-title":"Prevalence and complications of uveitis in juvenile idiopathic arthritis in a population-based nation-wide study in Germany: suggested modification of the current screening guidelines","volume":"46","author":"A Heiligenhaus","year":"2007","journal-title":"Rheumatology"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.1016\/S0161-6420(01)00773-4","article-title":"Occurrence of uveitis in recently diagnosed juvenile chronic arthritis. 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