{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T02:33:08Z","timestamp":1777343588545,"version":"3.51.4"},"reference-count":19,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Handchir Mikrochir Plast Chir"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n                    Einleitung Die periphere Nervenstimulation (PNS) hat sich, anlehnend an die zentrale Nervenstimulation (Spinal Cord Stimulation \u2013 SCS), als geeignete Therapieoption zur Behandlung des komplexen regionalen Schmerzsyndroms (CRPS) vor allem im Bereich der oberen Extremit\u00e4t gezeigt. Die Evidenz zur PNS ist jedoch in der aktuellen Literatur sehr sp\u00e4rlich.<\/jats:p><jats:p>\n                    Material und Methoden Bei 11 Patient*innen mit CRPS2 wurden nach strengen Selektionskriterien die Implantation eines Peripheren Nervenstimulationssystems indiziert. Es handelte sich dabei um 5 M\u00e4nner und 6 Frauen im mittleren Alter von 46,4 (24\u201358) Jahren. Der mittlere Schmerzscore wurde von den Patient*innen pr\u00e4operativ mit 8,0 (\u00b11,3) auf der zehnteiligen Numerischen Rating-Skala (NRS) angegeben. Bei 8 Patient*innen wurden Elektroden an der oberen Extremit\u00e4t (Plexus brachialis), bei 2 Patient*innen im Bereich der unteren (N. ischiadicus) und bei einer Patientin sowohl an oberer als auch an unterer Extremit\u00e4t implantiert. Die 8 aktiven Elektrodenpole wurden m\u00f6glichst parallel an den Zielnerven implantiert und mittels Verl\u00e4ngerungselektroden an ein externes Stimulationsger\u00e4t angeschlossen. Nach einer Testphase von 5 Tagen wurde bei positivem Feedback und einer anhand Schmerzprotokoll ersichtlichen Schmerzreduktion von zumindest 4 Punkten auf der NRS der definitive Impulsgeber implantiert.<\/jats:p><jats:p>\n                    Ergebnisse Alle 11 Patient*innen wurden erfolgreich mit einem implantierbaren peripheren Nervenstimulationssystem der Firma Boston Scientific Inc. versorgt. Die durchschnittliche Schmerzreduktion betrug 4,6 (\u00b11,2) Punkte auf der NRS. Der durchschnittliche postoperative Schmerzwert betrug 3,4 (\u00b10,9). Der postoperative Verlauf gestaltete sich bei allen Patient*innen komplikationslos.<\/jats:p><jats:p>\n                    Schlussfolgerung Die periphere Nervenstimulation erscheint als geeignete Therapieoption zur Behandlung des CRPS 2 bei Versagen konservativer und herk\u00f6mmlicher operativer Behandlungsmethoden. Die Erfahrung an unseren Patient*innen zeigt, dass neuropathische Schmerzen erfolgreich um durchschnittlich etwa 4 Punkte auf der NRS reduziert werden konnten. Arthrogene Beschwerden hingegen zeigten sich durch die PNS unbeeinflussbar. Da es sich beim CRPS um eine psychosomatische Erkrankung handelt, ist die Einbindung der PNS in ein multimodales Therapiekonzept mit Physio- und Ergotherapie und Psychologie essenziell f\u00fcr den Behandlungserfolg.<\/jats:p>","DOI":"10.1055\/a-1687-9374","type":"journal-article","created":{"date-parts":[[2022,3,23]],"date-time":"2022-03-23T00:02:11Z","timestamp":1647993731000},"page":"131-138","source":"Crossref","is-referenced-by-count":2,"title":["Erste Erfahrungen mit der peripheren Nervenstimulation mittels implantierbarem System als Behandlungsmethode des komplexen regionalen Schmerzsyndroms CRPS 2"],"prefix":"10.1055","volume":"54","author":[{"given":"Isabelle","family":"Sawetz","sequence":"additional","affiliation":[{"name":"Medizinische Universit\u00e4t Graz; Abteilung f\u00fcr Plastische, \u00c4sthetische und Rekonstruktive Chirurgie"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Smolle","sequence":"additional","affiliation":[{"name":"Medizinische Universit\u00e4t Graz; Abteilung f\u00fcr Plastische, \u00c4sthetische und Rekonstruktive Chirurgie"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Werner","family":"Girsch","sequence":"additional","affiliation":[{"name":"Orthop\u00e4disches Spital Speising GmbH; 1. und Kinderabteilung"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,3,22]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"h2730","DOI":"10.1136\/bmj.h2730","article-title":"Complex regional pain syndrome","volume":"29","author":"S Bruehl","year":"2015","journal-title":"BMJ"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/s00393-017-0299-z","article-title":"Komplexes regionales Schmerzsyndrom","volume":"76","author":"F Brunner","year":"2017","journal-title":"Z F\u00fcr Rheumatol"},{"key":"ref3","first-page":"249","article-title":"a list with definitions and notes on usage. 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Chirurgie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1687-9374.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,14]],"date-time":"2022-04-14T04:22:37Z","timestamp":1649910157000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1687-9374"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,22]]},"references-count":19,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2022,4,13]]},"published-print":{"date-parts":[[2022,4]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1687-9374","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0722-1819","1439-3980"],"issn-type":[{"value":"0722-1819","type":"print"},{"value":"1439-3980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,22]]}}}