{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,6,11]],"date-time":"2023-06-11T13:07:30Z","timestamp":1686488850794},"reference-count":25,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Monbl Augenheilkd"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Glaukome stellen in ihrer Endstrecke eine spezifische, sich schleichend entwickelnde Neuropathie mit sp\u00e4ter fortschreitenden Gesichtsfelddefekten dar. Die Fr\u00fchdiagnose ist herausfordernd,\n\t\t\t\t\taber notwendig, da der Schaden irreparabel ist. Biomarker der strukturellen optischen Koh\u00e4renztomografie (OCT) k\u00f6nnen auf das Vorliegen einer neuronalen Atrophie hinweisen, sind jedoch in\n\t\t\t\t\tder Differenzialdiagnose zu anderen Atrophieformen nicht spezifisch. Die Kombination der OCT-Parameter miteinander und mit anderen klinischen Parametern kann die Glaukomdiagnose erleichtern.\n\t\t\t\t\tDie Anwendung von k\u00fcnstlicher Intelligenz (KI) auf OCT-Bilder k\u00f6nnte spezifischer und damit in Zukunft der reinen Schichtdickenmessung mit der OCT als Biomarker \u00fcberlegen sein.<\/jats:p>","DOI":"10.1055\/a-1688-1601","type":"journal-article","created":{"date-parts":[[2022,2,25]],"date-time":"2022-02-25T01:23:22Z","timestamp":1645752202000},"page":"149-157","source":"Crossref","is-referenced-by-count":1,"title":["Gibt es statisch-strukturelle Biomarker bei den Glaukomen mit der OCT?"],"prefix":"10.1055","volume":"239","author":[{"given":"Christian Yahya","family":"Mardin","sequence":"additional","affiliation":[{"name":"Augenklinik, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg, Erlangen, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,2,24]]},"reference":[{"key":"ref1","first-page":"639","article-title":"Principles of glaucoma diagnostics with optical coherence tomography","volume":"112","author":"C Mardin","year":"2015","journal-title":"Ophthalmologe"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1097\/IJG.0000000000000875","article-title":"Precision of optic nerve head and retinal nerve fiber layer parameter measurements by spectral-domain optical coherence tomography","volume":"27","author":"L M Schrems-Hoesl","year":"2018","journal-title":"J Glaucoma"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1706","DOI":"10.3390\/jcm9061706","article-title":"Optical coherence tomography angiography in neurodegenerative disorders","volume":"9","author":"M Pellegrini","year":"2020","journal-title":"J Clin Med"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1097\/IJG.0000000000001380","article-title":"Does ganglion cell loss precede visual field loss in glaucoma?","volume":"28","author":"D C Hood","year":"2019","journal-title":"J Glaucoma"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1097\/WNO.0000000000000768","article-title":"Macular ganglion cell and inner plexiform layer thickness is more strongly associated with visual function in multiple sclerosis than Bruch membrane opening minimum rim width or\n\t\t\t\t\tperipapillary retinal nerve fiber layer thicknesses","volume":"39","author":"J Nguyen","year":"2019","journal-title":"J Neuroophthalmol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"2141","DOI":"10.1177\/1120672121996638","article-title":"Bruch\u02bcs membrane opening-minimum rim width: an alternative OCT biomarker study for multiple sclerosis","volume":"31","author":"K T \u00d6zbilen","year":"2021","journal-title":"Eur J Ophthalmol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0039-6257(98)00049-6","article-title":"Ophthalmoscopic evaluation of the optic nerve head","volume":"43","author":"J B Jonas","year":"1999","journal-title":"Surv Ophthalmol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1167\/iovs.15-18788","article-title":"Changes in retinal nerve fiber layer reflectance intensity as a predictor of functional progression in glaucoma","volume":"57","author":"S K Gardiner","year":"2016","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"7180","DOI":"10.1167\/iovs.11-7716","article-title":"Hypodense regions (holes) in the retinal nerve fiber layer in frequency-domain OCT scans of glaucoma patients and suspects","volume":"52","author":"D Xin","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"e0130175","DOI":"10.1371\/journal.pone.0130175","article-title":"Microcystic inner nuclear layer changes and retinal nerve fiber layer defects in eyes with glaucoma","volume":"10","author":"T Hasegawa","year":"2015","journal-title":"PLoS One"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"395189","DOI":"10.1155\/2014\/395189","article-title":"Microcystic changes in the retinal internal nuclear layer associated with optic atrophy: a prospective study","volume":"2014","author":"B Wolff","year":"2014","journal-title":"J Ophthalmol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.ophtha.2013.08.018","article-title":"Defects of the lamina cribrosa in eyes with localized retinal nerve fiber layer loss","volume":"121","author":"A J Tatham","year":"2014","journal-title":"Ophthalmology"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"4478","DOI":"10.1167\/iovs.12-11268","article-title":"Comparative assessment for the ability of Cirrus, RTVue, and 3D-OCT to diagnose glaucoma","volume":"54","author":"A Akashi","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1097\/IJG.0000000000001631","article-title":"Optical Coherence Tomography Can Be Used to Assess Glaucomatous Optic Nerve Damage in Most Eyes With High Myopia","volume":"29","author":"Z Z Zemborain","year":"2020","journal-title":"J Glaucoma"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1167\/tvst.9.7.50","article-title":"Comparison of Rates of Progression of Macular OCT Measures in Glaucoma","volume":"9","author":"A Rabiolo","year":"2020","journal-title":"Transl Vis Sci Technol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1016\/j.ophtha.2019.03.003","article-title":"Measurement floors and dynamic ranges of OCT and OCT angiography in glaucoma","volume":"126","author":"S Moghimi","year":"2019","journal-title":"Ophthalmology"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1016\/j.ophtha.2017.04.023","article-title":"Ganglion cell\u2013inner plexiform layer change detected by optical coherence tomography indicates progression in advanced glaucoma","volume":"124","author":"J W Shin","year":"2017","journal-title":"Ophthalmology"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"3613","DOI":"10.1167\/iovs.12-9786","article-title":"Longitudinal analysis of progression in glaucoma using spectral-domain optical coherence tomography","volume":"54","author":"J M Wessel","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"2357","DOI":"10.1167\/iovs.17-23456","article-title":"Factors influencing central lamina cribrosa depth: a multicenter study","volume":"59","author":"H Luo","year":"2018","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1097\/ICU.0000000000000024","article-title":"Diagnosing glaucoma progression with optical coherence tomography","volume":"25","author":"C KS Leung","year":"2014","journal-title":"Curr Opin Ophthalmol"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"8844614","DOI":"10.1155\/2021\/8844614","article-title":"Optical Coherence Tomography Imaging of the Lamina Cribrosa: Structural Biomarkers in Nonglaucomatous Diseases","volume":"2021","author":"A Paulo","year":"2021","journal-title":"J Ophthalmol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1111\/aos.12809","article-title":"The choroid and lamina cribrosa is affected in patients with Parkinson\u02bcs disease: enhanced depth imaging optical coherence tomography study","volume":"94","author":"M Eraslan","year":"2016","journal-title":"Acta Ophthalmol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1167\/iovs.63.1.18","article-title":"In Vivo Sublayer Analysis of Human Retinal Inner Plexiform Layer Obtained by Visible-Light Optical Coherence Tomography","volume":"63","author":"Z Ghassabi","year":"2022","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1016\/j.ajo.2021.06.010","article-title":"Describing the Structural Phenotype of the Glaucomatous Optic Nerve Head Using Artificial Intelligence","volume":"236","author":"S K Panda","year":"2021","journal-title":"Am J Ophthalmol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"e0252339","DOI":"10.1371\/journal.pone.0252339","article-title":"Glaucoma classification based on scanning laser ophthalmoscopic images using a deep learning ensemble method","volume":"16","author":"D Su\u0142ot","year":"2021","journal-title":"PLoS One"}],"container-title":["Klinische Monatsbl\u00e4tter f\u00fcr Augenheilkunde"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1688-1601.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,25]],"date-time":"2022-02-25T01:23:49Z","timestamp":1645752229000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1688-1601"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":25,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2022,2,24]]},"published-print":{"date-parts":[[2022,2]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1688-1601","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0023-2165","1439-3999"],"issn-type":[{"value":"0023-2165","type":"print"},{"value":"1439-3999","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2]]}}}