{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T05:02:04Z","timestamp":1649048524307},"reference-count":38,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg G Grosstiere Nutztiere"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n               Gegenstand und Ziel Atemwegserkrankungen, meist multifaktoriell bedingt, f\u00fchren weltweit zu Problemen in Schweinepopulationen. Infekti\u00f6se Ursachen, wie das Porzine Circovirus Typ 2 (PCV2) und Mycoplasma hyopneumoniae (M.\u2005hyopneumoniae) k\u00f6nnen neben Management-, Haltungs- und Umweltfaktoren an der Krankheitsentstehung beteiligt sein. In einem konventionell wirtschaftenden, kombinierten Betrieb in Niedersachsen, auf dem die Ferkel nicht gegen PCV2 geimpft wurden, sollte \u00fcberpr\u00fcft werden, inwiefern die Einf\u00fchrung einer Impfung gegen PCV2 (Suvaxyn\u00ae Circo + MH RTU, Zoetis) einen Effekt auf die Tiergesundheit hat und wie die Wirkung dieses Kombinationsimpfstoffes im Vergleich zu simultan verabreichten Monoimpfstoffen gegen PCV2 und M.\u2005hyopneumoniae zu bewerten ist.<\/jats:p><jats:p>\n               Material und Methoden In einem zweiphasigen Versuch wurden 524 (Phase 1) bzw. 521 (Phase 2) klinisch gesunde Ferkel in der ersten Lebenswoche eingeschlossen. In der ersten Phase wurden Leistungsparameter bei Tieren verglichen, die nur gegen M.\u2005hyopneumoniae (Gruppe A) bzw. gegen PCV2 und M.\u2005hyopneumoniae (Gruppe B) geimpft worden waren. In Phase 2 wurden Impfungen gegen PCV2 und M.\u2005hyopneumoniae mit unterschiedlichen Impfstoffen verglichen (Gruppen C und D). Die Leistungsparameter umfassten die Verluste \u00fcber die gesamte Lebensdauer der Tiere, die t\u00e4glichen Zunahmen in der S\u00e4ugephase, Aufzucht und Mast, sowie die stichprobenartig erfasste Erregerlast im Serum (PCV2) oder im Tracheobronchialsekret (M.\u2005hyopneumoniae). Zus\u00e4tzlich wurde eine Beurteilung der Schlachtlungen durchgef\u00fchrt.<\/jats:p><jats:p>\n               Ergebnisse In der ersten Phase zeigte sich, dass die Gruppe, die die PCV2-Impfung erhalten hatte (Gruppe B: Suvaxyn\u00ae Circo + MH RTU) in den Endmast- (+ 37 g, p = 0,012) und in den t\u00e4glichen Gesamtzunahmen (+ 16 g, p = 0,013) einen signifikanten Unterschied zur Gruppe ohne PCV2-Impfung (Gruppe A) aufwies. In Gruppe A konnte signifikant h\u00e4ufiger eine PCV2-Vir\u00e4mie nachgewiesen werden. In der zweiten Phase konnte gezeigt werden, dass Gruppe D dem etablierten Impfschema von Gruppe C nicht unterlegen war. Nachweisraten f\u00fcr M.\u2005hyopneumoniae in den Tracheobronchialsekreten lagen bei Endmastschweinen in der 22. Lebenswoche gruppen\u00fcbergreifend zwischen 27\u201380 %.<\/jats:p><jats:p>\n               Schlussfolgerung Die Einf\u00fchrung einer Impfung gegen PCV2 f\u00fchrte zu einer verbesserten Tiergesundheit und zu h\u00f6heren t\u00e4glichen Zunahmen.<\/jats:p><jats:p>\n               Klinische Relevanz Mit dem hier untersuchten Kombinationsimpfstoff steht Landwirten und Tier\u00e4rzten eine weitere M\u00f6glichkeit zur Verbesserung der Tiergesundheit in der Schweinehaltung zur Verf\u00fcgung.<\/jats:p>","DOI":"10.1055\/a-1696-1578","type":"journal-article","created":{"date-parts":[[2022,3,2]],"date-time":"2022-03-02T23:42:28Z","timestamp":1646264548000},"page":"21-29","source":"Crossref","is-referenced-by-count":0,"title":["Leistungsparameter und Erregernachweise in unterschiedlich geimpften Tiergruppen in Bezug auf das Porzine Circovirus Typ 2 und Mycoplasma 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Hannover"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus","family":"Heimann","sequence":"additional","affiliation":[{"name":"Au\u00dfenstelle f\u00fcr Epidemiologie, Stiftung Tier\u00e4rztliche Hochschule Hannover"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annika","family":"K\u00f6hrmann","sequence":"additional","affiliation":[{"name":"Zoetis Deutschland GmbH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel","family":"Hennig-Pauka","sequence":"additional","affiliation":[{"name":"Au\u00dfenstelle f\u00fcr Epidemiologie, Stiftung Tier\u00e4rztliche Hochschule Hannover"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,3,2]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1151","DOI":"10.1111\/j.1939-1676.2009.0389.x","article-title":"Porcine circovirus type 2 and porcine circovirus-associated disease","volume":"23","author":"J 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