{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:33:45Z","timestamp":1740126825979,"version":"3.37.3"},"reference-count":31,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:p>\n            Objective\u2003The objective of this article was to correlate hypotension and cerebral saturation from near-infrared spectroscopy (cNIRS) in neonates on dopamine.<\/jats:p><jats:p>\n            Study Design\u2003Retrospective review of neonates receiving dopamine between August 2018 and 2019 was performed. Hypotension thresholds included mean arterial pressure (MAP) of postmenstrual age (PMA)\u2009\u00b1\u20095 and 30\u2009mm Hg and gestational age (GA)\u2009\u00b1\u20095\u2009mm Hg. Time below threshold MAP was compared with time with cerebral hypoxia (cNIRS &lt;55%).<\/jats:p><jats:p>\n            Results\u2003Hypotension occurred 6 to 33% of the time on dopamine in 59 cases. Hypotension did not correlate with abnormal cNIRS overall, within PMA subgroups or by outcomes. Hypotensive periods with MAP\u2009&lt;\u2009GA had fewer corresponding percent time with abnormal cNIRS events (3.7\u2009\u00b1\u20091.3%) compared with MAP\u2009&lt;\u2009PMA (11.9\u2009\u00b1\u20094.9%, p\u2009&lt;\u20090.003) or 30\u2009mm Hg thresholds (12.2\u2009\u00b1\u20094.7%, p\u2009&lt;\u20090.0001). In most premature infants, mean cNIRS values during hypotension were still within normal range (57\u2009\u00b1\u20096%).<\/jats:p><jats:p>\n            Conclusion\u2003cNIRS may be a more clinically relevant measure than MAP for the assessment of neonatal hypotension.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/a-1704-1851","type":"journal-article","created":{"date-parts":[[2021,11,24]],"date-time":"2021-11-24T00:02:21Z","timestamp":1637712141000},"page":"498-504","source":"Crossref","is-referenced-by-count":0,"title":["Blood Pressure Goals: Is Cerebral Saturation the New Mean Arterial Pressure?"],"prefix":"10.1055","volume":"41","author":[{"given":"Kevin J.","family":"McKim","sequence":"additional","affiliation":[{"name":"Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Lucafo","sequence":"additional","affiliation":[{"name":"Milipore Sigma, Burlington, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shazia","family":"Bhombal","sequence":"additional","affiliation":[{"name":"Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Bain","sequence":"additional","affiliation":[{"name":"Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6942-1423","authenticated-orcid":false,"given":"Valerie Y.","family":"Chock","sequence":"additional","affiliation":[{"name":"Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, 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