{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:14:16Z","timestamp":1787004856333,"version":"build-2736575974"},"reference-count":31,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg K Kleintiere Heimtiere"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Gegenstand und Ziel Die kanine Babesiose ist eine durch Dermacentor reticulatus \u00fcbertragene Infektionskrankheit, die in Deutschland an Bedeutung gewinnt. Ziel der Studie war es, das vermehrte Vorkommen der kaninen Babesiose im Rhein-Main-Gebiet in Hessen, vor allem mit Akkumulation im Kreis Gro\u00df-Gerau, zu zeigen.<\/jats:p>\n                  <jats:p>Material und Methode In die retrospektive Studie wurden Hunde aufgenommen, die im Zeitraum von Oktober 2018 bis Dezember 2020\u2005in der Tierklinik vorgestellt wurden und anhand einer positiven Babesien-PCR die Diagnose einer kaninen Babesiose erhielten.<\/jats:p>\n                  <jats:p>Ergebnisse Von den insgesamt 697 der in diesem Zeitraum durchgef\u00fchrten Babesia spp.-PCR Untersuchungen waren 81 positiv (12\u2005%). Bei 14 der 81 Babesien-positiv getesteten Hunde (17\u2005%) wurde eine Sequenzierung durchgef\u00fchrt (B. canis n\u2005=\u200513, B. vulpes n\u2005=\u20051). Zwei Hunde zeigten zeitgleich eine Anaplasmose. Auff\u00e4llig ist, dass die Babesiose-F\u00e4lle ganzj\u00e4hrig mit H\u00e4ufungen im M\u00e4rz\/April sowie im Oktober auftraten.<\/jats:p>\n                  <jats:p>In der H\u00e4matologie konnte bei 44 von 81\u2005Tieren (54\u2005%) eine Panzytopenie nachgewiesen werden. Eine An\u00e4mie lag bei 66 (82\u2005%), eine Thrombozytopenie bei 76 der 81\u2005Patienten (94\u2005%) vor. Nur bei 2 der 81\u2005F\u00e4lle konnten keine h\u00e4matologischen Ver\u00e4nderungen festgestellt werden. Eine Hyperbilirubin\u00e4mie fiel bei 66 der 73 gemessenen Bilirubinwerten (90\u2005%) auf.<\/jats:p>\n                  <jats:p>Bei allen Tieren erfolgte eine Therapie mit zweimaliger Injektion von Imidocarb-Diproprionat (Carbesia\u00ae) im Abstand von 14\u2005Tagen. Bei 37 der 81\u2005Patienten (46\u2005%) wurde eine Erfolgskontrolle mittels PCR durchgef\u00fchrt. Bei den meisten dieser Patienten (92\u2005%) konnte eine erfolgreiche Therapie durch eine negative Babesien-PCR best\u00e4tigt werden. Insgesamt 6 der 81\u2005Patienten (7\u2005%) wurden im Laufe der Behandlung eingeschl\u00e4fert. Die Gr\u00fcnde f\u00fcr die Euthanasie waren progressive Nierenerkrankung, hochgradige intravaskul\u00e4re H\u00e4molyse mit der Notwendigkeit von multiplen Bluttransfusionen sowie Bildung von Milz- und Nierenabszessen.<\/jats:p>\n                  <jats:p>Schlussfolgerung Bei Hunden mit Symptomen wie Apathie, Pyrexie und H\u00e4moglobinurie sowie h\u00e4matologischen Ver\u00e4nderungen im Sinne einer An\u00e4mie, Thrombozytopenie oder auch h\u00e4ufig einer Panzytopenie sollte eine Babesiose, unabh\u00e4ngig von der Jahreszeit, vor allem im Fr\u00fchjahr und Herbst differentialdiagnostisch ausgeschlossen werden.<\/jats:p>","DOI":"10.1055\/a-1704-6604","type":"journal-article","created":{"date-parts":[[2022,7,5]],"date-time":"2022-07-05T18:32:14Z","timestamp":1657045934000},"page":"162-172","source":"Crossref","is-referenced-by-count":10,"title":["Vorkommen von kaniner Babesiose bei Hunden im Rhein-Main-Gebiet in Hessen \u2013 eine Fallstudie mit 81 Hunden"],"prefix":"10.1055","volume":"50","author":[{"given":"Stephanie","family":"Seibert","sequence":"additional","affiliation":[{"name":"Tierklinik Hofheim, Hofheim am Taunus"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antje","family":"Rohrberg","sequence":"additional","affiliation":[{"name":"Tierklinik Hofheim, Hofheim am Taunus"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Stockinger","sequence":"additional","affiliation":[{"name":"Tierklinik Hofheim, Hofheim am Taunus"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Schaalo","sequence":"additional","affiliation":[{"name":"Tierklinik Hofheim, Hofheim am Taunus"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Imke","family":"M\u00e4rz","sequence":"additional","affiliation":[{"name":"Tierklinik Hofheim, Hofheim am Taunus"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,7,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/j.pt.2011.11.003","article-title":"Canine babesiosis in Europe: How many diseases?","volume":"28","author":"V Matijatko","year":"2012","journal-title":"Trends Parasitol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"119","DOI":"10.2147\/vmrr.s60431","article-title":"Canine babesiosis: a perspective on clinical complications, biomarkers, and treatment","author":"P Kelly","year":"2015","journal-title":"Vet Med Res Rep"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13071-016-1596-0","article-title":"A review of canine babesiosis: The European perspective","volume":"9","author":"L Solano-Gallego","year":"2016","journal-title":"Parasites Vectors"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13071-019-3385-z","article-title":"Establishment of Babesia vulpes n. sp. 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