{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T20:36:52Z","timestamp":1775075812504,"version":"3.50.1"},"reference-count":34,"publisher":"Georg Thieme Verlag KG","issue":"07","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Monbl Augenheilkd"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>(Peri)orbitale Infektionen umfassen ein weites Spektrum vom klinisch h\u00e4ufigen Hordeolum bis zur seltenen, aber bedrohlichen nekrotisierenden Fasziitis. Im ophthalmopathologischen Labor\n\t\t\t\t\tmachen diese Entit\u00e4ten dennoch einen relativ kleinen Anteil der Diagnosen aus, was vor allem daran liegt, dass (peri)orbitale Infektionen i.\u200ad.\u200aR.\u00a0klinisch \u2013 ggf. mit Unterst\u00fctzung der\n\t\t\t\t\tRadiologie und Mikrobiologie \u2013 diagnostiziert werden. In dieser Arbeit wird exemplarisch an einigen Diagnosen die Rolle der ophthalmopathologischen Diagnostik bei (peri)orbitalen Infektionen\n\t\t\t\t\taufgezeigt. Das infekti\u00f6se Hordeolum sollte vom nicht infekti\u00f6sen Chalazion differenziert werden. Hinter einer nodul\u00e4ren Lidverdickung, die als Chalazion eingeordnet und behandelt wird, kann\n\t\t\t\t\tsich eine maligne Neoplasie verbergen. Die Kanalikulitis wird klinisch h\u00e4ufig erst verz\u00f6gert korrekt diagnostiziert und behandelt. Histologisch k\u00f6nnen hier sowohl der Erreger Actinomyces als\n\t\t\t\t\tauch Dakryolithen dargestellt werden. Die nekrotisierende Fasziitis ist eine fulminant verlaufende Infektion der Faszien und kann zu Nekrosen und reduziertem Allgemeinzustand bis hin zu\n\t\t\t\t\tSepsis und Tod f\u00fchren. Im Rahmen der SARS-CoV-2-Pandemie kam es vor allem in Indien geh\u00e4uft zu Mukormykose-F\u00e4llen. Diese Superinfektion wird durch Immunsuppression und Steroideinsatz\n\t\t\t\t\tbeg\u00fcnstigt. Histologisch ist die Mukormykose durch eine Infiltration der Gef\u00e4\u00dfw\u00e4nde durch die Schimmelpilze gekennzeichnet. Die Ophthalmopathologie kann zur Diagnostik und dem Verst\u00e4ndnis\n\t\t\t\t\tder zugrunde liegenden Pathophysiologie dieser Erkrankungen beitragen.<\/jats:p>","DOI":"10.1055\/a-1709-6152","type":"journal-article","created":{"date-parts":[[2022,7,20]],"date-time":"2022-07-20T22:30:28Z","timestamp":1658356228000},"page":"886-893","source":"Crossref","is-referenced-by-count":1,"title":["Schwerpunkt Ophthalmopathologie Orbitainfektion: vom Hordeolum bis zur nekrotisierenden Fasziitis"],"prefix":"10.1055","volume":"239","author":[{"given":"Julia M.","family":"Weller","sequence":"additional","affiliation":[{"name":"Augenheilkunde, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg, Erlangen, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabeth","family":"Messmer","sequence":"additional","affiliation":[{"name":"Augenklinik, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen, Medizinische Fakult\u00e4t, 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