{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T18:27:40Z","timestamp":1787855260813,"version":"build-2784847793"},"reference-count":39,"publisher":"Georg Thieme Verlag KG","issue":"05","license":[{"start":{"date-parts":[[2022,1,26]],"date-time":"2022-01-26T00:00:00Z","timestamp":1643155200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rofo"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Alveolar echinococcosis (AE) is one of the most dangerous human parasitoses. The main site of disease manifestation is the liver (about 98\u200a%). The Echinococcus Multilocularis Ulm Classification for Computed Tomography (EMUC-CT), presented in 2016, was the first compilation of CT morphological criteria of hepatic AE. Studies based on EMUC-CT made it possible to draw conclusions about the development of the lesions in the course of disease beyond purely diagnostic typing. Among the most important findings of these precursor studies was that EMUC-CT type IV presented as an initial lesion, whereas EMUC-CT type III lesions were mostly associated with an advanced disease constellation. An intermodal view of image morphological criteria provides further multi-layered indications for lesion evolution.<\/jats:p>\n                  <jats:p>With the \u201cAlveolar Echinococcosis Ulm Classification\u201d (AEUC), a revision of the previous EMUC-CT was carried out with stage-oriented reorganization of the primary morphologies. Furthermore, an intermodal classification scheme for the evolution of hepatic AE lesions based on AEUC, MRI Kodama classification, and aspects of ultrasound could be outlined.<\/jats:p>\n                  <jats:p>The first stage-oriented CT classification of hepatic AE \u201cAEUC\u201d is based with respect to its lesion characterization on the separate consideration of two classification pillars, the five \u201cprimary morphologies\u201d, AEUC I\u2013V (AEUC II\u2013IV with subcriteria) and the five \u201cpatterns of calcification\u201d. In addition, an intermodal classification scheme presents five stages of lesion evolution: \u201cinitial stage\u201d, \u201cprogressive stage\u201d, \u201cadvanced stage\u201d, \u201ctransitional stage\u201d and \u201cregressive stage\u201d.<\/jats:p>\n                  <jats:p>The imaging modalities differ with respect to their visualization of lesion criteria. This underlines the need for unimodal classification systems. Staging of an AE lesion can be done more accurately by evaluating different modalities.<\/jats:p>","DOI":"10.1055\/a-1710-3669","type":"journal-article","created":{"date-parts":[[2022,1,26]],"date-time":"2022-01-26T18:49:35Z","timestamp":1643222975000},"page":"532-544","source":"Crossref","is-referenced-by-count":17,"title":["Stage-Oriented CT Classification and Intermodal Evolution Model in\u00a0Hepatic Alveolar Echinococcosis"],"prefix":"10.1055","volume":"194","author":[{"given":"Tilmann","family":"Graeter","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, Universit\u00e4tsklinikum Ulm, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian","family":"Schmidberger","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I, Universit\u00e4tsklinikum Ulm, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,1,26]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"343","DOI":"10.3201\/eid0903.020341","article-title":"European echinococcosis registry: human alveolar echinococcosis, Europe, 1982\u20132000","volume":"9","author":"P Kern","year":"2003","journal-title":"Emerg Infect Dis"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.ijid.2008.03.037","article-title":"Echinococcosis: a review","volume":"13","author":"P Moro","year":"2009","journal-title":"Int J Infect Dis"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1007\/s15010-019-01325-2","article-title":"Worldwide literature on epidemiology of human alveolar echinococcosis: a systematic review of research published in the twenty-first century","volume":"47","author":"S Baumann","year":"2019","journal-title":"Infection"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"566","DOI":"10.4269\/ajtmh.1999.61.566","article-title":"An epidemiologic survey of human alveolar echinococcosis in southwestern Germany. 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