{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T12:59:20Z","timestamp":1758632360954,"version":"3.37.3"},"reference-count":37,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rofo"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:p>\n            Background\u2002Transcatheter mitral valve replacement (TMVR) is a treatment option for patients with therapy refractory high-grade mitral valve regurgitation and a high perioperative risk.<\/jats:p><jats:p>During TMVR, the mitral annulus cannot be visualized directly. Therefore, comprehensive pre-interventional planning and a precise visualization of the patient\u2019s specific mitral valve anatomy, outflow tract anatomy and projected anchoring of the device are necessary.<\/jats:p><jats:p>Aim of this review-article is, to assess the role of pre-procedural computed tomography (CT) for TMVR-planning<\/jats:p><jats:p>\n            Methods\u2002Screening and evaluation of relevant guidelines (European Society of Cardiology [ESC], American Heart Association [AHA\/ACC]), meta-analyses and original research using the search terms \u201cTVMR\u201d or \u201cTMVI\u201d and \u201cCT\u201d. In addition to this, the authors included insight from their own clinical experience.<\/jats:p><jats:p>\n            Results\u2002CT allows for accurate measurement of the mitral annulus with high special and adequate temporal resolution in all cardiac phases. Therefore, CT represents a valuable method for accurate prosthesis-sizing.<\/jats:p><jats:p>In addition to that, CT can provide information about the valvular- and outflow-tract-anatomy, mitral valve calcifications, configuration of the papillary muscles and of the left ventricle. Additionally, the interventional access-route may concomitantly be visualized.<\/jats:p><jats:p>\n            Conclusion\u2002CT plays, in addition to echocardiographic imaging, a central role in pre-interventional assessment prior to TMVR. Especially the precise depiction of the left ventricular outflow tract (LVOT) provides relevant additional information, which is very difficult or not possible to be acquired in their entirety with other imaging modalities.<\/jats:p><jats:p>\n            Key Points:\u2002<\/jats:p><jats:p>\n            Citation Format\n          <\/jats:p>","DOI":"10.1055\/a-1718-4182","type":"journal-article","created":{"date-parts":[[2022,3,10]],"date-time":"2022-03-10T23:48:41Z","timestamp":1646956121000},"page":"373-383","source":"Crossref","is-referenced-by-count":6,"title":["CT Planning prior to Transcatheter Mitral Valve Replacement (TMVR)"],"prefix":"10.1055","volume":"194","author":[{"given":"Patrick","family":"Seitz","sequence":"first","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, Heart Center Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4879-0438","authenticated-orcid":false,"given":"Matthias","family":"Gutberlet","sequence":"first","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, Heart Center Leipzig, Leipzig, Germany"},{"name":"Medical Faculty, University of Leipzig, Leipzig, Germany"},{"name":"LHI, Leipzig Heart Institute, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Heiser","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, Heart Center Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8629-8490","authenticated-orcid":false,"given":"Robin F.","family":"Gohmann","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, Heart Center Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thilo","family":"Noack","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Heart Center Leipzig, University of Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katharina","family":"Renatus","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, Heart Center Leipzig, Leipzig, Germany"},{"name":"Medical Faculty, University of Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Lurz","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Heart Center Leipzig, University of Leipzig, Leipzig, Germany"},{"name":"LHI, Leipzig Heart Institute, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Holger","family":"Thiele","sequence":"additional","affiliation":[{"name":"Medical Faculty, University of Leipzig, Leipzig, Germany"},{"name":"Department of Cardiology, Heart Center Leipzig, University of Leipzig, Leipzig, Germany"},{"name":"LHI, Leipzig Heart Institute, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,3,10]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/S0140-6736(06)69208-8","article-title":"Burden of valvular heart diseases: a population-based study","volume":"368","author":"V T Nkomo","year":"2006","journal-title":"Lancet"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"2374","DOI":"10.1056\/NEJMe1812279","article-title":"Percutaneous Repair of Secondary Mitral Regurgitation \u2013 A Tale of Two Trials","volume":"379","author":"R A Nishimura","year":"2018","journal-title":"N Engl J Med"},{"key":"ref3","first-page":"689","article-title":"Mitral valve disease \u2013 morphology and mechanisms","volume":"12","author":"R A 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A clinicopathological study of fourteen cases","volume":"267","author":"D Korn","year":"1962","journal-title":"N Engl J Med"},{"key":"ref35","first-page":"1194","article-title":"Concomitant mitral annular calcification and severe aortic stenosis: prevalence, characteristics and outcome following transcatheter aortic valve replacement","volume":"38","author":"Y Abramowitz","year":"2017","journal-title":"Eur Heart J"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1016\/j.jcmg.2020.03.013","article-title":"A Cardiac Computed Tomography-Based Score to Categorize Mitral Annular Calcification Severity and Predict Valve Embolization","volume":"13","author":"M Guerrero","year":"2020","journal-title":"JACC Cardiovasc Imaging"},{"issue":"S 07","key":"ref37","doi-asserted-by":"crossref","first-page":"S640","DOI":"10.21037\/jtd.2017.06.99","article-title":"Multimodality imaging assessment of mitral valve anatomy in planning for mitral valve repair in secondary mitral regurgitation","volume":"9","author":"R Capoulade","year":"2017","journal-title":"J Thorac Dis"}],"container-title":["R\u00f6Fo - Fortschritte auf dem Gebiet der R\u00f6ntgenstrahlen und der bildgebenden Verfahren"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1718-4182.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,21]],"date-time":"2022-04-21T00:37:50Z","timestamp":1650501470000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1718-4182"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,10]]},"references-count":37,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2022,3,28]]},"published-print":{"date-parts":[[2022,4]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1718-4182","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1438-9029","1438-9010"],"issn-type":[{"type":"print","value":"1438-9029"},{"type":"electronic","value":"1438-9010"}],"subject":[],"published":{"date-parts":[[2022,3,10]]}}}