{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T14:33:09Z","timestamp":1783780389922,"version":"3.55.0"},"reference-count":39,"publisher":"Georg Thieme Verlag KG","issue":"03\/04","license":[{"start":{"date-parts":[[2022,2,18]],"date-time":"2022-02-18T00:00:00Z","timestamp":1645142400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"SaluVet GmbH"},{"name":"Laboklin GmbH & Co.KG"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Planta Med"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Administration of essential oils as natural plant products with antimicrobial activity might be an alternative to antibiotic treatment of bovine respiratory disease. The aim of this study\n\t\t\t\t\twas to analyse the in vitro antimicrobial activity of 11 essential oils against Pasteurella multocida isolated from the respiratory tract of calves using microdilution with\n\t\t\t\t\tdetermination of minimum inhibitory and bactericidal concentration as well as agar disc diffusion. Additionally, antimicrobial activity against Mannheimia haemolytica and bacteria in\n\t\t\t\t\tthe Mannheimia clade was assessed by agar disc diffusion. Seven essential oil mixtures were also tested against all bacterial isolates. P. multocida was strongly inhibited by\n\t\t\t\t\tcinnamon cassia and lemongrass oil followed by coriander, winter savory, thyme, clove, and peppermint oil in the microdilution assays. Eucalyptus, wintergreen, spruce, and star anise oil\n\t\t\t\t\tshowed lower activity. Comparison of both methods revealed an underestimation of cinnamon cassia oil activity by agar disc diffusion and conflicting results for wintergreen oil in\n\t\t\t\t\tmicrodilution, which precipitated in broth. Cinnamon cassia, thyme, wintergreen, lemongrass, and winter savory oil all showed strong antimicrobial activity against M.\u00a0haemolytica.\n\t\t\t\t\tBacteria in the Mannheimia clade were mostly inhibited by cinnamon cassia and thyme oil. Pasteurella isolates were more susceptible to inhibition by essential oils than\n\t\t\t\t\t\tMannheimia isolates. Essential oil mixtures did not show stronger antibacterial activity than single essential oils. In conclusion, cinnamon cassia and lemongrass as well as\n\t\t\t\t\tcoriander, winter savory, and thyme oil are promising candidates for treatment of P. multocida-associated bovine respiratory infections.<\/jats:p>","DOI":"10.1055\/a-1726-9291","type":"journal-article","created":{"date-parts":[[2022,2,19]],"date-time":"2022-02-19T00:23:45Z","timestamp":1645230225000},"page":"274-281","source":"Crossref","is-referenced-by-count":9,"title":["Screening of Antimicrobial Activity of Essential Oils against Bovine Respiratory Pathogens \u2013 Focusing on Pasteurella multocida"],"prefix":"10.1055","volume":"88","author":[{"given":"Doris","family":"Bismarck","sequence":"additional","affiliation":[{"name":"Laboklin GmbH & Co.KG, Bad Kissingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens","family":"Becker","sequence":"additional","affiliation":[{"name":"Clinic for Ruminants, Vetsuisse-Faculty, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Laboklin GmbH & Co.KG, Bad Kissingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vera","family":"Becher","sequence":"additional","affiliation":[{"name":"SaluVet GmbH, Bad Waldsee, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Nau","sequence":"additional","affiliation":[{"name":"SaluVet GmbH, Bad Waldsee, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Mayer","sequence":"additional","affiliation":[{"name":"SaluVet GmbH, Bad Waldsee, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,2,18]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1017\/S1466252307001375","article-title":"Mannheimia haemolytica and bovine 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CLSI supplement VET08","author":"CLSI","year":"2018"},{"key":"ref36","doi-asserted-by":"crossref","DOI":"10.1007\/978-0-387-98141-3","volume-title":"ggplot2: Elegant graphics for data analysis","author":"H Wickham","year":"2009"},{"key":"ref37","first-page":"754","volume-title":"An Aligned Rank Transform Procedure for Multifactor Contrast Tests","author":"L A Elkin","year":"2021"},{"key":"ref38","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-8274-2202-6","volume-title":"Lexikon der Arzneipflanzen und Drogen","author":"K Hiller","year":"2010","edition":"2nd ed."},{"key":"ref39","volume-title":"WHO monographs on selected medicinal plants, Volume 2","author":"World Health Organization","year":"2002"},{"key":"ref40","volume-title":"ESCOP Monographs Online Series, Caryophylli Aetheroleum \u2013 clove oil","author":"European Scientific Cooperative on Phytotherapy","year":"2014"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1080\/10412905.1994.9698332","article-title":"The chemical composition of the essential oil of Cymbopogon flexuosus (Steud) Wats. Growing in Northeast India","volume":"6","author":"S C Nath","year":"1994","journal-title":"J Essent Oil Res"}],"container-title":["Planta Medica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1726-9291.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T22:38:30Z","timestamp":1648679910000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1726-9291"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,18]]},"references-count":39,"journal-issue":{"issue":"03\/04","published-online":{"date-parts":[[2022,3,30]]},"published-print":{"date-parts":[[2022,3]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1726-9291","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0032-0943","1439-0221"],"issn-type":[{"value":"0032-0943","type":"print"},{"value":"1439-0221","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,18]]}}}