{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T09:25:56Z","timestamp":1748251556879},"reference-count":43,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg G Grosstiere Nutztiere"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>In einem Schweinemastbetrieb in S\u00fcddeutschland konnten \u00fcber einen Zeitraum von 4\u2005Wochen Hinterhandl\u00e4hmungen bei 2\u2005Altersgruppen (50\u2005kg sowie 60\u2005kg) beobachtet werden. Die Morbidit\u00e4t bei den beiden Altersgruppen war mit 3,3\u2005% niedrig, der Gro\u00dfteil der betroffenen Tiere musste jedoch aufgrund einer fortschreitenden Paralyse der Hintergliedma\u00dfen euthanasiert werden. Im Rahmen der pathomorphologischen Untersuchung von 2\u2005Mastschweinen konnte eine hochgradige und diffuse lymphohistiozyt\u00e4re Meningoenzephalomyelitis und Vaskulitis festgestellt werden. Immunhistochemisch wurde in allen Arealen des zentralen Nervensystems und in mehreren Zelltypen (Neuronen, Gliazellen, Endothelzellen, mononukle\u00e4re Zellen) Porzines Teschovirus-Antigen nachgewiesen. Die Untersuchung von R\u00fcckenmarksproben mittels PCR ergab den Nachweis von Porzinen Teschoviren. Der anschlie\u00dfend durchgef\u00fchrten phylogenetischen Analyse zufolge wiesen die PCR positiven Proben die h\u00f6chste Identit\u00e4t (88\u2005% Vollgenomsequenz) zum Porzinen Teschovirus A11 Stamm \u201eDresden\u201c auf. Andere differentialdiagnostisch in Frage kommende Pathogene konnten mittels PCR, bakteriologischer Untersuchung und Sequenzierung nicht nachgewiesen werden. In dem Mastbestand traten nach ca. 4\u2005Wochen keine weiteren F\u00e4lle von L\u00e4hmungserscheinungen mehr auf.<\/jats:p>","DOI":"10.1055\/a-1729-3677","type":"journal-article","created":{"date-parts":[[2022,3,2]],"date-time":"2022-03-02T23:42:28Z","timestamp":1646264548000},"page":"59-67","source":"Crossref","is-referenced-by-count":1,"title":["Hinterhandl\u00e4hmungen bei Mastschweinen im Zusammenhang mit einem neuen Stamm des porzinen Teschovirus A11"],"prefix":"10.1055","volume":"50","author":[{"given":"Julia","family":"Stadler","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Schweine am Zentrum f\u00fcr Klinische Tiermedizin, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sigena","family":"Junker","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Schweine am Zentrum f\u00fcr Klinische Tiermedizin, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Gr\u00fcndl","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Schweine am Zentrum f\u00fcr Klinische Tiermedizin, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastian","family":"Fr\u00f6hlich","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Schweine am Zentrum f\u00fcr Klinische Tiermedizin, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Beisl","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Schweine am Zentrum f\u00fcr Klinische Tiermedizin, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanne","family":"Z\u00f6ls","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Schweine am Zentrum f\u00fcr Klinische 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M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Sehl","sequence":"additional","affiliation":[{"name":"Friedrich-Loeffler-Institut, Bundesforschungsinstitut f\u00fcr Tiergesundheit"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dirk","family":"H\u00f6per","sequence":"additional","affiliation":[{"name":"Friedrich-Loeffler-Institut, Bundesforschungsinstitut f\u00fcr Tiergesundheit"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Unterweger","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik f\u00fcr Schweine, Department f\u00fcr Nutztiere und \u00f6ffentliches Gesundheitswesen in der Veterin\u00e4rmedizin, Veterin\u00e4rmedizinische Universit\u00e4t Wien"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Ladinig","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik f\u00fcr Schweine, Department f\u00fcr Nutztiere und \u00f6ffentliches Gesundheitswesen in der Veterin\u00e4rmedizin, Veterin\u00e4rmedizinische Universit\u00e4t Wien"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Mayer","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Tierpathologie am Zentrum f\u00fcr klinische Tiermedizin, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,3,2]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/j.1439-0450.1994.tb00228.x","article-title":"Grouping of porcine enteroviruses by indirect immunofluorescence and description of two new serotypes","volume":"41","author":"J Auerbach","year":"1994","journal-title":"Journal of Veterinary Medicine, Series B"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1128\/JVI.75.4.1620-1631.2001","article-title":"Porcine teschoviruses comprise 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