{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T14:37:03Z","timestamp":1789396623061,"version":"build-2803163510"},"reference-count":45,"publisher":"Georg Thieme Verlag KG","issue":"07","license":[{"start":{"date-parts":[[2022,3,16]],"date-time":"2022-03-16T00:00:00Z","timestamp":1647388800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Geburtshilfe Frauenheilkd"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>There are currently no up-to-date evidence-based recommendations on the preferred method to induce labour after previous Caesarean section, especially for patients with unripe cervix, as\n          randomised controlled studies are lacking. Intravenous oxytocin and misoprostol are contraindicated in these women because of the high risk of uterine rupture. In women with ripe cervix\n          (Bishop Score &gt;\u00a06), intravenous administration of oxytocin is an effective procedure with comparable rates of uterine rupture to those with spontaneous onset of labour. Vaginal\n          prostaglandin E2 (PGE2) and mechanical methods (balloon catheters, hygroscopic cervical dilators) are effective methods to induce labour in pregnant women with unripe\n          cervix and previous Caesarean section. According to current guidelines, the administration of PGE2 is associated with a higher rate of uterine rupture compared to balloon\n          catheters. Balloon catheters are therefore a suitable alternative to PGE2 to induce labour after previous Caesarean section, even though this is an off-label use. In addition to\n          two meta-analyses published in 2016, 12 mostly retrospective cohort\/observational studies with low to moderate levels of evidence have been published on mechanical methods of cervical\n          ripening after previous Caesarean section. But because of the significant heterogeneity of the studies, substantial differences in study design, and insufficient numbers of pregnant women\n          included in the studies, it is not possible to make any evidence-based recommendations based on these studies. According to a recent meta-analysis, the average rate using balloon catheters\n          is approximately 53% and the average rate after spontaneous onset of labour is 72%. The uterine rupture rate was 0.2\u20130.9% for vaginal PGE2 and 0.56\u20130.94% for balloon catheters and\n          is therefore comparable to the uterine rupture rate associated with spontaneous onset of labour. According to the product informations, hygroscopic cervical dilators (Dilapan-S) are\n          currently the only method which is not contraindicated for cervical ripening\/induction of labour in women with previous Caesarean section, although data are insufficient. Well-designed,\n          randomised, controlled studies with sufficient case numbers comparing balloon catheters and hygroscopic cervical dilators with mechanical methods and vaginal prostaglandin E2\/oral\n          misoprostol are therefore necessary to allow proper decision-making.<\/jats:p>","DOI":"10.1055\/a-1731-7441","type":"journal-article","created":{"date-parts":[[2022,3,17]],"date-time":"2022-03-17T00:14:22Z","timestamp":1647476062000},"page":"727-735","source":"Crossref","is-referenced-by-count":6,"title":["Mechanical Methods for the Induction of Labour After Previous Caesarean Section \u2013 An Updated, Evidence-based Review"],"prefix":"10.1055","volume":"82","author":[{"given":"Werner","family":"Rath","sequence":"additional","affiliation":[{"name":"Medizinische Fakult\u00e4t, Gyn\u00e4kologie und Geburtshilfe, Universit\u00e4tsklinikum Schleswig-Holstein, Campus Kiel, Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Hellmeyer","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Gyn\u00e4kologie und Geburtsmedizin, Vivantes Klinikum im Friedrichshain, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panagiotis","family":"Tsikouras","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Democritus University of Thrace, Alexandroupolis, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Stelzl","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik f\u00fcr Gyn\u00e4kologie, Geburtshilfe und Gyn\u00e4kologische Endokrinologie, Kepler Universit\u00e4tsklinikum, Johannes Kepler Universit\u00e4t Linz, Linz, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,3,16]]},"reference":[{"key":"ref2","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1111\/j.1471-0528.2004.00287.x","article-title":"Risk of induction of labour in women with a uterine scar from previous low transcervical caesarean section","volume":"111","author":"A Locatelli","year":"2004","journal-title":"BJOG"},{"issue":"06","key":"ref3","doi-asserted-by":"publisher","first-page":"CD009792","DOI":"10.1002\/14651858.CD009792.pub3","article-title":"Methods of term labour induction for women with a previous caesarean section (Review)","author":"HM West","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1097\/01.AOG.0000254169.49346.e9","article-title":"Outcomes of induction of labor after one prior cesarean","volume":"109","author":"WA Grobman","year":"2007","journal-title":"Obstet Gynecol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1097\/OGX.0b013e318273feeb","article-title":"Uterine rupture during trial of labor: Controversy of induction\u2019s methods","volume":"67","author":"E Ophir","year":"2012","journal-title":"Obstet Gynecol Surv"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.jogoh.2017.12.002","article-title":"French validation and adaption of the Grobman normgram for prediction of vaginal birth after cesarean delivery","volume":"47","author":"JB Haumonte","year":"2018","journal-title":"J Gynecol Obstet Hum Reprod"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"51.e1","DOI":"10.1016\/j.ajog.2011.09.022","article-title":"Association of induction of labor and uterine rupture in women attempting vaginal birth after cesarean: a survival analysis","volume":"206","author":"LM Harper","year":"2012","journal-title":"AJOG"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1016\/j.jogoh.2018.09.006","article-title":"Obstetric outcomes associated with induction of labour after caesarean section","volume":"47","author":"S Gobillot","year":"2018","journal-title":"J Gynecol Obstet Hum Reprod"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1140","DOI":"10.1055\/s-0035-1558171","article-title":"Misoprostol for induction of labour after previous caesarean section \u2013 forever a \u201cNo go\u201d?","volume":"75","author":"W Rath","year":"2015","journal-title":"Geburtshilfe Frauenheilkd"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"870","DOI":"10.1055\/a-1519-7713","article-title":"Induction of Labour. 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