{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,28]],"date-time":"2022-03-28T23:17:43Z","timestamp":1648509463344},"reference-count":5,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dtsch Med Wochenschr"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Hintergrund, Anamnese und Untersuchungen\u2002Das Amelanotische Melanom (AM) ist ein Subtyp des Melanoms, bei dem die Melanozyten wenig oder keine Melaninsynthese betreiben. Da es klinisch nicht die typische, dunkle Pigmentierung des Melanoms zeigt, wird es oftmals als gutartiger Hauttumor oder entz\u00fcndliche Dermatose verkannt und daher zu sp\u00e4t oder fehlerhaft behandelt. Diese \u00dcbersicht aus 4 F\u00e4llen dient der Veranschaulichung der Warnzeichen von plantaren AM (PAM), die jedem klinisch t\u00e4tigen Mediziner bekannt sein sollten.<\/jats:p><jats:p>\n          Therapie und Verlauf\u2002Wir pr\u00e4sentieren eine Fallserie aus 4\u00a0Patienten mit PAM und beschreiben detailliert die Bandbreite des klinischen Erscheinungsbildes sowie den Krankheitsverlauf.<\/jats:p><jats:p>\n          Folgerung\u2002PAM k\u00f6nnen verschiedene klinische Auspr\u00e4gungen annehmen und insbesondere \u00e4ltere Patienten mit multiplen Nebenerkrankungen sind gef\u00e4hrdet f\u00fcr eine Fehldiagnose. Wir empfehlen daher generell eine diagnostische Biopsie bei jeder plantaren Ulzeration, wenn diese nach 6 Wochen kein Therapieansprechen zeigt.<\/jats:p>","DOI":"10.1055\/a-1748-6050","type":"journal-article","created":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T23:42:17Z","timestamp":1647387737000},"page":"351-354","source":"Crossref","is-referenced-by-count":0,"title":["Das plantare amelanotische Melanom: Ein Wolf im Schafspelz"],"prefix":"10.1055","volume":"147","author":[{"given":"Ines","family":"Bertlich","sequence":"additional","affiliation":[{"name":"Dermatologie, Universit\u00e4tsklinikum Heidelberg, INF 440, 69120 Heidelberg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Enk","sequence":"additional","affiliation":[{"name":"Dermatologie, Universit\u00e4tsklinikum Heidelberg, INF 440, 69120 Heidelberg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferdinand","family":"Toberer","sequence":"additional","affiliation":[{"name":"Dermatologie, Universit\u00e4tsklinikum Heidelberg, INF 440, 69120 Heidelberg"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,3,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1097\/00000658-200206000-00017","article-title":"Long-term survival in 2505 patients with melanoma with regional lymph node metastasis","volume":"235","author":"R R White","year":"2002","journal-title":"Ann Surg"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"3618","DOI":"10.1245\/s10434-013-3089-0","article-title":"Prognosis of acral melanoma: a series of 281 patients","volume":"20","author":"D M Bello","year":"2013","journal-title":"Ann Surg Oncol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1097\/CMR.0000000000000337","article-title":"Clinical and dermoscopic features of truly amelanotic plantar melanoma","volume":"27","author":"V De Giorgi","year":"2017","journal-title":"Melanoma Res"},{"key":"ref5","first-page":"183","article-title":"Factors of delay in the diagnosis of melanoma","volume":"13","author":"R Betti","year":"2003","journal-title":"Eur J Dermatol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1097\/CMR.0000000000000294","article-title":"Melanoma masquerading as nonmelanocytic lesions","volume":"26","author":"A Detrixhe","year":"2016","journal-title":"Melanoma research"}],"container-title":["DMW - Deutsche Medizinische Wochenschrift"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1748-6050.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T23:44:01Z","timestamp":1647387841000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1748-6050"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":5,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2022,3,15]]},"published-print":{"date-parts":[[2022,3]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1748-6050","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0012-0472","1439-4413"],"issn-type":[{"value":"0012-0472","type":"print"},{"value":"1439-4413","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3]]}}}