{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T17:14:40Z","timestamp":1788887680859,"version":"build-2803163510"},"reference-count":37,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Monbl Augenheilkd"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Das Glaukom bezeichnet eine Gruppe chronischer Augenkrankheiten, die zu einer Degeneration der retinalen Ganglienzellen (RGZ) und ihrer Axone f\u00fchren, gefolgt von einem irreversiblen Verlust\n\t\t\t\t\tdes Sehverm\u00f6gens des Patienten. Das Glaukom ist eine Krankheit, die sich zun\u00e4chst asymptomatisch entwickelt, wobei die ersten Symptome erst in einem fortgeschrittenen Stadium dieser\n\t\t\t\t\tAugenkrankheit auftreten. Aus diesem Grund ist es stets notwendig, modernste Technologien und Methoden zur Identifizierung und Charakterisierung neuer, spezifischer Biomarker f\u00fcr die\n\t\t\t\t\tFr\u00fchdiagnose des Glaukoms zu entwickeln. Daher stellt die Analyse biologischer Fl\u00fcssigkeiten, wie in diesem Fall der Tr\u00e4nenfl\u00fcssigkeit von Patienten, eine attraktive Quelle f\u00fcr die\n\t\t\t\t\tIdentifizierung neuer spezifischer sowie sensitiver Biomarker bei Glaukom dar. Diese Biomarker k\u00f6nnten an den pathophysiologischen Prozessen des Glaukoms beteiligt sein oder m\u00f6glicherweise\n\t\t\t\t\tzur diagnostischen Differenzierung verschiedener Glaukomtypen dienen.<\/jats:p>","DOI":"10.1055\/a-1749-6972","type":"journal-article","created":{"date-parts":[[2022,2,25]],"date-time":"2022-02-25T01:23:22Z","timestamp":1645752202000},"page":"165-168","source":"Crossref","is-referenced-by-count":2,"title":["Tr\u00e4nenfilmspezifische Biomarker bei Glaukompatienten"],"prefix":"10.1055","volume":"239","author":[{"given":"Kristian Nzogang","family":"Fomo","sequence":"additional","affiliation":[{"name":"Experimentelle und Translationale Ophthalmologie, Universit\u00e4tsmedizin der Johannes Gutenberg-Universit\u00e4t Mainz, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carsten","family":"Schmelter","sequence":"additional","affiliation":[{"name":"Experimentelle und Translationale Ophthalmologie, Universit\u00e4tsmedizin der Johannes 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