{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T05:51:46Z","timestamp":1789105906095,"version":"build-2803163510"},"reference-count":46,"publisher":"Georg Thieme Verlag KG","issue":"08","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rofo"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:p>\n            Purpose\u2002Coronary artery calcification is a frequent incidental finding on thoracic computed tomography (CT) performed for non-cardiac indications. On electrocardiogram-gated cardiac CT, it is an established marker of coronary artery disease and is associated with increased risk of subsequent cardiac events.<\/jats:p><jats:p>\n            Materials and Methods\u2002This review discusses the current evidence and guidelines regarding the reporting of coronary artery calcification on non-electrocardiogram-gated thoracic CT performed for non-cardiac indications.<\/jats:p><jats:p>\n            Results\u2002For patients undergoing routine thoracic CT, coronary artery calcification is associated with an increased risk of myocardial infarction and mortality. Coronary artery calcification can be accurately assessed on non-gated thoracic CT compared to gated CT. Guidelines support the reporting of coronary artery calcification on thoracic CT. However, radiologist opinions vary. The identification of coronary artery calcification on thoracic CT may identify patients with previously unknown coronary artery disease. For asymptomatic patients this may trigger an assessment of modifiable cardiovascular risk factors and guide the appropriate use of preventative medications.<\/jats:p><jats:p>\n            Conclusion\u2002Future research will address whether changing management based on calcification on thoracic CT will improve outcomes and automated assessment of calcification using machine learning techniques.<\/jats:p><jats:p>\n            Key Points:\n          <\/jats:p><jats:p>\n            Citation Format\n          <\/jats:p>","DOI":"10.1055\/a-1752-0577","type":"journal-article","created":{"date-parts":[[2022,3,10]],"date-time":"2022-03-10T23:48:41Z","timestamp":1646956121000},"page":"833-840","source":"Crossref","is-referenced-by-count":3,"title":["What should we do about Coronary Calcification on Thoracic CT?"],"prefix":"10.1055","volume":"194","author":[{"given":"Oliver","family":"Llewellyn","sequence":"additional","affiliation":[{"name":"Department of Radiology, Royal Infirmary of Edinburgh, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3556-2428","authenticated-orcid":false,"given":"Michelle C.","family":"Williams","sequence":"additional","affiliation":[{"name":"Centre for Cardiovascular Science, The University of Edinburgh Centre for Cardiovascular Science, Edinburgh, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,3,10]]},"reference":[{"key":"ref2","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1083\/jcb.201412052","article-title":"Recent insights into the cellular biology of atherosclerosis","volume":"209","author":"I Tabas","year":"2015","journal-title":"J Cell Biol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/S0140-6736(13)61754-7","article-title":"18F-fluoride positron emission tomography for identification of ruptured and high-risk coronary atherosclerotic plaques: a prospective clinical trial","volume":"383","author":"N V Joshi","year":"2014","journal-title":"Lancet"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1038\/nrcardio.2014.60","article-title":"Comprehensive plaque assessment by coronary CT angiography","volume":"11","author":"P Maurovich-Horvat","year":"2014","journal-title":"Nat Rev Cardiol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1161\/CIRCULATIONAHA.119.044720","article-title":"Low-Attenuation Noncalcified Plaque on Coronary Computed Tomography Angiography Predicts Myocardial Infarction: Results From the Multicenter SCOT-HEART Trial (Scottish Computed Tomography of the HEART)","volume":"141","author":"M C Williams","year":"2020","journal-title":"Circulation"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1056\/NEJMoa072100","article-title":"Coronary calcium as a predictor of coronary events in four racial or ethnic groups","volume":"358","author":"R Detrano","year":"2008","journal-title":"N Engl J Med"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1053\/euhj.2002.3240","article-title":"Coronary calcification detected by electron-beam computed tomography and myocardial infarction. 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