{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T10:37:02Z","timestamp":1780915022924,"version":"3.54.1"},"reference-count":24,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2022,2,4]],"date-time":"2022-02-04T00:00:00Z","timestamp":1643932800000},"content-version":"vor","delay-in-days":34,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AJP Rep"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Streptococcus gallolyticus is an uncommon cause of neonatal infections. We describe the first case of fulminant lethal neonatal sepsis due to S. gallolyticus reported in literature. Our patient was an extremely low birth weight premature infant born to a mother with prolonged rupture of amniotic membranes and chorioamnionitis. We also review the cases of neonatal S. gallolyticus infections reported in literature. Fifty-eight percent neonatal S. gallolyticus infections presented in the first week of life. Importantly, S. gallolyticus meningitis is more commonly reported with early-onset infections compared with group B streptococcal meningitis, which is more common with late-onset infections. Streptococcus gallolyticus should be included in differential for neonatal sepsis, particularly in the presence of meningitis in the first week of life. Most cases are sensitive to penicillin; however, cases of reduced sensitivity to penicillin have also been reported.<\/jats:p>","DOI":"10.1055\/a-1762-0096","type":"journal-article","created":{"date-parts":[[2022,2,5]],"date-time":"2022-02-05T01:01:35Z","timestamp":1644022895000},"page":"e117-e122","source":"Crossref","is-referenced-by-count":10,"title":["Early-Onset Fulminant Sepsis in a Preterm Neonate due to Streptococcus gallolyticus: A Case Report and Literature Review"],"prefix":"10.1055","volume":"12","author":[{"given":"Chandler","family":"Williams","sequence":"additional","affiliation":[{"name":"Division of Neonatal-Perinatal Medicine, Department of Pediatrics, The University of Tennessee Health Science Center, Memphis, Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3741-2506","authenticated-orcid":false,"given":"Rishika P.","family":"Sakaria","sequence":"additional","affiliation":[{"name":"Division of Neonatal-Perinatal Medicine, Department of Pediatrics, The University of Tennessee Health Science Center, Memphis, Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massroor","family":"Pourcyrous","sequence":"additional","affiliation":[{"name":"Division of Neonatal-Perinatal Medicine, Department of Pediatrics, The University of Tennessee Health Science Center, Memphis, Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,3,14]]},"reference":[{"issue":"07","key":"ref1","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1128\/JCM.02977-15","article-title":"An update on the Streptococcus bovis group: classification, identification, and disease associations","volume":"54","author":"J P Dekker","year":"2016","journal-title":"J Clin Microbiol"},{"issue":"03","key":"ref2","doi-asserted-by":"crossref","first-page":"000200","DOI":"10.1099\/acmi.0.000200","article-title":"Streptococcus gallolyticus subspecies pasteurianus causing early onset neonatal sepsis complicated by solitary liver abscess in a preterm infant","volume":"3","author":"O Geetha","year":"2021","journal-title":"Access Microbiol"},{"issue":"03","key":"ref3","doi-asserted-by":"crossref","first-page":"480","DOI":"10.3390\/ijms20030480","article-title":"An overview on Streptococcus bovis\/Streptococcus equinus complex isolates: identification to the species\/subspecies level and antibiotic resistance","volume":"20","author":"A Pompilio","year":"2019","journal-title":"Int J Mol Sci"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1099\/ijs.0.02361-0","article-title":"Reappraisal of the taxonomy of the Streptococcus bovis\/Streptococcus equinus complex and related species: description of Streptococcus gallolyticus subsp. gallolyticus subsp. nov., S. gallolyticus subsp. macedonicus subsp. nov. and S. gallolyticus subsp. pasteurianus subsp. nov","volume":"53","author":"L Schlegel","year":"2003","journal-title":"Int J Syst Evol Microbiol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.meegid.2014.09.017","article-title":"Genomics, evolution, and molecular epidemiology of the Streptococcus bovis\/Streptococcus equinus complex (SBSEC)","volume":"33","author":"C Jans","year":"2015","journal-title":"Infect Genet Evol"},{"issue":"09","key":"ref6","first-page":"000264","article-title":"Streptococcus lutetiensis neonatal meningitis with empyema","volume":"3","author":"A T Yu","year":"2021","journal-title":"Access Microbiol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1099\/jmm.0.006551-0","article-title":"Neonatal bacterial meningitis caused by Streptococcus gallolyticus subsp. pasteurianus","volume":"58","author":"S Onoyama","year":"2009","journal-title":"J Med Microbiol"},{"key":"ref8","first-page":"474","article-title":"Relative penicillin resistance in Streptococcus bovis. 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