{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T20:26:48Z","timestamp":1750105608384,"version":"3.37.0"},"reference-count":34,"publisher":"American Academy of Audiology","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["j am acad audiol"],"published-print":{"date-parts":[[2022,4,1]]},"abstract":"<jats:p><jats:bold>Abstract<\/jats:bold>  <jats:bold>Background<\/jats:bold>\u2003Frequency tuning of ocular vestibular evoked myogenic potential (oVEMP) refers to the frequency of tone burst that produces the largest amplitude oVEMP. There is an ever-growing pool of published studies that found the frequency tuning of\n oVEMP distinctly different in M\u00e9ni\u00e8re's disease than the age-matched controls and benign paroxysmal positional vertigo. However, recording oVEMP in response to many frequencies makes an already lengthy vestibular test battery even more cumbersome and time-consuming. <jats:bold>Purpose<\/jats:bold>\u2003The\n aim of this study was to develop a novel time-saving stimulus that produces reliable results. <jats:bold>Research Design<\/jats:bold>\u2003Prospective study. <jats:bold>Study Sample<\/jats:bold>\u2003The study included 25 young, healthy adults. <jats:bold>Data Collection<\/jats:bold>\u2003The tone-bursts of 2000, 1500, 1000, 750,\n 500, and 250\u2009Hz were generated and sequenced in this order to prepare a stimulus for simultaneous multifrequency (SiMFy) oVEMP. The response parameters of SiMFy and conventional oVEMP methods were compared. <jats:bold>Results<\/jats:bold>\u2003No significant difference in peak-to-peak amplitude\n and frequency tuning existed between conventional and SiMFy oVEMP (p\u2009&gt;\u20090.05). SiMFy had better test\u2010retest reliability and was less time-consuming than the conventional oVEMP. <jats:bold>Conclusions<\/jats:bold>\u2003SiMFy is a time-saving and reliable stimulus for obtaining frequency\n tuning of oVEMP with no compromise on the outcomes. It can be immediately applied in most commercially available evoked potential systems with a facility for loading an external stimulus.<\/jats:p>","DOI":"10.1055\/a-1772-4866","type":"journal-article","created":{"date-parts":[[2022,2,16]],"date-time":"2022-02-16T01:37:40Z","timestamp":1644975460000},"page":"224-231","source":"Crossref","is-referenced-by-count":2,"title":["Simultaneous Multifrequency (SiMFy) Stimulus: A Novel and Reliable Stimulus for Frequency Tuning of Ocular Vestibular-Evoked Myogenic Potentials"],"prefix":"10.3766","volume":"33","author":[{"given":"Niraj Kumar","family":"Singh","sequence":"first","affiliation":[{"name":"Department of Audiology, All India Institute of Speech and Hearing, Manasagangothri, Mysore, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mamatha Hunsur","family":"Ravikumar","sequence":"additional","affiliation":[{"name":"Department of Audiology, All India Institute of Speech and Hearing, Manasagangothri, Mysore, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandeep","family":"Maruthy","sequence":"additional","affiliation":[{"name":"Department of Audiology, All India Institute of Speech and Hearing, Manasagangothri, Mysore, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2087","reference":[{"issue":"03","key":"ref1","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1097\/MAO.0b013e3182488046","article-title":"Altered frequency dynamics of cervical and ocular vestibular evoked myogenic potentials in patients with M\u00e9ni\u00e8re's disease","volume":"33","author":"J S Sandhu","year":"2012","journal-title":"Otol Neurotol"},{"issue":"04","key":"ref2","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1159\/000336959","article-title":"Tuning characteristics of ocular and cervical vestibular evoked myogenic potentials in intact and dehiscent ears","volume":"17","author":"R L Taylor","year":"2012","journal-title":"Audiol Neurotol"},{"issue":"01","key":"ref3","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1159\/000324858","article-title":"Ocular vestibular evoked myogenic potentials: frequency tuning to air-conducted acoustic stimuli in healthy subjects and M\u00e9ni\u00e8re's disease","volume":"17","author":"S M Winters","year":"2012","journal-title":"Audiol Neurotol"},{"issue":"06","key":"ref4","doi-asserted-by":"crossref","first-page":"e65","DOI":"10.1097\/AUD.0b013e31828fc9f2","article-title":"Effects of age on the tuning of the cVEMP and oVEMP","volume":"34","author":"E G Piker","year":"2013","journal-title":"Ear Hear"},{"issue":"09","key":"ref5","first-page":"764","article-title":"Utility of the frequency tuning measure of oVEMP in differentiating M\u00e9ni\u00e8re's disease from BPPV","volume":"27","author":"N K Singh","journal-title":"J Am Acad Audiol"},{"issue":"02","key":"ref6","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1097\/AUD.0000000000000482","article-title":"Characterizing the age and stimulus frequency interaction for ocular vestibular-evoked myogenic potentials","volume":"39","author":"N K Singh","year":"2018","journal-title":"Ear Hear"},{"issue":"12","key":"ref7","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1080\/14992027.2021.1893840","article-title":"Effect of advancing age on inter-frequency amplitude ratio of ocular vestibular evoked myogenic potentials","volume":"60","author":"N K Singh","year":"2021","journal-title":"Int J Audiol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.heares.2014.02.001","article-title":"Ocular vestibular evoked myogenic potential frequency tuning in certain M\u00e9ni\u00e8re's disease","volume":"310","author":"C Jerin","year":"2014","journal-title":"Hear Res"},{"issue":"03","key":"ref9","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1097\/AUD.0000000000000263","article-title":"Frequency\u2013amplitude ratio of ocular vestibular-evoked myogenic potentials for detecting M\u00e9ni\u00e8re's disease: a preliminary investigation","volume":"37","author":"N K Singh","journal-title":"Ear Hear"},{"issue":"01","key":"ref10","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1080\/14992027.2018.1529440","article-title":"Inter-frequency amplitude ratio of oVEMP for differentiating M\u00e9ni\u00e8re's disease from BPPV: clinical validation using a double-blind approach","volume":"58","author":"N K Singh","year":"2019","journal-title":"Int J Audiol"},{"issue":"08","key":"ref11","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1097\/MAO.0b013e31822e5ac9","article-title":"Ocular vestibular evoked myogenic potentials in response to air-conducted sound in M\u00e9ni\u00e8re's disease","volume":"32","author":"S M Winters","year":"2011","journal-title":"Otol Neurotol"},{"issue":"03","key":"ref12","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1177\/0333102411434166","article-title":"Vestibular evoked myogenic potentials to sound and vibration: characteristics in vestibular migraine that enable separation from M\u00e9ni\u00e8re's disease","volume":"32","author":"R L Taylor","year":"2012","journal-title":"Cephalalgia"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"594481","DOI":"10.3389\/fneur.2021.594481","article-title":"Endolymphatic hydrops in patients with vestibular migraine and concurrent M\u00e9ni\u00e8re's disease","volume":"12","author":"S Y Oh","year":"2021","journal-title":"Front Neurol"},{"issue":"08","key":"ref14","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1288\/00005537-198408000-00020","article-title":"M\u00e9ni\u00e8re's disease: a 30-year epidemiologic and clinical study in Rochester, Mn, 1951-1980","volume":"94","author":"P Wladislavosky-Waserman","year":"1984","journal-title":"Laryngoscope"},{"issue":"05","key":"ref15","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1016\/j.otohns.2005.06.015","article-title":"Prevalence of Meni\u00e8re's disease in general population of Southern Finland","volume":"133","author":"M Havia","year":"2005","journal-title":"Otolaryngol Head Neck Surg"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"879","DOI":"10.3389\/fneur.2020.00879","article-title":"Ocular vestibular-evoked myogenic potential amplitudes elicited at 4\u2009kHz optimize detection of superior semicircular canal dehiscence","volume":"11","author":"E D Tran","year":"2020","journal-title":"Front Neurol"},{"issue":"03","key":"ref17","doi-asserted-by":"crossref","first-page":"452","DOI":"10.3390\/audiolres11030042","article-title":"Investigating performance of cVEMP and oVEMP in the identification of superior canal dehiscence in relation to dehiscence location and size","volume":"11","author":"M Maheu","year":"2021","journal-title":"Audiology Res"},{"issue":"01","key":"ref18","doi-asserted-by":"crossref","first-page":"88","DOI":"10.4081\/audiores.2014.88","article-title":"Optimizing stimulus repetition rate for recording ocular vestibular evoked myogenic potential elicited by air-conduction tone bursts of 500\u2009Hz","volume":"4","author":"N K Singh","year":"2014","journal-title":"Audiology Res"},{"issue":"03","key":"ref19","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1044\/2015_AJA-15-0011","article-title":"The effect of repetition rate on air-conducted ocular vestibular evoked myogenic potentials (oVEMPs)","volume":"24","author":"J M Bogle","year":"2015","journal-title":"Am J Audiol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1044\/2019_AJA-IND50-18-0083","article-title":"A novel stimulation paradigm for obtaining interfrequency amplitude ratio of ocular vestibular evoked myogenic potentials","volume":"28","author":"N K Singh","year":"2019","journal-title":"Am J Audiol"},{"issue":"08","key":"ref22","doi-asserted-by":"crossref","first-page":"708","DOI":"10.3766\/jaaa.16071","article-title":"Safe use of acoustic vestibular-evoked myogenic potential stimuli: protocol and patient-specific considerations","volume":"28","author":"C DF Portnuff","year":"2017","journal-title":"J Am Acad Audiol"},{"issue":"03","key":"ref23","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1097\/AUD.0000000000000646","article-title":"Is there a safe level for recording vestibular evoked myogenic potential? Evidence from cochlear and hearing function tests","volume":"40","author":"N K Singh","year":"2019","journal-title":"Ear Hear"},{"volume-title":"ANSI S. 13: maximum permissible ambient noise audiometric testing","year":"1991","key":"ref24"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1044\/2019_AJA-IND50-18-0105","article-title":"Intersession variations in frequency tuning of ocular vestibular evoked myogenic potentials in healthy individuals","volume":"28","author":"N K Singh","year":"2019","journal-title":"Am J Audiol"},{"issue":"02","key":"ref26","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1037\/0033-2909.86.2.420","article-title":"Intraclass correlations: uses in assessing rater reliability","volume":"86","author":"P E Shrout","year":"1979","journal-title":"Psychol Bull"},{"issue":"04","key":"ref27","first-page":"299","article-title":"Vestibular evoked myogenic potentials: test-retest reliability","volume":"16","author":"M Versino","year":"2001","journal-title":"Funct Neurol"},{"issue":"07","key":"ref28","doi-asserted-by":"crossref","first-page":"469","DOI":"10.3766\/jaaa.22.7.7","article-title":"Effects of stimulus and recording parameters on the air conduction ocular vestibular evoked myogenic potential","volume":"22","author":"O D Murnane","year":"2011","journal-title":"J Am Acad Audiol"},{"issue":"16","key":"ref29","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1097\/WNR.0b013e3283329b4a","article-title":"Frequency tuning properties of ocular vestibular evoked myogenic potentials","volume":"20","author":"Y Chihara","year":"2009","journal-title":"Neuroreport"},{"issue":"05","key":"ref30","first-page":"491","article-title":"Frequency tuning in the tone burst-evoked myogenic potentials in extraocular muscles in normal human subjects","volume":"39","author":"A Lewis","year":"2010","journal-title":"J Otolaryngol Head Neck Surg"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/S0378-5955(99)00222-1","article-title":"A saccular origin of frequency tuning in myogenic vestibular evoked potentials?: implications for human responses to loud sounds","volume":"141","author":"N P Todd","year":"2000","journal-title":"Hear Res"},{"issue":"03","key":"ref32","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.neulet.2008.12.055","article-title":"A utricular origin of frequency tuning to low-frequency vibration in the human vestibular system?","volume":"451","author":"N P Todd","year":"2009","journal-title":"Neurosci Lett"},{"issue":"04","key":"ref33","doi-asserted-by":"crossref","first-page":"278","DOI":"10.3109\/00206097709071839","article-title":"Multifrequency tympanometry","volume":"16","author":"V Colletti","year":"1977","journal-title":"Audiology"},{"issue":"05","key":"ref34","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1097\/00003446-198409000-00003","article-title":"Tympanometry","volume":"5","author":"J E Shanks","year":"1984","journal-title":"Ear Hear"},{"issue":"05","key":"ref35","doi-asserted-by":"crossref","first-page":"245","DOI":"10.3109\/00206099409071884","article-title":"Multifrequency tympanometry. 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