{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T21:14:11Z","timestamp":1791666851000,"version":"4.3.4"},"reference-count":47,"publisher":"Georg Thieme Verlag KG","issue":"05","funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health [2]","doi-asserted-by":"crossref","award":["UL1TR001417"],"award-info":[{"award-number":["UL1TR001417"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["UL1TR001449"],"award-info":[{"award-number":["UL1TR001449"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:p>\n            Objective\u2003This study aimed to examine the association between maternal hypertension (HTN) exposure and neonatal acute kidney injury (AKI).<\/jats:p><jats:p>\n            Study Design\u2003Retrospective cohort study of 2,162 neonates admitted to 24 neonatal intensive care units (NICUs). Neonates were classified into the following exposure groups: any maternal HTN, chronic maternal HTN, preeclampsia\/eclampsia, both, or neither. Demographics, clinical characteristics, and AKI status were compared using Chi-square and analysis of variance. General estimating logistic regression was used to estimate adjusted odds ratios and included a stratified analysis for site of delivery.<\/jats:p><jats:p>\n            Result\u2003Neonates exposed to any maternal HTN disorder had a tendency toward less overall and early AKI. When stratified by inborn versus outborn, exposure to both maternal HTN disorders was associated with a significantly reduced odds of early AKI only in the inborn neonates.<\/jats:p><jats:p>\n            Conclusion\u2003Exposure to maternal HTN, especially preeclampsia\/eclampsia superimposed on chronic HTN, was associated with less likelihood of early AKI in the inborn group.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/a-1780-2249","type":"journal-article","created":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T23:57:28Z","timestamp":1645660648000},"page":"649-659","source":"Crossref","is-referenced-by-count":8,"title":["Maternal Hypertension Disorders and Neonatal Acute Kidney Injury: Results from the AWAKEN Study"],"prefix":"10.1055","volume":"41","clinical-trial-number":[{"clinical-trial-number":"nct02443389","registry":"10.18810\/clinical-trials-gov"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9331-1905","authenticated-orcid":false,"given":"Marissa J.","family":"DeFreitas","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Pediatric Nephrology, University of Miami\/Holtz Children's Hospital, Miami, Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Russell","family":"Griffin","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, University of Alabama Birmingham, Birmingham, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keia","family":"Sanderson","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Nephrology and Hypertension, University of North Carolina, Chapel Hill, North 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Einstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Children's National Medical Center","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Golisano Children's Hospital University of Rochester","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"(currently Union Hospital, Terre Haute)","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Maimonides Medical Center","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"McGill University","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Medanta, Medicity The Cradle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Metrohealth Medical 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