{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T09:34:52Z","timestamp":1761989692715},"reference-count":19,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T00:00:00Z","timestamp":1664150400000},"content-version":"vor","delay-in-days":268,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ultrasound Int Open"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Purpose Transabdominal ultrasound (US) and magnetic resonance enterography\n                    (MRE) are used to assess disease activity and extent in IBD, but their impact on\n                    therapeutic decisions is unclear. Therefore, our study has two goals: to compare\n                    the usefulness of US and MRE in assessing disease extent and activity in the\n                    small and large bowel, and to determine the relevance for clinical decisions in\n                    IBD.<\/jats:p><jats:p>\n          Materials and Methods We included 54 IBD patients who had undergone both\n                    MRE and US within three months. We used the construct reference standard model\n                    to compare MRE and US for detecting inflammation and examined the impact on\n                    clinical decisions in IBD patients.<\/jats:p><jats:p>\n          Results In 54 IBD patients (44 patients Crohn\u2019s disease (CD), 5\n                    ulcerative colitis (UC), 5 indeterminate colitis (IC)), 42 patients\n                    (77.8%) showed inflammation either in the small or large bowel. Small\n                    bowel disease was present in 34 patients (77.3%). Complications were\n                    found in 19 patients (35.2%). MRE and US both showed high sensitivity\n                    (90.5 and 88.1%) and moderate specificity (50% in MRE and US)\n                    for detecting inflammation. MRE revealed higher sensitivity than US for\n                    detecting conglomerate tumors without statistical significance (85.7 vs.\n                    71.4%, p=1.0) and equal specificity (97.9 vs 97.7,\n                    p=1.0). Therapeutic decisions included steroids in 20 patients\n                    (47.6%) and surgery\/percutaneous drainage in six patients\n                    (14.3%), these decisions were triggered by results of US or MRE in equal\n                    distribution.<\/jats:p><jats:p>\n          Conclusion US and MRE have comparable sensitivity and specificity for\n                    detecting intestinal inflammation and complications in IBD patients. Therefore,\n                    both methods are sufficient for making clinical decisions.<\/jats:p>","DOI":"10.1055\/a-1781-4410","type":"journal-article","created":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T23:08:21Z","timestamp":1664233701000},"page":"E22-E28","source":"Crossref","is-referenced-by-count":8,"title":["Transabdominal Ultrasound and Magnetic Resonance Enterography in\n                    Inflammatory Bowel Disease: Results of an Observational Retrospective\n                    Single-Center Study"],"prefix":"10.1055","volume":"08","author":[{"given":"Lenika","family":"Calavrezos","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Gastroenterology, University\n                    Medical Center Hamburg-Eppendorf, Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Bannas","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology and Nuclear\n                    Medicine, University Medical Center Hamburg-Eppendorf Center for Diagnostics,\n                    Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malte","family":"Warncke","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology and Nuclear\n                    Medicine, University Medical Center Hamburg-Eppendorf Center for Diagnostics,\n                    Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christiane","family":"Wiegard","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Gastroenterology, University\n                    Medical Center Hamburg-Eppendorf, Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Huber","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Gastroenterology, University\n                    Medical Center Hamburg-Eppendorf, Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolin","family":"Manthey","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Gastroenterology, University\n                    Medical Center Hamburg-Eppendorf, Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,9,26]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1038\/ajg.2015.233","article-title":"Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE):\n                    Determining Therapeutic Goals for Treat-to-Target","volume":"110","author":"L Peyrin-Biroulet","year":"2015","journal-title":"The American journal of gastroenterology"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1038\/s41572-020-0205-x","article-title":"Ulcerative colitis","volume":"6","author":"T 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Bryant","year":"2018","journal-title":"Gut"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.crohns.2013.02.020","article-title":"Imaging techniques for assessment of inflammatory bowel disease: joint ECCO and\n                    ESGAR evidence-based consensus guidelines","volume":"7","author":"J Panes","year":"2013","journal-title":"Journal of Crohn\u2019s & colitis"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1111\/jgh.14908","article-title":"Magnetic resonance enterography for predicting the clinical course of\n                    Crohn\u2019s disease strictures","volume":"35","author":"J D Schulberg","year":"2020","journal-title":"Journal of gastroenterology and hepatology"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1093\/ecco-jcc\/jjy093","article-title":"Comparative Accuracy of Bowel Ultrasound Versus Magnetic Resonance Enterography\n                    in Combination With Colonoscopy in Assessing Crohn\u2019s Disease and Guiding\n                    Clinical Decision-making","volume":"12","author":"M Allocca","year":"2018","journal-title":"Journal of Crohn\u2019s & colitis"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1055\/s-0042-115853","article-title":"EFSUMB Recommendations and Guidelines for Gastrointestinal Ultrasound","volume":"38","author":"K Nylund","year":"2017","journal-title":"Ultraschall in Med"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1007\/s00330-014-3503-4","article-title":"Magnetic resonance enterography for assessment of intestinal graft-versus-host\n                    disease after allogeneic stem cell transplantation","volume":"25","author":"T Derlin","year":"2015","journal-title":"Eur Radiol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"iii","DOI":"10.3310\/hta11500","article-title":"Evaluation of diagnostic tests when there is no gold standard. A review of\n                    methods","volume":"11","author":"A W Rutjes","year":"2007","journal-title":"Health Technol Assess"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.1007\/s003300101065","article-title":"Ultrasonography of chronic inflammatory bowel diseases","volume":"11","author":"P J Valette","year":"2001","journal-title":"European radiology"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2020.08.005:","article-title":"Bowel contrast-enhanced ultrasound perfusion imaging in the evaluation of\n                    Crohn\u2019s disease patients undergoing anti-TNFalpha therapy","author":"L Laterza","year":"2020","journal-title":"Digestive and liver disease: official journal of the Italian Society\n                    of Gastroenterology and the Italian Association for the Study of the\n                    Liver"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.ejrad.2008.10.029","article-title":"The diagnostic value of small bowel wall vascularity after sulfur\n                    hexafluoride-filled microbubble injection in patients with Crohn\u2019s\n                    disease. Correlation with the therapeutic effectiveness of specific\n                    anti-inflammatory treatment","volume":"69","author":"E Quaia","year":"2009","journal-title":"European journal of radiology"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1016\/S2468-1253(18)30161-4","article-title":"Diagnostic accuracy of magnetic resonance enterography and small bowel\n                    ultrasound for the extent and activity of newly diagnosed and relapsed\n                    Crohn\u2019s disease (METRIC): a multicentre trial","volume":"3","author":"S A Taylor","year":"2018","journal-title":"The lancet Gastroenterology & hepatology"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1136\/gutjnl-2019-319451","article-title":"Intestinal ultrasound for monitoring therapeutic response in patients with\n                    ulcerative colitis: results from the TRUST&UC study","volume":"69","author":"C Maaser","year":"2020","journal-title":"Gut"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1093\/ecco-jcc\/jjy113","article-title":"ECCO-ESGAR Guideline for Diagnostic Assessment in IBD Part 1: Initial diagnosis,\n                    monitoring of known IBD, detection of complications","volume":"13","author":"C Maaser","year":"2019","journal-title":"Journal of Crohn\u2019s & colitis"}],"container-title":["Ultrasound International Open"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1781-4410.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T23:08:40Z","timestamp":1664233720000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1781-4410"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":19,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2022,5,3]]},"published-print":{"date-parts":[[2022,1]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1781-4410","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2509-596X","2199-7152"],"issn-type":[{"value":"2509-596X","type":"print"},{"value":"2199-7152","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1]]}}}