{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,6,16]],"date-time":"2022-06-16T00:41:53Z","timestamp":1655340113662},"reference-count":20,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Monbl Augenheilkd"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Hintergrund Untersuchung der langfristigen Effizienz und Sicherheit der transskleralen Lasertherapie (TLT) mittels MicroPulse \u00fcber 24 Monate bei Patienten mit prim\u00e4rem\n\t\t\t\t\tOffenwinkelglaukom (POWG).<\/jats:p><jats:p>\n          Material und Methoden In dieser prospektiven interventionellen Fallserie wurden die Daten von 44 Augen von medikament\u00f6s behandelten POWG-Patienten ausgewertet, die eine\n\t\t\t\t\tMicroPulse-TLT erhielten, um eine weitere Senkung des Augeninnendrucks (IOD) zu erreichen. Es wurden die Reduktion des 24-h-IODs, der zirkadianen IOD-Fluktuationen und der IOD-Spitzen nach\n\t\t\t\t\t3, 12 und 24 Monaten untersucht. Zudem sollten postoperative Komplikationen, die Misserfolgsquote und Einflussfaktoren auf den Therapieerfolg analysiert werden.<\/jats:p><jats:p>\n          Ergebnisse Der IOD ist von 16,1\u2009\u00b1\u20093,4\u2009mmHg pr\u00e4operativ auf 13,0\u2009\u00b1\u20092,9\u2009mmHg (n\u2009=\u200931; p\u2009&lt;\u20090,001) nach 3 Monaten, 12,3\u2009\u00b1\u20093,0\u2009mmHg (n\u2009=\u200927; p\u2009&lt;\u20090,001) nach 12 Monaten und\n\t\t\t\t\t13,1\u2009\u00b1\u20092,6\u2009mmHg (n\u2009=\u200923; p\u2009&lt;\u20090,001) nach 24 Monaten gesunken. Nach 24 Monaten erreichten 23 Augen (52%) ihren individuellen Zieldruck. Es traten keine schwerwiegenden postoperativen\n\t\t\t\t\tKomplikationen auf. Es konnten keine Einflussfaktoren auf den Therapieerfolg identifiziert werden. Das h\u00e4ufigste Therapieversagen war innerhalb der ersten 3 postoperativen Monate zu\n\t\t\t\t\tbeobachten und blieb danach nahezu stabil.<\/jats:p><jats:p>\n          Schlussfolgerung Die MicroPulse-TLT zeigt eine gute IOD-Senkung bei Patienten mit prim\u00e4rem Offenwinkelglaukom und maximal tolerierter drucksenkender Lokaltherapie, wobei etwa 50% der\n\t\t\t\t\tAugen ihren individuellen Zieldruck erreichten.<\/jats:p>","DOI":"10.1055\/a-1782-7941","type":"journal-article","created":{"date-parts":[[2022,4,15]],"date-time":"2022-04-15T00:41:35Z","timestamp":1649983295000},"page":"786-792","source":"Crossref","is-referenced-by-count":0,"title":["2-Jahres-Ergebnisse nach transskleraler MicroPulse-Lasertherapie bei Patienten mit prim\u00e4rem Offenwinkelglaukom"],"prefix":"10.1055","volume":"239","author":[{"given":"S\u00f6ren","family":"Waibel","sequence":"additional","affiliation":[{"name":"Augenklinik, Universit\u00e4tsklinikum Carl Gustav Carus, Dresden, 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