{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:26:20Z","timestamp":1787498780714,"version":"build-2736575974"},"reference-count":32,"publisher":"Georg Thieme Verlag KG","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:p>Objective\u2003The objective of our study was to compare the maternal and neonatal complications of periviable birth by the delivery route.<\/jats:p>\n                  <jats:p>Study Design\u2003A retrospective cohort study of periviable deliveries (220\/7\u2013256\/7weeks) from 2013 to 2020 at a tertiary teaching institution was conducted. Deliveries were grouped by the mode of delivery. Excluded deliveries included pregnancy termination, anomaly, or undesired neonatal resuscitation. The primary composite maternal outcome included death, intensive care admission, sepsis, surgical site infection, unplanned operation, or readmission. Secondary outcomes included maternal blood loss, length of stay, neonatal survival, bronchopulmonary dysplasia (BPD), intraventricular hemorrhage (IVH), necrotizing enterocolitis (NEC), patent ductus arteriosus (PDA), and retinopathy of prematurity (ROP). Outcomes were compared using Student's t-test, Wilcoxon\u2013Mann\u2013Whitney and Chi-squared tests. Relative risk (RR) and 95% confidence intervals were calculated with log-binomial regression. p-Values &lt;0.05 were considered significant. Demographic and intervention variables associated with the outcome and the exposure were included in an adjusted relative risk (aRR) model. Subgroup analyses of singleton pregnancies and 220\/7 to 236\/7 weeks deliveries were conducted.<\/jats:p>\n                  <jats:p>Results\u2003After exclusion, 230 deliveries were included in the cohort. Maternal characteristics were similar between cohorts. For the primary outcome, cesarean delivery was associated with a trend toward increased maternal morbidity (22.6 vs. 10.7%, RR\u2009=\u20092.11 [1.03\u20134.43], aRR\u2009=\u20091.95 [0.94\u20134.03], p-value 0.07). Administration of magnesium sulfate, antenatal corticosteroids, and tocolytics were similar between cohorts. Neonatal survival to discharge was not different between the groups (54\/83, 65.1% vs. 118\/191, 61.8%, aRR\u2009=\u20090.93 [0.77\u20131.13]). Among the 172 neonates discharged alive, there was no difference in BPD, IVH, NEC, PDA, ROP, or intact survival.<\/jats:p>\n                  <jats:p>Conclusion\u2003Periviable birth has a high rate of maternal morbidity with a trend toward the highest risk among women undergoing cesarean delivery. These risks should be included in shared decision-making.<\/jats:p>\n                  <jats:p>Key Points<\/jats:p>","DOI":"10.1055\/a-1788-5802","type":"journal-article","created":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T02:18:57Z","timestamp":1646619537000},"page":"1269-1278","source":"Crossref","is-referenced-by-count":17,"title":["The Impact of Mode of Delivery on Maternal and Neonatal Outcomes during Periviable Birth (22\u201325 Weeks)"],"prefix":"10.1055","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0770-7477","authenticated-orcid":false,"given":"Jared T.","family":"Roeckner","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, University of South Florida Morsani College of Medicine and Tampa General Hospital, Tampa, Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erica","family":"Peterson","sequence":"additional","affiliation":[{"name":"Division of Neonatology, University of South Florida Morsani College of Medicine, Tampa General Hospital, Tampa, Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Rizzo","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, University of South Florida Morsani College of Medicine and Tampa General Hospital, Tampa, Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaime","family":"Flores-Torres","sequence":"additional","affiliation":[{"name":"Division of Neonatology, University of South Florida Morsani College of Medicine, Tampa General Hospital, Tampa, Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony O.","family":"Odibo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose R.","family":"Duncan","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, University of South Florida Morsani College of Medicine and Tampa General Hospital, Tampa, Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,5,31]]},"reference":[{"issue":"01","key":"ref1","doi-asserted-by":"crossref","first-page":"70.e1","DOI":"10.1016\/j.ajog.2015.03.002","article-title":"Morbidity and mortality associated with mode of delivery for breech periviable deliveries","volume":"213","author":"B T Edmonds","year":"2015","journal-title":"Am J Obstet Gynecol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.jpeds.2019.08.028","article-title":"Outcomes at 18 to 22 months of corrected age for infants born at 22 to 25 weeks of gestation in a center practicing active management","volume":"217","author":"P L Watkins","year":"2020","journal-title":"J 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