{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T22:28:16Z","timestamp":1788560896634,"version":"build-2803163510"},"reference-count":12,"publisher":"Georg Thieme Verlag KG","issue":"05","license":[{"start":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T00:00:00Z","timestamp":1650585600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fortschr Neurol Psychiatr"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Sialorrhoe, ein unkontrollierter, \u00fcberm\u00e4\u00dfiger\n                    Speichelfluss aus dem Mund und in den Schlund, tritt als Begleitsymptom bei\n                    verschiedenen, v.\u2009a. neurologischen Erkrankungen im Kindes- und\n                    Erwachsenenalter auf. Mit IncobotulinumtoxinA (Xeomin, IncoBoNT\/A,\n                    Merz Pharmaceuticals GmbH) steht seit 2019 ein zugelassenes Medikament\n                    f\u00fcr die Behandlung der Sialorrhoe zur Verf\u00fcgung.\n                    Indikationsstellung, m\u00f6gliche Therapieziele, Praxis der Behandlung und\n                    Management in besonderen Behandlungssituationen bilden den Schwerpunkt dieser\n                    konsentierten Praxis-Empfehlungen, die in interdisziplin\u00e4rer\n                    Zusammenarbeit erfahrener Anwender entwickelt wurden. Ziel ist, den Zugang zur\n                    Therapie zu erleichtern und einen Beitrag zu einer qualifizierten\n                    Botulinumtoxin-Therapie zu leisten.<\/jats:p>","DOI":"10.1055\/a-1802-6006","type":"journal-article","created":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T22:52:26Z","timestamp":1650667946000},"page":"212-221","source":"Crossref","is-referenced-by-count":5,"title":["Behandlung der Sialorrhoe mit Botulinum Neurotoxin Typ A \u2013\n                    Konsentierte Praxisempfehlungen f\u00fcr Kinder und\n                    Erwachsene"],"prefix":"10.1055","volume":"90","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8574-3297","authenticated-orcid":false,"given":"Wolfgang H.","family":"Jost","sequence":"additional","affiliation":[{"name":"Parkinson-Klinik Ortenau, Wolfach, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"B\u00e4umer","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr 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Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8540-3789","authenticated-orcid":false,"given":"Carsten","family":"Buhmann","sequence":"additional","affiliation":[{"name":"Neurologie, Universitatsklinikum Hamburg-Eppendorf, Hamburg,\n                    Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Grosheva","sequence":"additional","affiliation":[{"name":"HNO-Uniklinik K\u00f6ln, Universit\u00e4t zu K\u00f6ln,\n                    Medizinische Fakult\u00e4t, K\u00f6ln, Deutschland Department of\n                    Otorhinolaryngology, Head and Neck Surgery, University of Cologne, Medical\n                    Faculty, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orlando","family":"Guntinas-Lichius","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-, Nasen- Ohrenheilkunde,\n                    Universit\u00e4tsklinikum Jena, Jena, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ute","family":"Mlynczak","sequence":"additional","affiliation":[{"name":"UniReha GmbH, Klinik und Poliklinik f\u00fcr HNO-Heilkunde, Kopf-\n                    und Halschirurgie, Uniklinik K\u00f6ln, K\u00f6ln, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Paus","sequence":"additional","affiliation":[{"name":"Fachabteilung Neurologie, GFO Kliniken Troisdorf, Troisdorf,\n                    Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Pflug","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr H\u00f6r-, Stimm- und\n                    Sprachheilkunde, Universit\u00e4tsklinikum Hamburg-Eppendorf, Hamburg,\n                    Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Schr\u00f6der","sequence":"additional","affiliation":[{"name":"P\u00e4diatrische Neurologie, Entwicklungsneurologie, iSPZ, Dr. von\n                    Haunersches Kinderspital, Klinikum der Universit\u00e4t M\u00fcnchen,\n                    M\u00fcnchen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armin","family":"Steffen","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr HNO-Heilkunde, Universit\u00e4t zu\n                    L\u00fcbeck\/UKSH Campus L\u00fcbeck, L\u00fcbeck,\n                    Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernd","family":"Wilken","sequence":"additional","affiliation":[{"name":"Neurop\u00e4diatrie mit Sozialp\u00e4diatrischem Zentrum,\n                    Klinikum Kassel, Kassel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steffen","family":"Berweck","sequence":"additional","affiliation":[{"name":"Fachzentrum f\u00fcr P\u00e4diatrische Neurologie,\n                    Neurorehabilitation und Epileptologie, Sch\u00f6n Klinik, Vogtareuth,\n                    Vogtareuth, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,4,22]]},"reference":[{"key":"ref2","first-page":"90","article-title":"Therapie der Sialorrhoe mit Botulinumtoxin ein Update","author":"W H Jost","year":"2022","journal-title":"Fortschr Neurol Psychiatr"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000007368","article-title":"SIAXI: placebo-controlled, randomized, double-blind study of incobotulinumtoxinA\n                    for sialorrhea","author":"W H 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