{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T16:44:59Z","timestamp":1755794699856},"reference-count":30,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Orthop Unfall"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background Raised complication rates have been reported for total hip arthroplasty (THA) in posttraumatic hip joints after acetabular fractures with prior open reduction and internal\n          fixation (ORIF). The present study evaluated (I) postoperative surgical site infection and the risk of early infection following THA in posttraumatic hip joints after acetabular fractures\n          and (II) the discriminatory ability of preoperative C-reactive protein (CRP) blood levels for periprosthetic joint infection (PJI).<\/jats:p><jats:p>\n          Materials and Methods Patients were included who had undergone THA (2014\u20132019) after prior ORIF, and nonsurgically treated acetabular fractures. Patients\u2019 demographics and the\n          duration between fracture and THA implantation were assessed. Preoperative diagnostic testing (laboratory results, hip aspirations) as well as the results of intraoperative microbiological\n          swabs and sonication were also evaluated. Postoperative complications were recorded.<\/jats:p><jats:p>\n          Results Sixty-seven patients (51 men\/16 women) were included, with a mean age of 54.7\u00a0\u00b1\u00a014.0 years (range: 18.0\u201382.9). The mean time between acetabular fracture and THA was\n          13.5\u00a0\u00b1\u00a014.9 years (0.2\u201353.5). Four subgroups were classified: subgroup I (nonsurgical, n\u00a0=\u00a015), subgroup II (complete removal of osteosynthesis, n\u00a0=\u00a08), subgroup III (partial removal of\n          osteosynthesis, n\u00a0=\u00a015), and subgroup IV (remaining osteosynthesis, n\u00a0=\u00a029). Preoperative CRP blood levels were normal. CRP levels had no discriminatory ability to predict PJI (AUC: 0.43).\n          Positive microbiological swabs were assessed in subgroups III (n\u00a0=\u00a01) and IV (n\u00a0=\u00a02). Complications during follow-up occurred in subgroups I (one aseptic loosening [6.7%]), III (one wound\n          revision [6.7%], two low-grade infections [13.3%]), and IV (three low-grade infections [10.3%]).<\/jats:p><jats:p>\n          Conclusion High infection rates were found in patients with THA after acetabular fracture with remaining implants or partial implant removal. Serum CRP alone seems to be a poor\n          predictor. Therefore, an extensive diagnostic algorithm can help to detect an occult infection, including preoperative hip aspiration (microbiological samples and measurements of synovial\n          CRP, WBC, and alpha-defensin levels). Intraoperative tissue samples and sonication results should be obtained during THA implantation.<\/jats:p>","DOI":"10.1055\/a-1810-7379","type":"journal-article","created":{"date-parts":[[2022,5,23]],"date-time":"2022-05-23T23:25:16Z","timestamp":1653348316000},"page":"671-677","source":"Crossref","is-referenced-by-count":2,"title":["Risk of Periprosthetic Joint Infection after Posttraumatic Hip Arthroplasty following Acetabular Fractures"],"prefix":"10.1055","volume":"161","author":[{"given":"Florian","family":"Schmidutz","sequence":"additional","affiliation":[{"name":"Department of Traumatology and Reconstructive Surgery, Berufsgenossenschaftliche Unfallklinik T\u00fcbingen, T\u00fcbingen, Germany"},{"name":"Department of Orthopaedic Surgery, Physical Medicine and Rehabilitation, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen, M\u00fcnchen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna Janine","family":"Schreiner","sequence":"additional","affiliation":[{"name":"Department of Traumatology and Reconstructive Surgery, Berufsgenossenschaftliche Unfallklinik T\u00fcbingen, T\u00fcbingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc-Daniel","family":"Ahrend","sequence":"additional","affiliation":[{"name":"Department of Traumatology and Reconstructive Surgery, Berufsgenossenschaftliche Unfallklinik T\u00fcbingen, T\u00fcbingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich","family":"St\u00f6ckle","sequence":"additional","affiliation":[{"name":"Center for Musculoskeletal Surgery (CMSC), Charite University Hospital Berlin, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sven","family":"Maier","sequence":"additional","affiliation":[{"name":"Department of Traumatology and Reconstructive Surgery, Berufsgenossenschaftliche Unfallklinik T\u00fcbingen, T\u00fcbingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tina","family":"Histing","sequence":"additional","affiliation":[{"name":"Department of Traumatology and Reconstructive Surgery, Berufsgenossenschaftliche Unfallklinik T\u00fcbingen, T\u00fcbingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Hemmann","sequence":"additional","affiliation":[{"name":"Department of Traumatology and Reconstructive Surgery, Berufsgenossenschaftliche Unfallklinik T\u00fcbingen, T\u00fcbingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,5,23]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1302\/0301-620X.87B7.16017","article-title":"Acetabular fractures: a 16-year prospective epidemiological study","volume":"87","author":"A Laird","year":"2005","journal-title":"J Bone Joint Surg Br"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1097\/BOT.0000000000000576","article-title":"Achieving Anatomic Acetabular Fracture Reduction-When is the Best Time to Operate?","volume":"30","author":"SK Dailey","year":"2016","journal-title":"J Orthop Trauma"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1049","DOI":"10.1007\/s00590-019-02406-6","article-title":"Total hip arthroplasty for the treatment of osteoarthritis secondary to acetabular fractures treated by open reduction and internal fixation","volume":"29","author":"P Dawson","year":"2019","journal-title":"Eur J Orthop Surg Traumatol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"2167","DOI":"10.1007\/s00264-018-4169-3","article-title":"Predictors for secondary hip osteoarthritis after acetabular fractures-a pelvic registry study","volume":"43","author":"MF Rollmann","year":"2019","journal-title":"Int Orthop"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1302\/0301-620X.87B1.15605","article-title":"Operative treatment of displaced fractures of the acetabulum. 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Unfallchirurgie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1810-7379.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,5]],"date-time":"2023-12-05T00:15:32Z","timestamp":1701735332000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1810-7379"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,23]]},"references-count":30,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2023,12,4]]},"published-print":{"date-parts":[[2023,12]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1810-7379","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1864-6697","1864-6743"],"issn-type":[{"value":"1864-6697","type":"print"},{"value":"1864-6743","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,23]]}}}