{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T10:52:31Z","timestamp":1784199151114,"version":"3.55.0"},"reference-count":33,"publisher":"Georg Thieme Verlag KG","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rofo"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:p>\n            Background\u2002Ultrasound is one of the most important imaging methods in the daily routine. Contrast-enhanced ultrasound (CEUS) has put ultrasound on equal footing with computed tomography and magnetic resonance imaging in many areas. Although ultrasound contrast agents are commonly administered intravenously, endocavitary application as performed in the case of iodine-containing contrast agents is also possible.<\/jats:p><jats:p>\n            Method\u2002Based on the current literature, this overview provides information regarding possible endocavitary applications of ultrasound contrast agents as they are used and could be used in the daily routine in radiology. Examples are provided to illustrate the advantages and disadvantages of clinical use.<\/jats:p><jats:p>\n            Results and Conclusion\u2002Endocavitary CEUS broadens the spectrum of possible ultrasound applications and can be safely used for patient diagnosis and treatment. The method can be safely used for diagnosis and patient management, particularly in patients in whom examinations including exposure to radiation with iodine-containing contrast agents may be contraindicated and who have limited mobility due to disease severity.<\/jats:p><jats:p>\n            Key points:\u2002<\/jats:p><jats:p>\n            Citation Format\n          <\/jats:p>","DOI":"10.1055\/a-1826-0325","type":"journal-article","created":{"date-parts":[[2022,8,17]],"date-time":"2022-08-17T23:11:03Z","timestamp":1660777863000},"page":"1204-1215","source":"Crossref","is-referenced-by-count":5,"title":["Endocavitary Contrast-Enhanced Ultrasound"],"prefix":"10.1055","volume":"194","author":[{"given":"Kurt","family":"Vollert","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr diagnostische und interventionelle Radiologie und Neuroradiologie, Universit\u00e4tsklinikum Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk Andre","family":"Clevert","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Klinische Radiologie, Campus Grosshadern, Klinikum der Universit\u00e4t M\u00fcnchen, Munchen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timm","family":"Kleffel","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr diagnostische und interventionelle Radiologie und Neuroradiologie, Universit\u00e4tsklinikum Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,8,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1055\/a-1177-0530","article-title":"Guidelines and Good Clinical Practice Recommendations for Contrast Enhanced Ultrasound (CEUS) in the Liver \u2013 Update 2020","volume":"41","author":"C F Dietrich","year":"2020","journal-title":"Ultraschall in Med"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"e2","DOI":"10.1055\/a-0586-1107","article-title":"The EFSUMB Guidelines and Recommendations for the Clinical Practice of Contrast-Enhanced Ultrasound (CEUS) in Non-Hepatic Applications: Update 2017 (Long Version)","volume":"39","author":"P S Sidhu","year":"2018","journal-title":"Ultraschall in Med"},{"issue":"08","key":"ref3","doi-asserted-by":"publisher","first-page":"1995","DOI":"10.1007\/s00330-007-0623-0","article-title":"Microbubble ultrasound contrast agents: an update","volume":"17","author":"E Quaia","year":"2007","journal-title":"Eur Radiol"},{"issue":"03","key":"ref4","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.ejrad.2006.06.022","article-title":"Ultrasound contrast agents: an overview","volume":"60","author":"D Cosgrove","year":"2006","journal-title":"Eur J Radiol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0720-048X(99)00150-3","article-title":"Vesico-ureteral reflux: diagnosis and staging with voiding color Doppler US: preliminary experience","volume":"35","author":"R Farina","year":"2000","journal-title":"Eur J Radiol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1016\/j.ultrasmedbio.2006.05.031","article-title":"The safety of Sonovue in abdominal applications: retrospective analysis of 23188 investigations","volume":"32","author":"F Piscaglia","year":"2006","journal-title":"Ultrasound Med Biol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1055\/s-0033-1335546","article-title":"Der endocavit\u00e4re Kontrastmittelultraschall-verschiedene Anwendungen, eine \u00dcbersicht \u00fcber die Literatur und zuk\u00fcnftige Perspektiven","volume":"34","author":"A Ignee","year":"2013","journal-title":"Ultraschall in Med"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1148\/rg.2017160123","article-title":"Contrast-enhanced US\u2013guided Interventions: Improving Success Rate and Avoiding Complications Using US Contrast Agents","volume":"37","author":"D Y Huang","year":"2017","journal-title":"RadioGraphics"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"960","DOI":"10.1007\/s00261-018-1473-8","article-title":"Contrast-enhanced ultrasound (CEUS) in abdominal intervention","volume":"43","author":"D Y Huang","year":"2018","journal-title":"Abdom Radiol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1007\/s00247-007-0529-7","article-title":"Voiding urosonography with ultrasound contrast agents for the diagnosis of vesicoureteric reflux in children. 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