{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:14:18Z","timestamp":1787004858980,"version":"build-2736575974"},"reference-count":113,"publisher":"Georg Thieme Verlag KG","issue":"09","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Clin Endocrinol Diabetes"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Mild autonomous cortisol secretion (mACS) is a state of cortisol excess usually\n                    associated with existence of adrenal incidentaloma. Because of the lack of\n                    symptoms of the disease, the biochemical evaluation is the most important to\n                    determine a diagnosis. However, scientific societies have different diagnostic\n                    criteria for mACS, which makes the treatment of this disease and using results\n                    of original papers in daily practice more difficult. Chronic hypercortisolemic\n                    state, even if mild, may lead to diseases that are mostly connected with overt\n                    Cushing\u2019s syndrome. Some of them can cause a higher mortality of\n                    patients with mACS and those problems need to be addressed. In this review we\n                    describe the comorbidities associated with mACS: cardiovascular disorders,\n                    arterial hypertension, diabetes mellitus, insulin resistance, dyslipidemia,\n                    obesity, metabolic syndrome, non-alcoholic fatty liver disease, vertebral\n                    fractures and osteoporosis. The point of this paper is to characterise them and\n                    determine if and how these conditions should be managed. Two databases \u2013\n                    PubMed and Web of Science were searched. Even though the evidence are scarce,\n                    this is an attempt to lead clinicians through the problems associated with this\n                    enigmatic condition.<\/jats:p>","DOI":"10.1055\/a-1827-4113","type":"journal-article","created":{"date-parts":[[2022,7,11]],"date-time":"2022-07-11T18:46:40Z","timestamp":1657565200000},"page":"567-576","source":"Crossref","is-referenced-by-count":19,"title":["Comorbidities in Mild Autonomous Cortisol Secretion \u2013 A\n                    Clinical Review of Literature"],"prefix":"10.1055","volume":"130","author":[{"given":"Aleksandra","family":"Czapla-Iskrzycka","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Internal Medicine, Faculty of Medicine,\n                    Medical University of Gda\u0144sk, Gda\u0144sk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata","family":"\u015awi\u0105tkowska-Stodulska","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Internal Medicine, Faculty of Medicine,\n                    Medical University of Gda\u0144sk, Gda\u0144sk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krzysztof","family":"Sworczak","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Internal Medicine, Faculty of Medicine,\n                    Medical University of Gda\u0144sk, Gda\u0144sk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,7,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1111\/cen.13145","article-title":"New diagnostic criteria for subclinical hypercortisolism using postsurgical\n                    hypocortisolism: The co-work of Adrenal Research study","volume":"86","author":"SH Lee","year":"2017","journal-title":"Clin 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