{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T04:22:01Z","timestamp":1769833321472,"version":"3.49.0"},"reference-count":33,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Horm Metab Res"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Subacute thyroiditis (SAT) developed after SARS-CoV-2 vaccines has been less studied. We aimed to compare classical SAT and SAT developed after SARS-CoV-2 vaccines in the context of clinical aspects. Adults with SAT detected in 90 days of COVID-19 vaccination (CoronaVac or Pfizer\/BioNTech) were grouped as Vac-SAT. Those with a history of SARS-CoV-2 or upper respiratory tract infection in 6 months before the vaccination, or vaccination with another antiviral vaccine after COVID-19 vaccination were excluded. Those with SAT detected before COVID-19 pandemic were grouped as Classical-SAT. Of total (n=85), female\/male (54\/31) ratio and age [43 (23\u201365)] were similar in Vac-SAT (n=23) and Classical-SAT (n=62). Duration between vaccine and SAT was 45 (7\u201390) days, and similar in CoronaVac-SAT (n=5) and BioNTech-SAT (n=18). SAT-duration was 28 (10\u2013150) days, and higher in Vac-SAT than in Classical-SAT (p=0.023). SAT was developed after the 1st dose vaccine in minority in CoronaVac-SAT (n=2) and BioNTech-SAT (n=3) (p=0.263). Previous LT4 use, and TSH elevation after resolution were more frequent in Vac-SAT than in Classical-SAT (p=0.027 and p=0.041). We included a considerable number of patients with SAT occurred after COVID-19 vaccines. We cannot provide clear evidence regarding the association of COVID-19 vaccines with SAT. SAT associated with CoronaVac or BioNTech seems unlikely to be occurred after the 1st dose, and to have a longer duration, more likely to be associated with previous LT4 use and lead TSH elevation after resolution than Classical-SAT. TSH should be followed-up after the resolution of SAT detected after COVID-19 vaccination.<\/jats:p>","DOI":"10.1055\/a-1840-4374","type":"journal-article","created":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T23:40:30Z","timestamp":1651448430000},"page":"380-388","source":"Crossref","is-referenced-by-count":9,"title":["Differences in Clinical Aspects Between Subacute Thyroiditis Associated with COVID-19 Vaccines and Classical Subacute Thyroiditis"],"prefix":"10.1055","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3703-416X","authenticated-orcid":false,"given":"\u00d6mercan","family":"Topalo\u011flu","sequence":"additional","affiliation":[{"name":"Endocrinology, Zonguldak B\u00fclent Ecevit University Faculty of Medicine, Zonguldak, Turkey"},{"name":"Obesity and Diabetes Practice and Research Center, Zonguldak B\u00fclent Ecevit University, Zonguldak, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sakin","family":"Tekin","sequence":"additional","affiliation":[{"name":"Endocrinology, Zonguldak B\u00fclent Ecevit University Faculty of Medicine, Zonguldak, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seda Nur","family":"Topalo\u011flu","sequence":"additional","affiliation":[{"name":"Internal Medicine, Zonguldak Bulent Ecevit Universitesi Tip Fakultesi, Zonguldak, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taner","family":"Bayraktaroglu","sequence":"additional","affiliation":[{"name":"Endocrinology, Zonguldak B\u00fclent Ecevit University Faculty of Medicine, Zonguldak, Turkey"},{"name":"Obesity and Diabetes Practice and Research Center, Zonguldak B\u00fclent Ecevit University, Zonguldak, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,6,13]]},"reference":[{"key":"ref2","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/s12020-021-02789-9","article-title":"Clinical outcomes of non-diabetic COVID-19 patients with different blood glucose levels: a nationwide Turkish study (TurCoGlycemia)","volume":"73","author":"C Haymana","year":"2021","journal-title":"Endocrine"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1111\/1753-0407.13171","article-title":"Clinical characteristics and outcomes of COVID-19 in patients with type 2 diabetes in Turkey: A nationwide study (TurCoviDia)","volume":"13","author":"A Sonmez","year":"2021","journal-title":"J Diabetes"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1055\/a-1552-4449","article-title":"Clinical characteristics and outcomes of COVID-19 patients with overweight and obesity: Turkish nationwide cohort study (TurCObesity)","volume":"130","author":"I Sahin","year":"2022","journal-title":"Exp Clin Endocrinol Diabetes"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"R229","DOI":"10.1530\/EC-21-0184","article-title":"Early and late endocrine complications of COVID-19","volume":"10","author":"P Kazakou","year":"2021","journal-title":"Endocr Connect"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"e499","DOI":"10.7861\/clinmed.2021-0200","article-title":"Interplay between endocrinology, metabolism and COVID-19 infection","volume":"21","author":"S M Mung","year":"2021","journal-title":"Clin Med (Lond)"},{"key":"ref7","first-page":"100094","article-title":"Manifestations of thyroid disease post COVID-19 illness: report of Hashimoto thyroiditis, Graves\u2019 disease, and subacute thyroiditis","volume":"22","author":"K Feghali","year":"2021","journal-title":"J Clin Transl Endocrinol Case Rep"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"166","DOI":"10.25179\/tjem.2021-82526","article-title":"Disease activity is associated with depression and anxiety in Cushing\u2019s syndrome during COVID-19 pandemic","volume":"25","author":"H Pi\u015fkinpa\u015fa","year":"2021","journal-title":"Turk J Endocrinol Metab"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1530\/EJE-20-0335","article-title":"Thyrotoxicosis in patients with COVID-19: the THYRCOV study","volume":"183","author":"A Lania","year":"2020","journal-title":"Eur J Endocrinol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"344","DOI":"10.25179\/tjem.2021-84279","article-title":"Subacute thyroiditis associated with COVID-19 infection: two case reports","volume":"25","author":"M \u00dcn\u00fcbol","year":"2021","journal-title":"Turk J Endocrinol Metab"},{"key":"ref11","volume-title":"Silent thyroiditis and subacute thyroiditis. 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