{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T10:59:11Z","timestamp":1775473151432,"version":"3.50.1"},"reference-count":31,"publisher":"Georg Thieme Verlag KG","issue":"07","license":[{"start":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T00:00:00Z","timestamp":1657843200000},"content-version":"vor","delay-in-days":14,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background and aims\u2002Artificial intelligence (AI) technology is being evaluated for its potential to improve colonoscopic assessment of inflammatory bowel disease (IBD), particularly with computer-aided image classifiers. This review evaluates the clinical application and diagnostic test accuracy (DTA) of AI algorithms in colonoscopy for IBD.<\/jats:p><jats:p>\n          Methods\u2002A systematic review was performed on studies evaluating AI in colonoscopy of adult patients with IBD. MEDLINE, Embase, Emcare, PsycINFO, CINAHL, Cochrane Library and Clinicaltrials.gov databases were searched on 28th April 2021 for English language articles published between January 1, 2000 and April 28, 2021. Risk of bias and applicability were assessed with the Quality Assessment of Diagnostic Accuracy Studies-2 tool. Diagnostic accuracy was presented as median (interquartile range).<\/jats:p><jats:p>\n          Results\u2002Of 1029 records screened, nine studies with 7813 patients were included for review. AI was used to predict endoscopic and histologic disease activity in ulcerative colitis, and differentiation of Crohn\u2019s disease from Behcet\u2019s disease and intestinal tuberculosis. DTA of AI algorithms ranged between 52\u201391\u200a%. The sensitivity and specificity for AI algorithms predicting endoscopic severity of disease were 78\u200a% (range 72\u201383, interquartile range 5.5) and 91\u200a% (range 86\u201396, interquartile range 5), respectively.<\/jats:p><jats:p>\n          Conclusions\u2002AI has been primarily used to assess disease activity in ulcerative colitis. The diagnostic performance is promising and suggests potential for other clinical application of AI in IBD colonoscopy such as dysplasia detection. However, current evidence is limited by retrospective data and models trained on still images only. Future prospective multicenter studies with full-motion videos are needed to replicate the real-world clinical setting.<\/jats:p>","DOI":"10.1055\/a-1846-0642","type":"journal-article","created":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T22:37:02Z","timestamp":1657924622000},"page":"E1004-E1013","source":"Crossref","is-referenced-by-count":15,"title":["Clinical application and diagnostic accuracy of artificial intelligence in colonoscopy for inflammatory bowel disease: systematic review"],"prefix":"10.1055","volume":"10","author":[{"given":"Linda S.","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, St. Vincent\u2019s Hospital and the University of Melbourne, Fitzroy, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evelyn","family":"Perry","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, St. Vincent\u2019s Hospital and the University of Melbourne, Fitzroy, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonard","family":"Shan","sequence":"additional","affiliation":[{"name":"Department of Surgery, Faculty of Medicine, Dentistry and Health Sciences, the University of Melbourne, Fitzroy, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen","family":"Wilding","sequence":"additional","affiliation":[{"name":"Library Service, St. Vincent\u2019s Hospital Melbourne, Fitzroy, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Connell","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, St. Vincent\u2019s Hospital and the University of Melbourne, Fitzroy, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander J.","family":"Thompson","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, St. Vincent\u2019s Hospital and the University of Melbourne, Fitzroy, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew C. F.","family":"Taylor","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, St. Vincent\u2019s Hospital and the University of Melbourne, Fitzroy, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul V.","family":"Desmond","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, St. Vincent\u2019s Hospital and the University of Melbourne, Fitzroy, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bronte A.","family":"Holt","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, St. Vincent\u2019s Hospital and the University of Melbourne, Fitzroy, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,7,15]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S2468-1253(19)30333-4","article-title":"The global, regional, and national 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