{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T12:05:31Z","timestamp":1746533131306},"reference-count":13,"publisher":"Georg Thieme Verlag KG","issue":"06","license":[{"start":{"date-parts":[[2022,7,4]],"date-time":"2022-07-04T00:00:00Z","timestamp":1656892800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Geburtshilfe Neonatol"],"published-print":{"date-parts":[[2022,12]]},"abstract":"Abstract<\/jats:title>\n Objective To study the factors related to neonatal infection, as well as\n bacterial distribution and drug resistance in neonatal infections, in an\n obstetrics and gynecology hospital in Shanghai.<\/jats:p>\n Methods The bacterial culture and drug resistance monitoring results from\n neonates treated at the hospital from January 2020 to June 2021 were analyzed\n and compared with the data for children and newborns from the national bacterial\n resistance surveillance report.<\/jats:p>\n Results Among the 209 bacterial strains isolated from infected neonates,\n 90 were gram-positive, including the four most common isolates:\n coagulase-negative Staphylococcus, Staphylococcus aureus, Enterococcus, and\n Streptococcus agalactiae. The remaining 119 strains were gram-negative and\n included Klebsiella pneumoniae, Acinetobacter baumannii, and Enterobacter\n aerogenes. The drug sensitivity results showed that the methicillin-resistant\n Staphylococcus aureus isolates were sensitive to linezolid, vancomycin,\n rifampicin, levofloxacin, and gentamicin. All Klebsiella pneumoniaisolates were\n sensitive to amikacin, ertapenem, imipenem, and gentamicin. These two strains\n were resistant to other antibiotics to varying degrees.<\/jats:p>\n Conclusions Understanding the distribution and drug resistance of\n bacterial pathogens is vital for guiding the rational selection of antibiotics\n and reducing neonatal mortality and nosocomial infections.<\/jats:p>","DOI":"10.1055\/a-1850-2475","type":"journal-article","created":{"date-parts":[[2022,7,4]],"date-time":"2022-07-04T23:13:10Z","timestamp":1656976390000},"page":"399-404","source":"Crossref","is-referenced-by-count":4,"title":["Analysis of Factors Related to Neonatal Infection and Monitoring of\n Bacterial Drug Resistance"],"prefix":"10.1055","volume":"226","author":[{"given":"Jingwen","family":"Xu","sequence":"additional","affiliation":[{"name":"Shanghai First Maternity and Infant Hospital, Tongji University School\n of Medicine, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanhong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Shanghai First Maternity and Infant Hospital, Tongji University School\n of Medicine, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Ma","sequence":"additional","affiliation":[{"name":"Shanghai First Maternity and Infant Hospital, Tongji University School\n of Medicine, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renyan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Shanghai First Maternity and Infant Hospital, Tongji University School\n of Medicine, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Wu","sequence":"additional","affiliation":[{"name":"Shanghai First Maternity and Infant Hospital, Tongji University School\n of Medicine, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,7,4]]},"reference":[{"key":"ref1","first-page":"307","article-title":"Analysis of high-risk factors of nosocomial infection in neonatal intensive care\n unit","volume":"192","author":"W Chu","year":"2015","journal-title":"Anhui Medicine"},{"key":"ref2","first-page":"185","article-title":"How to deal with the severe challenges of nosocomial infections of multi-drug\n resistant bacteria","volume":"18","author":"X Meng","year":"2019","journal-title":"Chinese Journal of Infection Control"},{"key":"ref3","first-page":"233","article-title":"Risk factors for nosocomial infection in the neonatal intensive care unit","volume":"16","author":"H Yu","year":"2017","journal-title":"Chinese Journal of Infection Control"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1016\/S0140-6736(14)61698-6","article-title":"Global, regional, and national causes of child mortality in 2000\u201313,\n with projections to inform post-2015 priorities: an updated systematic\n analysis","volume":"385","author":"L Liu","year":"2015","journal-title":"Lancet"},{"key":"ref5","first-page":"837","article-title":"Distribution and drug resistance analysis of Enterobacteriaceae bacteria in a\n hospital","volume":"17","year":"2020","journal-title":"Laboratory Medicine and Clinics"},{"key":"ref7","first-page":"4","article-title":"Distribution and drug resistance analysis of pathogenic bacteria in neonatal\n sepsis","volume":"27","year":"2017","journal-title":"Chinese Journal of Hospital Infection"},{"key":"ref8","first-page":"728","article-title":"The burden of invasive neonatal group B streptococcal (GBS) disease in Thailand\n and the Philippines","volume":"46","author":"M E Villanueva-Uy","year":"2015","journal-title":"Southeast Asian J Trop Med Public 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Maternal and Child Health Care"},{"key":"ref13","first-page":"68","article-title":"Etiology and drug resistance analysis of ventilator-associated pneumonia in\n patients in intensive care unit","volume":"13","author":"K He","year":"2017","journal-title":"Journal of Clinical Pulmonology"},{"key":"ref14","first-page":"1097","article-title":"Study on the correlation between multidrug resistance of ESBLs Klebsiella\n pneumoniae and class I integrons","volume":"14","author":"H Guo","year":"2010","journal-title":"Chinese Journal of Laboratory Diagnosis"}],"container-title":["Zeitschrift f\u00fcr Geburtshilfe und Neonatologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1850-2475.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T00:51:35Z","timestamp":1670547095000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1850-2475"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,4]]},"references-count":13,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2022,12,8]]},"published-print":{"date-parts":[[2022,12]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1850-2475","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0948-2393","1439-1651"],"issn-type":[{"value":"0948-2393","type":"print"},{"value":"1439-1651","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,4]]}}}