{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,12,12]],"date-time":"2023-12-12T05:16:29Z","timestamp":1702358189296},"reference-count":55,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Laryngorhinootologie"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>In j\u00fcngster Zeit wurden in der Therapie der eosinophilen \u00d6sophagitis (EoE) und insbesondere im Bereich der topischen Corticosteroide erhebliche Fortschritte erreicht. Neue EoE-spezifische Darreichungsformen wurden entwickelt und haben in Form der orodispersiblen Budesonid-Tablette zu der ersten in Deutschland und anderen europ\u00e4ischen und au\u00dfereurop\u00e4ischen L\u00e4ndern zugelassenen Therapie der EoE bei Erwachsenen gef\u00fchrt. In den USA steht eine EoE-spezifische orale Budesonid-Suspension kurz vor der Zulassung. Dagegen bleibt die wissenschaftliche Datenlage zur Wirksamkeit von Protonenpumpeninhibtoren weiterhin limitiert. Auch im Bereich der Biologika konnten nach langer Zeit Substanzen identifiziert werden, die erstmals in Phase 2 sehr vielversprechende Ergebnisse gezeigt haben und sich derzeit in klinischen Pr\u00fcfungen der Phase 3 befinden. In diesem Artikel sollen die aktuellen Fortschritte und Perspektiven in der Therapie der EoE dargestellt und diskutiert werden.<\/jats:p>","DOI":"10.1055\/a-1861-7152","type":"journal-article","created":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T22:30:32Z","timestamp":1683239432000},"page":"339-348","source":"Crossref","is-referenced-by-count":0,"title":["Therapie der eosinophilen \u00d6sophagitis - Fortschritte und Perspektiven"],"prefix":"10.1055","volume":"102","author":[{"given":"Stephan","family":"Miehlke","sequence":"additional","affiliation":[{"name":"Magen-Darm-Zentrum, Facharztzentrum Eppendorf, Hamburg, Germany"},{"name":"Universit\u00e4tsklinikum Hamburg-Eppendorf, Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrike von","family":"Arnim","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hepatology and Infectious diseases, Universit\u00e4tsklinikum Magdeburg A\u00f6R, Magdeburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Schlag","sequence":"additional","affiliation":[{"name":"Second medical department, Klinikum rechts der Isar der Technischen Universit\u00e4t M\u00fcnchen, Munchen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joachim","family":"Labenz","sequence":"additional","affiliation":[{"name":"Medizinische Klinik, Ev. 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