{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:33:52Z","timestamp":1740126832359,"version":"3.37.3"},"reference-count":23,"publisher":"Georg Thieme Verlag KG","issue":"S 01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>\n            Objectives\u2003This study aimed to compare the effects of volume guarantee (VG) combined with assist\/control (AC) ventilation to AC alone on hypocarbia episodes and extubation success in infants born at or near term.<\/jats:p><jats:p>\n            Methods\u2003In this prospective cohort study, infants &gt;34 weeks of gestation at birth, who were born in our hospital supported by synchronized, time-cycled, pressure limited, assist\/control ventilation (AC) or assist-controlled VG mechanical ventilation (AC\u2009+\u2009VG) were included. After admission, infants received either AC or VG\u2009+\u2009AC using by Leoni Plus ventilator. The ventilation mode was left to the clinician. In the AC group, peak airway pressure was set clinically. In the VG\u2009+\u2009AC group, desired tidal volume was set at 5\u2009mL\/kg, with the ventilator adjusting peak inspiratory pressure to deliver this volume. The study was completed once the patient extubated.<\/jats:p><jats:p>\n            Results\u2003There were 35 patients in each group. Incidence of hypocarbia was lower in the VG\u2009+\u2009AC compared with AC (%17.1 and 22.8%, respectively) but statistically not significant. Out-of-range partial pressure of carbon dioxide (PCO2) levels were lower in the VG\u2009+\u2009AC group and it reached borderline statistical significance (p\u2009=\u20090.06). The median extubation time was 70 (42\u2013110) hours in the VG\u2009+\u2009AC group, 89.5 (48.5\u2013115.5) hours in the AC group, and it did not differ between groups (p\u2009=\u20090.47).<\/jats:p><jats:p>\n            Conclusion\u2003We found combining AC and VG ventilation compared with AC ventilation alone yielded similar hypocarbia episodes and extubation time for infants of &gt;34 gestational weeks with borderline significance lower out-of-range PCO2 incidence.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/a-1862-0078","type":"journal-article","created":{"date-parts":[[2022,5,26]],"date-time":"2022-05-26T01:47:42Z","timestamp":1653529662000},"page":"e174-e179","source":"Crossref","is-referenced-by-count":0,"special_numbering":"S","title":["Comparison of Assist\/Control Ventilation with and without Volume Guarantee in Term or Near-Term Infants"],"prefix":"10.1055","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5720-7104","authenticated-orcid":false,"given":"Handan","family":"Bezirganoglu","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, University of Health Sciences, Ankara City Hospital, Ankara, T\u00fcrkiye"},{"name":"Division of Neonatology, Trabzon Kanuni Training and Research Hospital, Trabzon, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nilufer","family":"Okur","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, University of Health Sciences, Ankara City Hospital, Ankara, T\u00fcrkiye"},{"name":"Division of Neonatology, Diyarbakir Gazi Yasargil Training and Research Hospital, Diyarbakir, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8937-4671","authenticated-orcid":false,"given":"Mehmet","family":"Buyuktiryaki","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, University of Health Sciences, Ankara City Hospital, Ankara, T\u00fcrkiye"},{"name":"Division of Neonatology, Department of Pediatrics, \u0130stanbul Medipol University Medical School, \u0130stanbul, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serife S.","family":"Oguz","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, University of Health Sciences, Ankara City Hospital, Ankara, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evrim A.","family":"Dizdar","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, University of Health Sciences, Ankara City 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