{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T10:47:24Z","timestamp":1778064444260,"version":"3.51.4"},"reference-count":30,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg B Skull Base"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Introduction\u2003Transnasal access to the anterior skull base provides a minimally invasive approach for sellar and parasellar masses compared with its open counterparts. The unique microbiome of the sinonasal mucosa provides distinct challenges not encountered with other cranial approaches. The use of antibiotics in these cases has not been standardized, and data remain scarce regarding infectious outcomes.<\/jats:p><jats:p>\n          Methods\u2003We conducted a multicenter retrospective analysis of shared quality data points for the endoscopic endonasal approach (EEA) for pituitary adenomas, along with other sellar and parasellar region masses that were included by participating institutions. Patient and operative characteristics, perioperative and postoperative antibiotic regimens and their durations, intraoperative and postoperative cerebrospinal fluid leak, and onset of postoperative meningitis and sinusitis were compared.<\/jats:p><jats:p>\n          Results\u2003Fifteen institutions participated and provided 6 consecutive months' worth of case data. Five hundred ninety-three cases were included in the study, of which 564 were pituitary adenomectomies. The incidences of postoperative meningitis and sinusitis were low (0.67 and 2.87% for all pathologies, respectively; 0.35% meningitis for pituitary adenomas) and did not correlate with any specific antibiotic regimen. Immunocompromised status posed an increased odds of meningitis in pituitary adenomectomies (28.6, 95% confidence interval [1.72\u2013474.4]).<\/jats:p><jats:p>\n          Conclusions\u2003The results show no clear benefit to postoperative antimicrobial use in EEA, with further larger studies needed.<\/jats:p>","DOI":"10.1055\/a-1865-3202","type":"journal-article","created":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T06:27:51Z","timestamp":1654064871000},"page":"579-588","source":"Crossref","is-referenced-by-count":4,"title":["Retrospective Review of Surgical Site Infections after Endoscopic Endonasal Sellar and Parasellar Surgery: Multicenter Quality Data from the North American Skull Base Society"],"prefix":"10.1055","volume":"83","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2127-8701","authenticated-orcid":false,"given":"Sara","family":"Saleh","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Michigan, Ann Arbor, Michigan, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen E.","family":"Sullivan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Michigan, Ann Arbor, Michigan, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"Bellile","sequence":"additional","affiliation":[{"name":"Cancer Data Science, Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Roxbury","sequence":"additional","affiliation":[{"name":"Section of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of Chicago, Chicago, Illinois, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paramita","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Chicago, Chicago, Illinois, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralph Abi","family":"Hachem","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery and Communication Sciences, Duke University, Durham, North Carolina, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feras","family":"Ackall","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery and Communication Sciences, Duke University, Durham, North Carolina, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Gazi University Faculty of Medicine, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5733-7542","authenticated-orcid":false,"given":"Emrah","family":"Celtikci","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Gazi University Faculty of Medicine, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muammer Melih","family":"Sahin","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, Gazi University Faculty of Medicine, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Glen","family":"D'souza","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Thomas Jefferson University, Philadelphia, Pennsylvania, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James J.","family":"Evans","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Thomas Jefferson University, Philadelphia, Pennsylvania, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gurston","family":"Nyquist","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Thomas Jefferson University, Philadelphia, Pennsylvania, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adham","family":"Khalafallah","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Miami\/Jackson Health System, Miami, Florida, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5403-8237","authenticated-orcid":false,"given":"Debraj","family":"Mukherjee","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Johns Hopkins University, Baltimore, Maryland, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1296-2648","authenticated-orcid":false,"given":"Nicholas R.","family":"Rowan","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Johns Hopkins University, Baltimore, Maryland, United 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Van","family":"Gompel","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery and Otorhinolaryngology, Mayo Clinic, Rochester, Minnesota, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael K.","family":"Ghiam","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, University of Miami, Miami, Florida, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corinna G.","family":"Levine","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, University of Miami, Miami, Florida, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melvin","family":"Field","sequence":"additional","affiliation":[{"name":"Orlando Neurosurgery, Orlando, Florida, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nithin","family":"Adappa","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, University of Pennsylvania, Philadelphia, Pennsylvania, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tran B.","family":"Locke","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Rassekh","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, University of Pennsylvania, Philadelphia, Pennsylvania, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Auddie M.","family":"Sweis","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2013Head and Neck Surgery, Northshore University Health System, University of Chicago Pritzker School of Medicine, Chicago, Illinois, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7783-1097","authenticated-orcid":false,"given":"Neerav","family":"Goyal","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, Penn State Milton S. 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Hershey Medical Center, Hershey, Pennsylvania, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul A.","family":"Gardner","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carl H.","family":"Snyderman","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric W.","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurence Johann","family":"Glancz","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Queen's Medical Centre, Nottingham, United Kingdom"},{"name":"Manchester Skullbase Unit, Salford Royal Hospital, Manchester, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ananyo","family":"Bagchi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Queen's Medical Centre, Nottingham, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graham","family":"Dow","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Queen's Medical Centre, Nottingham, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iain","family":"Robertson","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Queen's Medical Centre, Nottingham, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjeet V.","family":"Rangarajan","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head-Neck Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"II","given":"L. Madison","family":"Michael","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Tennessee Health Science Center, Memphis, Tennessee, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin L.","family":"McKean","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, University of Michigan, Ann Arbor, Michigan, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,8,25]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/j.wneu.2019.03.048","article-title":"Endoscopic endonasal transsphenoidal surgery: History and evolution","volume":"127","author":"L M Cavallo","year":"2019","journal-title":"World Neurosurg"},{"issue":"03","key":"ref2","doi-asserted-by":"crossref","first-page":"570","DOI":"10.3171\/jns.2005.103.3.0570","article-title":"Cushing's first case of transsphenoidal surgery: the 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