{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T11:29:15Z","timestamp":1790422155659,"version":"4.1.0"},"reference-count":20,"publisher":"Georg Thieme Verlag KG","issue":"10","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Geburtshilfe Frauenheilkd"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Introduction Endometrial cancer is the most common malignant tumor of the female genital organs. In Germany, treatment is provided in both cancer centers certified by the German Cancer Society (Deutsche Krebsgesellschaft, DKG) and in non-certified hospitals. This study investigated whether treatment in DKG-certified centers leads to improved overall survival of patients with endometrial cancer.<\/jats:p>\n                  <jats:p>Materials and Methods Data from 11 legally independent German statutory health insurance (SHI) funds of the AOK were analyzed as well as data from four clinical cancer registries (CCR), resulting in inclusion of 30\u200a102 AOK patients and 8190 registry patients with a diagnosis (incidental cases) of ICD-10-GM code C54 (malignant neoplasm of corpus uteri). For comparative survival analyses, multivariable Cox regressions and Kaplan\u2013Meier analyses were used.<\/jats:p>\n                  <jats:p>Results The Kaplan\u2013Meier estimator for 5-year overall survival was 66.7% for patients from certified centers and 65.0% for patients from non-certified hospitals (using SHI data; CCR data: 63.4% vs. 60.7%). Cox regression adjusted for relevant confounders showed a hazard ratio (HR) of 0.93 (SHI data; 95%\u00a0CI 0.86\u200a\u2013\u200a1.00; p\u2009=\u20090.050) and 0.935 (CCR data; 95% CI 0.827\u200a\u2013\u200a1.057; p\u2009=\u20090.281) for all-cause mortality. In a subgroup analysis (CCR), patients with International Union against Cancer Control (UICC) stage I had a significant survival benefit if treated in a certified center (HR 0.783; 95% CI 0.620\u200a\u2013\u200a0.987; p\u2009=\u20090.038).<\/jats:p>\n                  <jats:p>Conclusion The study presented herein shows that patients with endometrial cancer treated in a certified cancer center tend to have better survival rates. This should be considered when selecting the treating hospital.<\/jats:p>","DOI":"10.1055\/a-1869-2060","type":"journal-article","created":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T18:48:12Z","timestamp":1727808492000},"page":"979-988","source":"Crossref","is-referenced-by-count":8,"title":["Endometrial Cancer \u2013 Long-Term Survival in Certified Cancer Centers and Non-Certified Hospitals"],"prefix":"10.1055","volume":"84","author":[{"given":"Judith","family":"Hansinger","sequence":"additional","affiliation":[{"name":"Tumorzentrum Regensburg, Zentrum f\u00fcr Qualit\u00e4tssicherung und Versorgungsforschung der Universit\u00e4t Regensburg, Regensburg, Germany"},{"name":"Bavarian Cancer Research Center (BZKF), Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinzenz","family":"V\u00f6lkel","sequence":"additional","affiliation":[{"name":"Tumorzentrum Regensburg, Zentrum f\u00fcr Qualit\u00e4tssicherung und Versorgungsforschung der Universit\u00e4t Regensburg, Regensburg, Germany"},{"name":"Bavarian Cancer Research Center (BZKF), Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Gerken","sequence":"additional","affiliation":[{"name":"Tumorzentrum Regensburg, Zentrum f\u00fcr Qualit\u00e4tssicherung und Versorgungsforschung der Universit\u00e4t Regensburg, Regensburg, Germany"},{"name":"Bayerisches Krebsregister, Regionalzentrum Regensburg, Bayerisches Landesamt f\u00fcr Gesundheit und Lebensmittelsicherheit, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olaf","family":"Schoffer","sequence":"additional","affiliation":[{"name":"Zentrum f\u00fcr Evidenzbasierte Gesundheitsversorgung, Universit\u00e4tsklinikum und Medizinische Fakult\u00e4t Carl Gustav Carus an der Technischen Universit\u00e4t Dresden, Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pauline","family":"Wimberger","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Frauenheilkunde und Geburtshilfe, Universit\u00e4tsklinikum Carl Gustav Carus an der Technischen Universit\u00e4t Dresden, Dresden, Germany"},{"name":"National Center of Tumor Diseases (NCT) Dresden, Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronika","family":"Bierbaum","sequence":"additional","affiliation":[{"name":"Zentrum f\u00fcr Evidenzbasierte Gesundheitsversorgung, Universit\u00e4tsklinikum und Medizinische Fakult\u00e4t Carl Gustav Carus an der Technischen Universit\u00e4t Dresden, Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Bobeth","sequence":"additional","affiliation":[{"name":"Zentrum f\u00fcr Evidenzbasierte Gesundheitsversorgung, Universit\u00e4tsklinikum und Medizinische Fakult\u00e4t Carl Gustav Carus an der Technischen Universit\u00e4t Dresden, Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"R\u00f6\u00dfler","sequence":"additional","affiliation":[{"name":"Zentrum f\u00fcr Evidenzbasierte Gesundheitsversorgung, Universit\u00e4tsklinikum und Medizinische Fakult\u00e4t Carl Gustav Carus an der Technischen Universit\u00e4t Dresden, Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrik","family":"Dr\u00f6ge","sequence":"additional","affiliation":[{"name":"AOK Research Institute (WIdO), Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Ruhnke","sequence":"additional","affiliation":[{"name":"AOK Research Institute (WIdO), Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"G\u00fcnster","sequence":"additional","affiliation":[{"name":"AOK Research Institute (WIdO), Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kees Kleihues-van","family":"Tol","sequence":"additional","affiliation":[{"name":"Arbeitsgemeinschaft Deutscher Tumorzentren e.\u200aV., Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresa","family":"Link","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Frauenheilkunde und Geburtshilfe, Universit\u00e4tsklinikum Carl Gustav Carus an der Technischen Universit\u00e4t Dresden, Dresden, Germany"},{"name":"National Center of Tumor Diseases (NCT) Dresden, Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Kast","sequence":"additional","affiliation":[{"name":"Zentrum Famili\u00e4rer Brust- und Eierstockkrebs und Centrum f\u00fcr Integrierte Onkologie, Universit\u00e4t zu K\u00f6ln, K\u00f6ln, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Papathemelis","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Frauenheilkunde und Geburtshilfe, Klinikum St. Marien Amberg, Amberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olaf","family":"Ortmann","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Frauenheilkunde und Geburtshilfe, Lehrstuhl der Universit\u00e4t Regensburg, Caritas-Krankenhaus St.Josef, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jochen","family":"Schmitt","sequence":"additional","affiliation":[{"name":"Zentrum f\u00fcr Evidenzbasierte Gesundheitsversorgung, Universit\u00e4tsklinikum und Medizinische Fakult\u00e4t Carl Gustav Carus an der Technischen Universit\u00e4t Dresden, Dresden, 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