{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T08:42:14Z","timestamp":1762072934830,"version":"build-2065373602"},"reference-count":18,"publisher":"Georg Thieme Verlag KG","issue":"22","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dtsch Med Wochenschr"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Was ist neu?<\/jats:title><jats:p>\n          Morbidit\u00e4t und Mortalit\u00e4t.\u2002Patienten mit peripherer arterieller Verschlusskrankheit (pAVK) und Diabetes mellitus stellen eine vulnerable Patientengruppe dar. Sie weisen im Vergleich zu pAVK-Patienten ohne Diabetes eine erh\u00f6hte Morbidit\u00e4t und eine gesteigerte Mortalit\u00e4t auf.<\/jats:p><jats:p>\n          Diabetes mellitus \u2013 ein relevanter Risikofaktor f\u00fcr Amputationen.\u2002Das Vorliegen eines Diabetes mellitus stellt bei Menschen mit einer pAVK ein erhebliches Risiko f\u00fcr eine Amputation dar. Die Inzidenz von Major-Amputationen bei Diabetikern ist nach einer aktuellen Studie 10-mal und von Minor-Amputationen 15-mal h\u00f6her als bei Nichtdiabetikern. Eine Amputation bei Menschen mit Diabetes mellitus hat zudem einen erheblichen Einfluss auf die Morbidit\u00e4t und Mortalit\u00e4t.<\/jats:p><jats:p>\n          Optimierung der Patientenversorgung notwendig.\u2002Trotz gro\u00dfer Anstrengungen im Gesundheitssystem repr\u00e4sentiert der Diabetes mellitus weiterhin einen bedeutenden Risikofaktor, auch bei Menschen mit pAVK. Unabh\u00e4ngig vom Vorliegen eines Diabetes mellitus wird eine pAVK wiederum bei betroffenen Menschen oftmals nicht erkannt oder nicht ad\u00e4quat therapiert. Nur wenige Menschen mit pAVK werden gef\u00e4\u00dfmedizinisch betreut. Zur Reduktion von Morbidit\u00e4t und Mortalit\u00e4t sind Pr\u00e4vention, fr\u00fchzeitige Detektion sowie eine optimale Therapie von pAVK und Diabetes mellitus allerdings essenziell.<\/jats:p>","DOI":"10.1055\/a-1902-6778","type":"journal-article","created":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T23:40:51Z","timestamp":1667346051000},"page":"1433-1437","source":"Crossref","is-referenced-by-count":2,"title":["Periphere arterielle Verschlusskrankheit bei Diabetes mellitus"],"prefix":"10.1055","volume":"147","author":[{"given":"Volker H.","family":"Schmitt","sequence":"additional","affiliation":[{"name":"Zentrum f\u00fcr Kardiologie, Kardiologie III \u2013 Angiologie, Universit\u00e4tsmedizin der Johannes Gutenberg-Universit\u00e4t Mainz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karsten","family":"Keller","sequence":"additional","affiliation":[{"name":"Zentrum f\u00fcr Kardiologie, Kardiologie I, Universit\u00e4tsmedizin der Johannes Gutenberg-Universit\u00e4t Mainz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Espinola-Klein","sequence":"additional","affiliation":[{"name":"Zentrum f\u00fcr Kardiologie, Kardiologie III \u2013 Angiologie, Universit\u00e4tsmedizin der Johannes Gutenberg-Universit\u00e4t Mainz"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,11,1]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1093\/eurheartj\/ehx095","article-title":"2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS): Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteriesEndorsed by: the European Stroke Organization (ESO)The Task Force for the Diagnosis and Treatment of Peripheral Arterial Diseases of the 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