{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T08:36:50Z","timestamp":1784795810980,"version":"3.55.0"},"reference-count":26,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg K Kleintiere Heimtiere"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Gegenstand und Ziel\u2002W\u00e4hrend viele zuchtbedingte Malformationen des Sch\u00e4dels bei brachyzephalen Hunden bereits wohlbekannt sind, vor allem jene, die zu dramatischen Atemproblemen f\u00fchren, sind Ver\u00e4nderungen des Mittelohrs oft klinisch inapparent und ein Zufallsbefund bei CT-Untersuchungen. Ziel dieser Arbeit war die Untersuchung der Pr\u00e4valenz und Charakterisierung von Paukenh\u00f6hlenerg\u00fcssen bei brachyzephalen Hunden, die zur chirurgischen Therapie des Brachyzephalen Syndroms vorgestellt wurden.<\/jats:p><jats:p>\n          Material und Methoden\u2002Brachyzephale Hunde, bei denen ein Paukenh\u00f6hlenerguss als Zufallsbefund in einer Computertomografie festgestellt wurde, wurden prospektiv in die Studie eingeschlossen. Es wurde eine endoskopische Tympanozentese durchgef\u00fchrt, im Anschluss wurde das gewonnene Material makroskopisch beschrieben, mikroskopisch untersucht sowie eine bakteriologische Untersuchung eingeleitet.<\/jats:p><jats:p>\n          Ergebnisse\u2002Im Studienzeitraum wurden 170\u2005Hunde zur Behandlung eines Brachyzephalen Syndroms in der Klinik f\u00fcr Kleintiere vorgestellt. Die Pr\u00e4valenz lag bei 55\/170\u2005Tieren (32\u2009%), 86\u2005Ohren waren betroffen. Die einzigen Rassen, bei denen ein Paukenh\u00f6hlenerguss auftrat, waren Franz\u00f6sische Bulldoggen (FB) und M\u00f6pse. Die Pr\u00e4valenz lag bei 35\/66 (53\u2009%) aller FB und bei 20\/79 (25\u2009%) aller M\u00f6pse. Eine Tympanozentese konnte bei 80\u2005Ohren erfolgreich durchgef\u00fchrt werden. In den meisten F\u00e4llen war das gewonnene Sekret muk\u00f6s oder ser\u00f6s mit einer honigartigen Farbe. In 76\u2005Ohren konnte gen\u00fcgend Material f\u00fcr eine BU gewonnen werden, die in 34\u2005F\u00e4llen (45\u2009%) positiv ausfiel. Von 73\u2005Proben konnte eine zytologische Untersuchung durchgef\u00fchrt werden. In allen Proben fanden sich Entz\u00fcndungszellen, in 23 (31,5\u2009%) mit einer hohen Konzentration.<\/jats:p><jats:p>\n          Schlussfolgerungen und klinische Relevanz Brachyzephale Hunde haben eine hohe Pr\u00e4valenz von Paukenh\u00f6hlenerg\u00fcssen. Die zytologischen Befunde unterscheiden sich dabei stark von den in der Regel zellfreien Sekreten bei Cavalier King Charles Spaniels, die unter den klinischen Symptomen einer Prim\u00e4r Sekretorischen Otitis Media leiden. Eine Studie, die das Sekret von Hunden ohne klinische Symptome und Hunden mit vestibul\u00e4ren St\u00f6rungen vergleichend analysiert, erscheint indiziert, um die klinische Signifikanz von Paukenh\u00f6hlenerg\u00fcssen weiter bestimmen zu k\u00f6nnen.<\/jats:p>","DOI":"10.1055\/a-1913-7216","type":"journal-article","created":{"date-parts":[[2022,9,14]],"date-time":"2022-09-14T00:11:25Z","timestamp":1663114285000},"page":"329-336","source":"Crossref","is-referenced-by-count":9,"title":["Prevalence and characterization of middle ear effusion in 55\u2005brachycephalic dogs"],"prefix":"10.1055","volume":"50","author":[{"given":"Riccarda","family":"Schuenemann","sequence":"additional","affiliation":[{"name":"Department for Small Animals, Faculty of Veterinary Medicine, University of Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Kamradt","sequence":"additional","affiliation":[{"name":"Department for Small Animals, Faculty of Veterinary Medicine, University of Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrin","family":"Truar","sequence":"additional","affiliation":[{"name":"Department for Small Animals, Faculty of Veterinary Medicine, University of Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerhard","family":"Oechtering","sequence":"additional","affiliation":[{"name":"Department for Small Animals, Faculty of Veterinary Medicine, University of Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,9,13]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1046\/j.1365-2273.2000.00350.x","article-title":"The aetiology of otitis media with effusion: a review","volume":"25","author":"H Kubba","year":"2000","journal-title":"Clin Otolaryngol Allied Sci"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1111\/jsap.12397","article-title":"Video-otoscopy-guided tympanostomy tube placement for treatment of middle ear effusion","volume":"56","author":"V Guerin","year":"2015","journal-title":"J Small Anim Pract"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1111\/j.1748-5827.2003.tb00151.x","article-title":"Primary secretory otitis media in the Cavalier King Charles spaniel: a review of 61 cases","volume":"44","author":"W Stern-Bertholtz","year":"2003","journal-title":"J Small Anim Pract"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1136\/vr.153.9.260","article-title":"Neurological signs and results of magnetic resonance imaging in 40 cavalier King Charles spaniels with Chiari type 1-like malformations","volume":"153","author":"D Lu","year":"2003","journal-title":"Vet Rec"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1136\/vr.b4886","article-title":"Relationship between pharyngeal conformation and otitis media with effusion in Cavalier King Charles spaniels","volume":"167","author":"GM Hayes","year":"2010","journal-title":"Vet Rec"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1111\/vru.12529","article-title":"Computed tomographic morphometry of tympanic bulla shape and position in brachycephalic and mesaticephalic dog breeds","volume":"58","author":"B Mielke","year":"2017","journal-title":"Vet Radiol Ultrasound"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/j.ijporl.2008.03.027","article-title":"Craniofacial morphology and otitis media with effusion in children","volume":"72","author":"R Di Francesco","year":"2008","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"ref8","first-page":"533","volume-title":"Neuro-otology: problem of dizziness, balance and hearing","author":"R Davies","year":"2009"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/j.1740-8261.2004.04025.x","article-title":"Material in the middle ear of dogs having magnetic resonance imaging for investigation of neurologic signs","volume":"45","author":"MC Owen","year":"2004","journal-title":"Vet Radiol Ultrasound"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.tvjl.2010.09.015","article-title":"Middle ear effusions in dogs: an incidental finding?","volume":"188","author":"HA Volk","year":"2011","journal-title":"Vet J"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/S0030-6665(20)30365-0","article-title":"Eustachian tube dysfunction","volume":"29","author":"EM Monsell","year":"1996","journal-title":"Otolaryngol Clin North Am"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1288\/00005537-197502000-00015","article-title":"Density of goblet cells in chronic secretory otitis media: findings in a biopsy material","volume":"85","author":"M Tos","year":"1975","journal-title":"Laryngoscope"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/j.1748-5827.1985.tb02088.x","article-title":"Experimental induction of secretory and purulent otitis media by the surgical obstruction of the eustachian tube in dogs","volume":"26","author":"M Tojo","year":"1985","journal-title":"J Small Anim Pract"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1111\/j.1751-0813.2008.00254.x","article-title":"The method of application and short term results of tympanostomy tubes for the treatment of primary secretory otitis media in three Cavalier King Charles Spaniel dogs","volume":"86","author":"GS Corfield","year":"2008","journal-title":"Aust Vet J"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1136\/vr.101337","article-title":"Progression of otitis media with effusion in the Cavalier King Charles spaniel","volume":"172","author":"SJ McGuinness","year":"2013","journal-title":"Vet Rec"},{"key":"ref16","first-page":"499","article-title":"Role of nasopharyngeal reflux in the etiology of otitis media with effusion","volume":"40","author":"E Aydin","year":"2011","journal-title":"J Otolaryngol Head Neck Surg"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1111\/j.1748-5827.2005.tb00320.x","article-title":"Prevalence of gastrointestinal tract lesions in 73 brachycephalic dogs with upper respiratory syndrome","volume":"46","author":"CM Poncet","year":"2005","journal-title":"J Small Anim Pract"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1111\/jsap.12914","article-title":"Relationship between brachycephalic airway syndrome and gastrointestinal signs in three breeds of dog","volume":"59","author":"BM Kaye","year":"2015","journal-title":"J Small Anim Pract"},{"issue":"02","key":"ref21","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1111\/vde.12724","article-title":"Bacteriology and cytology of otic exudates in 41 cavalier King Charles spaniels with primary secretory otitis media","volume":"30","author":"LK Cole","year":"2019","journal-title":"Vet Dermatol"},{"issue":"04","key":"ref22","doi-asserted-by":"publisher","first-page":"1454","DOI":"10.1111\/jvim.15792","article-title":"Cytological and microbiological characteristics of middle ear effusions in brachycephalic dogs","volume":"34","author":"E Milne","year":"2020","journal-title":"J Vet Intern Med"},{"key":"ref23","first-page":"218","volume-title":"Chronic Otitis Media and Cholesteatoma","author":"RA Chole","year":"2009"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"261","DOI":"10.5326\/JAAHA-MS-5760","article-title":"Cholesteatoma after lateral bulla osteotomy in two brachycephalic dogs","volume":"48","author":"RM Schuenemann","year":"2012","journal-title":"J Am Anim Hosp Assoc"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1111\/j.1748-5827.1969.tb04013.x","article-title":"Canine ear disease","volume":"10","author":"G Fraser","year":"1970","journal-title":"Journal Of Small Animal Practice"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.cvsm.2003.10.007","article-title":"Diagnosis and treatment of otitis media in dogs and cats","volume":"34","author":"LN Gotthelf","year":"2004","journal-title":"Vet Clin North Am Small Anim Pract"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1111\/j.1748-5827.1984.tb03390.x","article-title":"The aerobic bacterial flora of the middle and external ears in normal dogs","volume":"25","author":"H Matsuda","year":"1984","journal-title":"Journal Of Small Animal Practice"},{"key":"ref28","first-page":"CD009163","article-title":"Antibiotics for otitis media with effusion in children","volume":"9","author":"A van Zon","year":"2012","journal-title":"Cochrane Database Syst Rev"}],"container-title":["Tier\u00e4rztliche Praxis Ausgabe K: Kleintiere \/ Heimtiere"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1913-7216.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,3]],"date-time":"2022-11-03T00:30:26Z","timestamp":1667435426000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1913-7216"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,13]]},"references-count":26,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2022,11,2]]},"published-print":{"date-parts":[[2022,10]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1913-7216","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1434-1239","2567-5842"],"issn-type":[{"value":"1434-1239","type":"print"},{"value":"2567-5842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,13]]}}}