{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T10:09:19Z","timestamp":1746785359225,"version":"3.37.3"},"reference-count":37,"publisher":"Georg Thieme Verlag KG","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Monbl Augenheilkd"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Hintergrund Prim\u00e4re Tumoren der Papille stellen den behandelnden Augenarzt oft vor Herausforderungen. Sie weisen sehr unterschiedliche Erscheinungsbilder auf und viele prim\u00e4re\n\t\t\t\t\tPapillentumoren sind mit Syndromerkrankungen (vor allem Phakomatosen) assoziiert. Wegen der Seltenheit fallen Einordnung und Einsch\u00e4tzung oft schwer.<\/jats:p><jats:p>\n          Material und Methoden Es erfolgte eine systematische Suche in den elektronischen Patientenakten (Zeitraum 01.01.2015\u200a\u2013\u200a01.06.2022) der Klinik f\u00fcr Augenheilkunde des\n\t\t\t\t\tUniversit\u00e4tsklinikums M\u00fcnster nach Patienten mit prim\u00e4ren Papillentumoren. F\u00fcr jede Tumorentit\u00e4t wurden exemplarisch F\u00e4lle ausgesucht, die hier ausf\u00fchrlicher vorgestellt werden. Die\n\t\t\t\t\tKriterien zur exemplarischen Auswahl der F\u00e4lle waren eine eindeutige Diagnose, das Vorliegen geeigneten Bildmaterials und Folgeuntersuchungen in unserer Klinik.<\/jats:p><jats:p>\n          Ergebnisse Die Suche ergab 7 F\u00e4lle mit 3 verschiedenen prim\u00e4ren Tumorentit\u00e4ten im Bereich der Papille (kapill\u00e4res H\u00e4mangioblastom, astrozyt\u00e4res Hamartom und Melanozytom). Es wurden\n\t\t\t\t\texemplarisch 4 Patienten herausgesucht, die hier vorgestellt werden: 2 F\u00e4lle zum kapill\u00e4ren H\u00e4mangioblastom (einmal isoliert und zum anderen im Rahmen eines Von-Hippel-Lindau-Syndroms) sowie\n\t\t\t\t\tjeweils ein Fall zum astrozyt\u00e4ren Hamartom und zum Melanozytom. Wir skizzieren die weitere Diagnostik und den Krankheitsverlauf und geben einen \u00dcberblick \u00fcber die wesentlichen Merkmale der\n\t\t\t\t\tjeweils zugrunde liegenden Tumoren.<\/jats:p><jats:p>\n          Schlussfolgerung Die Kenntnis der unterschiedlichen prim\u00e4ren Tumoren im Bereich der Papille ist f\u00fcr eine korrekte Diagnosefindung notwendig. So gelingt die Abgrenzung zu malignen\n\t\t\t\t\tProzessen und Papillenanomalien. In vielen F\u00e4llen ist eine interdisziplin\u00e4re weitergehende Diagnostik notwendig. Die multimodale Bildgebung ist hilfreich und eine Anbindung an ein Zentrum\n\t\t\t\t\tsinnvoll.<\/jats:p>","DOI":"10.1055\/a-1927-4111","type":"journal-article","created":{"date-parts":[[2022,8,18]],"date-time":"2022-08-18T22:47:36Z","timestamp":1660862856000},"page":"1325-1336","source":"Crossref","is-referenced-by-count":3,"title":["Prim\u00e4re Papillentumoren \u2013 Fallserie und Literatur\u00fcberblick"],"prefix":"10.1055","volume":"239","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6571-4117","authenticated-orcid":false,"given":"Martin Dominik","family":"Leclaire","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Augenheilkunde, Universit\u00e4tsklinikum M\u00fcnster, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannah","family":"Schatten","sequence":"additional","affiliation":[{"name":"Zentrum f\u00fcr Augenheilkunde, Universit\u00e4tsklinikum K\u00f6ln, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5510-3857","authenticated-orcid":false,"given":"Julia","family":"Biermann","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Augenheilkunde, Universit\u00e4tsklinikum M\u00fcnster, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,11,21]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1055\/s-0043-108489","article-title":"Die randunscharfe Papille: eine diagnostische Herausforderung","volume":"234","author":"J Biermann","year":"2017","journal-title":"Klin Monbl Augenheilkd"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/0039-6257(85)90149-3","article-title":"Tumors of the optic nerve head","volume":"29","author":"G C Brown","year":"1985","journal-title":"Surv Ophthalmol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1034\/j.1600-0420.2000.078002156.x","article-title":"Tumors and pseudotumors of the optic disc","volume":"78","author":"J A Shields","year":"2000","journal-title":"Acta Ophthalmol Scand"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1034\/j.1600-0420.2001.079001083.x","article-title":"Solitary peripapillary hemangioblastoma. 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