{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T18:30:16Z","timestamp":1792693816109,"version":"4.5.0"},"reference-count":30,"publisher":"Georg Thieme Verlag KG","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Monbl Augenheilkd"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Hintergrund Es soll die Sicherheit im Stra\u00dfenverkehr beim Tragen von Brillengl\u00e4sern mit DIMS-Technologie (DIMS: Defocus Incorporated Multiple Segments) in der Kombination mit Atropin\n\t\t\t\t\tevaluiert werden.<\/jats:p><jats:p>\n          Patienten und Methoden An 12 jungen Erwachsenen (Alter: 24\u200a\u2013\u200a45; 30,1\u2009\u00b1\u20095,7 Jahre) wurde der Fernvisus und die Kontrastempfindlichkeit (KE), sowie Blendempfindlichkeit bei Versorgung\n\t\t\t\t\tmit DIMS-Brillengl\u00e4sern allein und in der Kombination mit 0,01% Atropin untersucht.<\/jats:p><jats:p>\n          Ergebnisse Durch Atropineinwirkung vermindert sich der Fernvisus beim Blick durch den zentralen Bereich des DIMS-Brillenglases nicht; bei Blendung und unter Atropin kommt es zu einem\n\t\t\t\t\tVisusabfall um 0,10 logMAR. Beim erzwungenen Blick durch den DIMS-Bereich vermindert sich der Fernvisus durch Atropineinwirkung ohne Blendung um 0,09 logMAR; bei Blendung ist durch Atropin\n\t\t\t\t\tkein weiterer Visusabfall zu beobachten. Die Kontrastempfindlichkeit mit DIMS-Gl\u00e4sern wird durch Atropineinwirkung nicht relevant ver\u00e4ndert. Hinsichtlich der Blendempfindlichkeit findet sich\n\t\t\t\t\tbei DIMS-Gl\u00e4sern keine f\u00fcr das Sehen und die Sicherheit im Stra\u00dfenverkehr relevante Sehbeeintr\u00e4chtigung. Zus\u00e4tzliche Atropinisierung hat keinen Einfluss auf die Blendempfindlichkeit.<\/jats:p><jats:p>\n          Schlussfolgerung DIMS-Brillengl\u00e4ser sind sicher im Stra\u00dfenverkehr und verursachen keine relevante Beeintr\u00e4chtigung des Sehens, auch nicht unter Einfluss von 0,01% Atropin.\n\t\t\t\t\tDIMS-Brillengl\u00e4ser sind daher auch bei der Behandlung von progressiven Myopien in der Kombinationstherapie mit Atropin sicher.<\/jats:p>","DOI":"10.1055\/a-1930-7116","type":"journal-article","created":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T00:54:10Z","timestamp":1661475250000},"page":"1197-1205","source":"Crossref","is-referenced-by-count":10,"title":["Sicherheit von Brillengl\u00e4sern mit DIMS-Technologie und Atropin in der Kombinationstherapie der Myopieprogression"],"prefix":"10.1055","volume":"239","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5006-7420","authenticated-orcid":false,"given":"Hakan","family":"Kaymak","sequence":"additional","affiliation":[{"name":"Internationale Innovative Ophthalmochirurgie (I.\u200aI.\u200aO.), D\u00fcsseldorf, Deutschland"},{"name":"Institut f\u00fcr Experimentelle Ophthalmologie, Universit\u00e4t des Saarlandes, Homburg\/Saar, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann-Isabel","family":"Mattern","sequence":"additional","affiliation":[{"name":"Internationale Innovative Ophthalmochirurgie (I.\u200aI.\u200aO.), D\u00fcsseldorf, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birte","family":"Graff","sequence":"additional","affiliation":[{"name":"Internationale Innovative Ophthalmochirurgie (I.\u200aI.\u200aO.), D\u00fcsseldorf, Deutschland"},{"name":"Institut f\u00fcr Experimentelle Ophthalmologie, Universit\u00e4t des Saarlandes, Homburg\/Saar, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9488-6938","authenticated-orcid":false,"given":"Kai","family":"Neller","sequence":"additional","affiliation":[{"name":"Internationale Innovative Ophthalmochirurgie (I.\u200aI.\u200aO.), D\u00fcsseldorf, Deutschland"},{"name":"Institut f\u00fcr Experimentelle Ophthalmologie, Universit\u00e4t des Saarlandes, Homburg\/Saar, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Achim","family":"Langenbucher","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Experimentelle Ophthalmologie, Universit\u00e4t des Saarlandes, Homburg\/Saar, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9701-8204","authenticated-orcid":false,"given":"Berthold","family":"Seitz","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Augenheilkunde, Universit\u00e4tsklinikum des Saarlandes UKS Homburg\/Saar, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hartmut","family":"Schwahn","sequence":"additional","affiliation":[{"name":"Internationale Innovative Ophthalmochirurgie (I.\u200aI.\u200aO.), D\u00fcsseldorf, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,10,18]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1167\/iovs.62.5.3","article-title":"IMI Risk Factors for Myopia","volume":"62","author":"I G Morgan","year":"2021","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1111\/j.1475-1313.2005.00298.x","article-title":"Myopia and associated pathological complications","volume":"25","author":"S-M Saw","year":"2005","journal-title":"Ophthalmic Physiol Opt"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/j.ophtha.2018.05.029","article-title":"Low-Concentration Atropine for Myopia Progression (LAMP) Study: A Randomized, Double-Blinded, Placebo-Controlled Trial of 0.05\u200a%, 0.025\u200a%, and 0.01\u200a% Atropine Eye Drops in Myopia\n\t\t\t\t\tControl","volume":"126","author":"J C Yam","year":"2019","journal-title":"Ophthalmology"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1007\/s00347-019-0874-6","article-title":"Empfehlungen bei progredienter Myopie im Kindes- und Jugendalter: Stellungnahme von DOG und BVA. Stand Dezember 2018","volume":"116","author":"Berufsverband der Augen\u00e4rzte Deutschlands e.\u200aV.","year":"2019","journal-title":"Ophthalmologe"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"2211","DOI":"10.1007\/s00417-018-4112-8","article-title":"Short-term effects of low-concentration atropine eye drops on pupil size and accommodation in young adult subjects","volume":"256","author":"H Kaymak","year":"2018","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00417-021-05254-5","article-title":"A retrospective analysis of the therapeutic effects of 0.01\u200a% atropine on axial length growth in children in a real-life clinical setting","author":"H Kaymak","year":"2021","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1016\/j.ophtha.2021.10.002","article-title":"Three-Year Clinical Trial of Low-Concentration Atropine for Myopia Progression (LAMP) Study: Continued Versus Washout: Phase 3 Report","volume":"129","author":"J C Yam","year":"2022","journal-title":"Ophthalmology"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"7077","DOI":"10.1167\/iovs.12-10565","article-title":"Retardation of myopia in Orthokeratology (ROMIO) study: a 2-year randomized clinical trial","volume":"53","author":"P Cho","year":"2012","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1111\/opo.12332","article-title":"Studies using concentric ring bifocal and peripheral add multifocal contact lenses to slow myopia progression in school-aged children: a meta-analysis","volume":"37","author":"S M Li","year":"2017","journal-title":"Ophthalmic Physiol Opt"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1136\/bjophthalmol-2018-313739","article-title":"Defocus Incorporated Multiple Segments (DIMS) spectacle lenses slow myopia progression: a 2-year randomised clinical trial","volume":"104","author":"C SY Lam","year":"2020","journal-title":"Br J Ophthalmol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1171","DOI":"10.1136\/bjophthalmol-2020-318367","article-title":"One-year myopia control efficacy of spectacle lenses with aspherical lenslets","volume":"106","author":"J Bao","year":"2022","journal-title":"Br J Ophthalmol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1280","DOI":"10.1007\/s00347-021-01452-y","article-title":"Myopietherapie und Prophylaxe mit \u201cDefocus Incorporated Multiple Segments\u201d-Brillengl\u00e4sern","volume":"118","author":"H Kaymak","year":"2021","journal-title":"Ophthalmologe"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/j.ajo.2019.12.002","article-title":"The Adaptation and Acceptance of Defocus Incorporated Multiple Segment Lens for Chinese Children","volume":"211","author":"Y Lu","year":"2020","journal-title":"Am J Ophthalmol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1167\/tvst.9.9.11","article-title":"Effect of Defocus Incorporated Multiple Segments Spectacle Lens Wear on Visual Function in Myopic Chinese Children","volume":"9","author":"C SY Lam","year":"2020","journal-title":"Trans Vis Sci Tech"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"667329","DOI":"10.3389\/fnins.2021.667329","article-title":"Influence of Lenslet Configuration on Short-Term Visual Performance in Myopia Control Spectacle Lenses","volume":"15","author":"X Li","year":"2021","journal-title":"Front Neurosci"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"12750","DOI":"10.1038\/s41598-020-69710-8","article-title":"Efficacy of combined orthokeratology and 0.01\u200a% atropine solution for slowing axial elongation in children with myopia: a 2-year randomised trial","volume":"10","author":"N Kinoshita","year":"2020","journal-title":"Sci Rep"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"259","DOI":"10.3390\/jcm7090259","article-title":"The Synergistic Effects of Orthokeratology and Atropine in Slowing the Progression of Myopia","volume":"7","author":"L Wan","year":"2018","journal-title":"J Clin Med"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"624472","DOI":"10.3389\/fnins.2021.624472","article-title":"The Effects of 0.01\u200a% Atropine on Adult Myopes\u02bc Contrast Sensitivity","volume":"15","author":"Z Cheng","year":"2021","journal-title":"Front Neurosci"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1007\/s00347-006-1330-y","article-title":"Verkehrsophthalmologie. Fahreignungsbegutachtung im Stra\u00dfenverkehr","volume":"103","author":"B Lachenmayr","year":"2006","journal-title":"Ophthalmologe"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1111\/opo.12725","article-title":"Optical and imaging properties of a novel multi-segment spectacle lens designed to slow myopia progression","volume":"40","author":"M Jaskulski","year":"2020","journal-title":"Ophthalmic Physiol Opt"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"e000971","DOI":"10.1136\/bmjophth-2022-000971","article-title":"Vision tests on spectacle lenses and contact lenses for optical myopia correction: a pilot study","volume":"7","author":"H Kaymak","year":"2022","journal-title":"BMJ Open Ophthalmology"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"175","DOI":"10.3758\/BF03193146","article-title":"G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences","volume":"39","author":"F Faul","year":"2007","journal-title":"Behav Res Methods"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1007\/s00417-006-0474-4","article-title":"The Freiburg Visual Acuity Test-variability unchanged by post-hoc re-analysis","volume":"245","author":"M Bach","year":"2007","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"4861","DOI":"10.1167\/iovs.10-5154","article-title":"The effect of presbyopic vision corrections on nighttime driving performance","volume":"51","author":"B S Chu","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"3319","DOI":"10.1167\/iovs.17-21589","article-title":"Peripheral Design of Progressive Addition Lenses and the Lag of Accommodation in Myopes","volume":"58","author":"T Schilling","year":"2017","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"672","DOI":"10.1097\/01.opx.0000232818.37832.ee","article-title":"Visual acuity and optical parameters in progressive-power lenses","volume":"83","author":"E A Villegas","year":"2006","journal-title":"Optom Vis Sci"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"354","DOI":"10.3758\/BF03206498","article-title":"Subordinate-level categorization relies on high spatial frequencies to a greater degree than basic-level categorization","volume":"67","author":"C A Collin","year":"2005","journal-title":"Percept Psychophys"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"80","DOI":"10.4274\/tjo.93763","article-title":"Factors Affecting Contrast Sensitivity in Healthy Individuals: A Pilot Study","volume":"47","author":"A S Karatepe","year":"2017","journal-title":"Turk J Ophthalmol"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"1195","DOI":"10.1007\/s00347-011-2488-5","article-title":"Pr\u00fcfung des Kontrast- oder\u00a0D\u00e4mmerungssehens","volume":"108","author":"Deutsche Ophthalmologische Gesellschaft","year":"2011","journal-title":"Ophthalmologe"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1016\/0014-4886(82)90169-8","article-title":"Gaze latency: Variable interactions of head and eye latency","volume":"75","author":"W H Zangemeister","year":"1982","journal-title":"Exp Neurol"}],"container-title":["Klinische Monatsbl\u00e4tter f\u00fcr Augenheilkunde"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1930-7116.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,18]],"date-time":"2022-10-18T22:36:41Z","timestamp":1666132601000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1930-7116"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,25]]},"references-count":30,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2022,10,18]]},"published-print":{"date-parts":[[2022,10]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1930-7116","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0023-2165","1439-3999"],"issn-type":[{"value":"0023-2165","type":"print"},{"value":"1439-3999","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,8,25]]},"published":{"date-parts":[[2022,8,25]]}}}