{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T18:10:25Z","timestamp":1789409425981,"version":"build-2803163510"},"reference-count":19,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Facial Plast Surg"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objectives\u2003Our objective was to investigate changes in specific generic health-related quality-of-life (HRQoL) domains achieved by rhinoplasty, to investigate whether modifications of somatic-, psychologic-, and social-related HRQoL domains are different in patients with functional or aesthetic motivation for rhinoplasty, and to investigate if HRQoL changes are related to a functional or an aesthetic nasal improvement.<\/jats:p><jats:p>\n          Study Design\u2003This was a prospective study with 1 year of follow-up.<\/jats:p><jats:p>\n          Methods\u2003Fifty-four consecutive Caucasian patients submitted to rhinoplasty were evaluated with 36-item Short Form Health Survey (SF-36) and EuroQuality-of-Life 5 Domain (EQ-5D) questionnaires. To correlate changes in generic HRQoL with functional and aesthetic modifications achieved by rhinoplasty, evaluation of patients also included assessment of Peak Nasal Inspiratory Flow and Nasal Obstruction Symptom Evaluation, Visual Analogue Scale for nasal airway obstruction (NAO), and Rhinoplasty Outcome Evaluation scores.<\/jats:p><jats:p>Modifications in each generic HRQoL health-domain were analyzed to investigate the possible relation with motivation for surgery and with functional or aesthetic improvement.<\/jats:p><jats:p>\n          Results\u2003There was a significant improvement in EQ-5D (p\u2009&lt;\u20090.001), EQ-5D VAS (p\u2009=\u20090.002) and in the SF-36 domains of general health (p\u2009&lt;\u20090.001), energy (p\u2009&lt;\u20090.001), physical functioning (p\u2009&lt;\u20090.001), physical limitation (p\u2009=\u20090.005), pain (p\u2009=\u20090.003), and well-being (p\u2009=\u20090.018). Improvement was significant in groups of patients with NAO or in whom a septoplasty was performed and was associated with patient-reported functional improvement. There was a significant improvement in health change (p\u2009&lt;\u20090.001), verified in all groups of patients.<\/jats:p><jats:p>\n          Conclusions\u2003This prospective study with long-term results demonstrates that rhinoplasty significantly improves most domains of generic HRQoL. This improvement is associated with patient-reported functional improvement. Emotional limitation and social functioning are not significantly changed by rhinoplasty.<\/jats:p><jats:p>\n          Level of Evidence:\u2003IV.<\/jats:p>","DOI":"10.1055\/a-1932-8563","type":"journal-article","created":{"date-parts":[[2022,8,29]],"date-time":"2022-08-29T23:15:22Z","timestamp":1661814922000},"page":"164-172","source":"Crossref","is-referenced-by-count":6,"title":["Generic Health-Related Quality-of-Life Changes after Rhinoplasty: A Prospective Study with Long-Term Results"],"prefix":"10.1055","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1158-9853","authenticated-orcid":false,"given":"Rui","family":"Xavier","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Hospital Luz Arrabida, Porto, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4655-4987","authenticated-orcid":false,"given":"Sofia","family":"Azeredo-Lopes","sequence":"additional","affiliation":[{"name":"CHRC, NOVA Medical School | Faculdade de Ci\u00eancias M\u00e9dicas, NMS|FCM, Universidade Nova de Lisboa, Lisboa, Portugal"},{"name":"Department of Statistics and Operational Research, Faculdade de Ci\u00eancias, Universidade de Lisboa, Lisboa, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk-Jan","family":"Menger","sequence":"additional","affiliation":[{"name":"University of Utrecht, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrique Cyrne","family":"de Carvalho","sequence":"additional","affiliation":[{"name":"Instituto de Ci\u00eancias Biom\u00e9dicas Abel Salazar, Universidade do Porto, Porto, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Spratley","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina da Universidade do Porto, Centro Hospitalar e Universit\u00e1rio S. Jo\u00e3o and Centro de Investiga\u00e7\u00e3o em Tecnologias e Servi\u00e7os de Sa\u00fade (CINTESIS), Porto, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,12,9]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1097\/00005650-199206000-00002","article-title":"The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection","volume":"30","author":"J E Ware Jr","year":"1992","journal-title":"Med Care"},{"issue":"03","key":"ref2","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0168-8510(90)90421-9","article-title":"EuroQol\u2013a new facility for the measurement of health-related quality of life","volume":"16","author":"EuroQol Group","year":"1990","journal-title":"Health Policy"},{"key":"ref3","volume-title":"Summary and discussion of MOS measures. 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Yamasaki","year":"2019","journal-title":"Laryngoscope"},{"issue":"01","key":"ref13","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1002\/lary.23628","article-title":"Effect of turbinate surgery in rhinoseptoplasty on quality-of-life and acoustic rhinometry outcomes: a randomized clinical trial","volume":"123","author":"M Lavinsky-Wolff","year":"2013","journal-title":"Laryngoscope"},{"issue":"01","key":"ref14","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1002\/lary.26831","article-title":"Partial inferior turbinectomy in rhinoseptoplasty has no effect in quality-of-life outcomes: a randomized clinical trial","volume":"128","author":"B H de Moura","year":"2018","journal-title":"Laryngoscope"},{"issue":"01","key":"ref15","first-page":"57","article-title":"Assessment of patient's benefit from rhinoplasty","volume":"34","author":"E J Stewart","year":"1996","journal-title":"Rhinology"},{"issue":"05","key":"ref16","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1055\/s-0041-1725174","article-title":"Quality of life after rhinoplasty: a prospective study","volume":"37","author":"N A Papadopulos","year":"2021","journal-title":"Facial Plast Surg"},{"issue":"05","key":"ref17","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1055\/s-0037-1606572","article-title":"Quality of life-changes after rhinoplasty","volume":"33","author":"R Niehaus","year":"2017","journal-title":"Facial Plast Surg"},{"issue":"09","key":"ref18","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1002\/lary.26517","article-title":"Quality of life of patients who underwent aesthetic rhinoplasty: 100 cases assessed with the Glascow Benefit Inventory","volume":"127","author":"D 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