{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T03:50:51Z","timestamp":1762660251933},"reference-count":25,"publisher":"Georg Thieme Verlag KG","issue":"11","license":[{"start":{"date-parts":[[2022,8,30]],"date-time":"2022-08-30T00:00:00Z","timestamp":1661817600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"endo-TAGSS, LLC"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background and study aims\u2002A percutaneous intragastric trocar (PIT) enables intraluminal use of laparoscopic tools and helps overcome traditional limitations of endoscopy. The aim of this study was to determine the efficacy of using a PIT to perform an anti-reflux stapling procedure.<\/jats:p><jats:p>\n          Materials and methods\u2002Trocars were placed in four animals and an articulating stapler was used to perform fundoplication under endoscopic guidance. Animals were monitored for 14 days post-procedure. Functional lumen imaging of the esophagogastric junction (EGJ) was performed at baseline, immediately post-intervention, and at 14 days. <\/jats:p><jats:p>\n          Results\u2002The procedure was successful in all animals who survived to day 14 without distress or significant adverse events. Baseline EGJ distensibility was 5.0\u200a\u00b1\u200a1.2\u200amm2\/mmHg, 2.7\u200a\u00b1\u200a0.7\u200amm2\/mmHg post-procedurally, and 3.0\u200a\u00b1\u200a0.8mm2\/mmHg on day 14.\u200aAverage change in distensibility pre- and post-procedure was \u20132.3\u200a\u00b1\u200a1.8\u200amm2\/mmHg (95\u200a% confidence interval [CI] \u20130.5 to 5.1, P\u200a=\u200a0.08) while change in pre- and day 14 distensibility was \u20132.0\u200a\u00b1\u200a1.4\u200amm2\/mmHg (95\u200a% CI \u20130.1 to 4.2, P\u200a=\u200a0.06).<\/jats:p><jats:p>\n          Conclusions\u2002An intragastric trocar allows for use of large-diameter laparoscopic instruments to safely and effectively perform endoluminal fundoplication with anti-reflux properties that persist for at least 14 days. <\/jats:p>","DOI":"10.1055\/a-1933-6573","type":"journal-article","created":{"date-parts":[[2022,8,30]],"date-time":"2022-08-30T23:03:30Z","timestamp":1661900610000},"page":"E1508-E1513","source":"Crossref","is-referenced-by-count":2,"title":["Use of an intragastric trocar to perform a novel stapling procedure for reflux disease"],"prefix":"10.1055","volume":"10","author":[{"given":"Andrew C.","family":"Storm","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, United States"},{"name":"Developmental Endoscopy Unit, Mayo Clinic, Rochester, Minnesota, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jad P.","family":"AbiMansour","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aliana","family":"Bofill-Garcia","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tala","family":"Mahmoud","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Babusai","family":"Rapaka","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristin E.","family":"Lescalleet","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barham K. 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