{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T10:36:25Z","timestamp":1789468585075,"version":"build-2803163510"},"reference-count":24,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg G Grosstiere Nutztiere"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Ziel Erfassung des tier\u00e4rztlichen Meinungsbildes zur Equinen Lyme-Borreliose<\/jats:p><jats:p>\n          Material und Methoden Durch eine Befragung wurde untersucht, wie Pferdetier\u00e4rzte die Bedeutung positiver serologischer Nachweise gegen Borrelia burgdorferi (Bb-AK) und einer klinisch manifesten Lyme-Borreliose (LB) einsch\u00e4tzten sowie letztere diagnostizieren und therapieren.<\/jats:p><jats:p>\n          Ergebnisse Der Fragebogen wurde von 73 Tier\u00e4rzten (T\u00c4) ausgef\u00fcllt. 48 % der T\u00c4 erhoben nur sehr selten bis gar keine serologischen Bb-AK-Nachweise bei Pferden in ihrer Praxis, 47 % stellten gelegentlich Bb-AK fest und nur 5 % fanden h\u00e4ufig Bb-AK-Nachweise. 51 % der T\u00c4 best\u00e4tigen, dass sie bereits klinisch-manifeste LB-Erkrankungen festgestellt h\u00e4tten, w\u00e4hrend 43 % die Existenz dieser Erkrankung zwar nicht ausschlossen, aber selber keine Equine Lyme-Borreliose F\u00e4lle gesehen haben. 6 % der T\u00c4 zweifeln die Existenz einer klinischen LB beim Pferd generell an.<\/jats:p><jats:p>Im Durchschnitt wurden 159-mal im Jahr weiterf\u00fchrende diagnostische Ma\u00dfnahmen im Hinblick auf eine LB eingeleitet, und es wurden 1,4 \u00b1 1,0 F\u00e4lle von equiner LB im Jahr diagnostiziert. Als Untersuchungsmethoden zur Abkl\u00e4rung von Borreliose-Verdachtsf\u00e4llen verwendeten 68 % der T\u00c4 den \u201eindirekten Erregernachweis\u201c, 27 % sowohl den direkten als auch den indirekten Erregernachweis und 5 % verwendeten ausschlie\u00dflich den direkten Erregernachweis. Bei letzterem wurden am h\u00e4ufigsten Blut und Hautstanzen als Probenmaterial eingesandt.<\/jats:p><jats:p>Die Behandlung von Pferden mit auf eine Borrelioseerkrankung hinweisenden Laborergebnissen und als passend bewerteter, klinischer Symptomatik erfolgte durch 93 % der Tier\u00e4rzte mit Antibiotika und 7 % mit Hom\u00f6opathie. Am h\u00e4ufigsten wurde Doxycyclin (68 %) eingesetzt. Dabei erfolgte die antibiotische Behandlung \u00fcber einen Zeitraum von 3 (31 %) bis 4 (63 %) Wochen.<\/jats:p><jats:p>In Bezug auf eine m\u00f6gliche Impfung der Pferde gegen Borreliose boten 39 % der Tier\u00e4rzte diese Impfung nicht an, bei 20 % wurde sie noch nicht eingesetzt, aber auch nicht kategorisch abgelehnt und 41 % f\u00fchrten regelm\u00e4\u00dfig Borreliose-Impfungen durch.<\/jats:p><jats:p>\n          Schlussfolgerung und klinische Relevanz Das Meinungsbild von praktizierenden Pferdetier\u00e4rztinnen und Pferdetier\u00e4rzten in Deutschland zur klinischen Relevanz der equinen LB ist sehr heterogen. Einheitliche Richtlinien hinsichtlich Diagnostik- und evtl. auch Therapieempfehlungen w\u00e4ren sinnvoll, um der Unsicherheit in der Tier\u00e4rzteschaft entgegenzuwirken.<\/jats:p>","DOI":"10.1055\/a-1934-5808","type":"journal-article","created":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T23:33:55Z","timestamp":1667432035000},"page":"315-322","source":"Crossref","is-referenced-by-count":1,"title":["Tier\u00e4rztliches Meinungsbild zur Equinen Lyme-Borreliose \u2013 Ergebnisse einer Fragebogenstudie"],"prefix":"10.1055","volume":"50","author":[{"given":"Heidrun","family":"Gehlen","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Pferde, Allgemeine Chirurgie und Radiologie, Fachbereich Veterin\u00e4rmedizin, Freie Universit\u00e4t Berlin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina Sophie","family":"Inerle","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Pferde, Allgemeine Chirurgie und Radiologie, Fachbereich Veterin\u00e4rmedizin, Freie Universit\u00e4t Berlin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatrice","family":"Briese","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Pferde, Allgemeine Chirurgie und Radiologie, Fachbereich Veterin\u00e4rmedizin, Freie Universit\u00e4t Berlin"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,11,2]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"crossref","first-page":"685","DOI":"10.7326\/0003-4819-86-6-685","article-title":"Erythema chronicum migrans and Lyme arthritis: The enlarging clinical spectrum","volume":"86","author":"A C Steere","year":"1977","journal-title":"Ann Intern Med"},{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1002\/art.1780200102","article-title":"Lyme arthritis: an epidemic of oligoarticular arthritis in children and adults in three connecticut communities","volume":"20","author":"A C Steere","year":"1977","journal-title":"Arthritis & Rheumatism"},{"key":"ref3","first-page":"515","article-title":"Discovery of the Lyme disease spirochete and its relation to tick vectors","volume":"57","author":"W Burgdorfer","year":"1984","journal-title":"Yale J Biol Med"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1056\/NEJM198908313210906","article-title":"Lyme Disease","volume":"321","author":"A C Steere","year":"1989","journal-title":"N J Med"},{"issue":"03","key":"ref5","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1093\/infdis\/167.3.651","article-title":"Experimental Lyme disease in dogs produces arthritis and persistent infection","volume":"167","author":"M J Appel","year":"1993","journal-title":"J Infect Dis"},{"issue":"04","key":"ref6","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1128\/iai.65.4.1273-1285.1997","article-title":"Borrelia burgdorferi migrates into joint capsules and causes an up-regulation of Interleukin-8 in synovial membranes of dogs experimentally infected with ticks","volume":"65","author":"R K Straubinger","year":"1997","journal-title":"Infect Immun"},{"issue":"01","key":"ref7","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1128\/jcm.35.1.111-116.1997","article-title":"Persistence of Borrelia burgdorferi in experimentally infected dogs after antibiotic treatment","volume":"35","author":"R K Straubinger","year":"1997","journal-title":"J Clin Microbiol"},{"issue":"24","key":"ref8","first-page":"874","article-title":"Clinical manifestations, pathogenesis, and effect of antibiotic treatment on Lyme borreliosis in dogs","volume":"110","author":"R K Straubinger","year":"1998","journal-title":"Wien Klin Wochenschr"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1016\/j.tvjl.2017.06.005","article-title":"Serologic responses to peptides of Anaplasma phagocytophilum and Borrelia burgdorferi in dogs infested with 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Venner","year":"1996","journal-title":"Pferdeheilkunde \u2013 Equine Medicine"},{"issue":"05","key":"ref13","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1111\/evj.12122","article-title":"Is Lyme disease overdiagnosed in horses?","volume":"45","author":"J Bartol","year":"2013","journal-title":"Equine Vet J"},{"issue":"07","key":"ref14","doi-asserted-by":"publisher","first-page":"488","DOI":"10.1016\/j.jevs.2013.03.187","article-title":"Equine Lyme disease","volume":"33","author":"T J Divers","year":"2013","journal-title":"J Equine Vet Sci"},{"issue":"01","key":"ref15","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1354\/vp.37-1-68","article-title":"Experimental infection of ponies with Borrelia burgdorferi by exposure to Ixodid ticks","volume":"37","author":"Y-F Chang","year":"2000","journal-title":"Vet Pathol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/S0264-410X(99)00187-5","article-title":"Vaccination against Lyme disease with recombinant Borrelia burgdorferi outer-surface protein A (rOspA) in horses","volume":"18","author":"Y-F Chang","year":"2000","journal-title":"Vaccine"},{"key":"ref17","volume-title":"MIQ 12: Lyme-Borreliose. Qualit\u00e4tsstandards in der mikrobiologisch-infektiologischen Diagnostik","author":"V Fingerle","year":"2017","edition":"2. Aufl."},{"key":"ref18","first-page":"375","article-title":"Lyme disease in horses","volume":"23","author":"T J Divers","year":"2001","journal-title":"Comp Contin Educ Vet"},{"issue":"03\/04","key":"ref19","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1016\/j.vetmic.2005.02.006","article-title":"Antibiotic treatment of experimentally Borrelia burgdorferi-infected ponies","volume":"107","author":"Y-F Chang","year":"2005","journal-title":"Vet Microbiol"},{"issue":"02","key":"ref20","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1111\/jvim.15042","article-title":"Borrelia burgdorferi infection and Lyme Disease in North American horses: a consensus statement","volume":"32","author":"T J Divers","year":"2018","journal-title":"J Vet Intern Med"},{"issue":"04","key":"ref21","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1080\/01652176.2002.9695196","article-title":"Borrelia burgdorferi infections with special reference to horses: A review","volume":"27","author":"C M Butler","year":"2005","journal-title":"Vet Q"},{"issue":"04","key":"ref22","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/j.jevs.2009.03.002","article-title":"Perception of equine practitioners regarding the occurrence of selected equine neurologic diseases in the Northeast over a 10-year period","volume":"29","author":"B A DeVilbiss","year":"2009","journal-title":"J Equine Vet Sci"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1136\/vr.132.24.610","article-title":"Lameness associated with Borrelia burgdorferi infection in the horse","volume":"132","author":"A Browning","year":"1993","journal-title":"Vet Rec"},{"issue":"03","key":"ref24","first-page":"188","article-title":"Antworten zur Lyme-Borreliose beim Pferd","author":"Y Gall","year":"2006","journal-title":"Prakt Tierarzt"}],"container-title":["Tier\u00e4rztliche Praxis Ausgabe G: Gro\u00dftiere \/ Nutztiere"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1934-5808.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T23:34:48Z","timestamp":1667432088000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1934-5808"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":24,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2022,11,2]]},"published-print":{"date-parts":[[2022,10]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1934-5808","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1434-1220","2567-5834"],"issn-type":[{"value":"1434-1220","type":"print"},{"value":"2567-5834","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10]]}}}