{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T11:06:17Z","timestamp":1787742377811,"version":"build-2784847793"},"reference-count":23,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dtsch Med Wochenschr"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Was ist neu?<\/jats:title><jats:p>\n          Risikofaktoren f\u00fcr schwere Verl\u00e4ufe Als Risikopr\u00e4diktor wird der\n      CRB-65-Score empfohlen sowie die Ber\u00fccksichtigung instabiler Komorbidit\u00e4ten und der\n      Oxygenierung.<\/jats:p><jats:p>\n          Gruppeneinteilung der ambulant erworbenen Pneumonie Die ambulant\n      erworbene Pneumonie wird in 3 Gruppen eingeteilt: leichte Pneumonie, mittelschwere Pneumonie,\n      schwere Pneumonie. Ob ein kuratives vs. palliatives Behandlungsziel besteht, sollte fr\u00fchzeitig\n      festgelegt werden.<\/jats:p><jats:p>\n          Diagnostikempfehlung Zur Sicherung der Diagnose wird eine\n      R\u00f6ntgen-Thoraxaufnahme empfohlen, m\u00f6glichst auch im ambulanten Bereich. Alternativ kann eine Sonografie des\n      Thorax durchgef\u00fchrt werden, wobei bei negativem Befund weitere Bildgebung empfohlen wird. Streptococcus pneumoniae ist weiterhin der h\u00e4ufigste bakterielle Erreger.<\/jats:p><jats:p>\n          Therapie Die ambulant erworbene Pneumonie ist nach wie vor mit\n      hoher Morbidit\u00e4t und Letalit\u00e4t assoziiert. Eine z\u00fcgige Diagnosestellung und die umgehende\n      Einleitung einer risikoadaptierten antimikrobiellen Therapie stellen wesentliche Ma\u00dfnahmen\n      dar. In Zeiten von COVID-19, aber auch der aktuellen Influenza- und RSV-Epidemie, muss aber\n      auch mit rein viralen Pneumonien gerechnet werden. Zumindest bei COVID-19 kann h\u00e4ufig auf ein\n      Antibiotikum verzichtet werden. Antivirale und entz\u00fcndungshemmende Medikamente werden hier\n      eingesetzt.<\/jats:p><jats:p>\n          Postakuter Verlauf Patienten nach ambulant erworbener Pneumonie\n      haben eine erh\u00f6hte Akut- und Langzeitletalit\u00e4t \u2013 aufgrund von insbesondere kardiovaskul\u00e4ren\n      Ereignissen. Das Augenmerk der Forschung liegt auf verbesserter Erregererkennung, einem\n      besseren Verst\u00e4ndnis der Wirtsantwort, mit dem Potenzial der Entwicklung spezifischer\n      Therapeutika, der Rolle von Komorbidit\u00e4ten und den Langzeitfolgen der akuten\n      Erkrankung.<\/jats:p>","DOI":"10.1055\/a-1940-8944","type":"journal-article","created":{"date-parts":[[2023,3,6]],"date-time":"2023-03-06T23:32:46Z","timestamp":1678145566000},"page":"335-341","source":"Crossref","is-referenced-by-count":9,"title":["Ambulant erworbene Pneumonie"],"prefix":"10.1055","volume":"148","author":[{"given":"Alexander","family":"Seeger","sequence":"additional","affiliation":[{"name":"Med. Klinik 1 \u2013 Schwerpunkt Pneumologie und Allergologie, Universit\u00e4tsklinikum Frankfurt, Frankfurt am Main, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gernot","family":"Rohde","sequence":"additional","affiliation":[{"name":"Med. 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