{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,11,3]],"date-time":"2022-11-03T04:52:28Z","timestamp":1667451148778},"reference-count":25,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg K Kleintiere Heimtiere"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Gegenstand und Ziel Ziel der Studie war es, Daten \u00fcber den Einsatz von Antibiotika (AB) bei Hunden und Katzen in Tierarztpraxen und -kliniken in Bayern zu erheben. Dabei sollte evaluiert werden, ob sich \u00c4nderungen hinsichtlich des Antibiotikaeinsatzes nach Novellierung der Verordnung \u00fcber Tier\u00e4rztliche Hausapotheken (T\u00c4HAV) im M\u00e4rz 2018 ergeben haben.<\/jats:p><jats:p>\n          Material und Methoden Mittels zweier anonymisierter Online-Umfragen wurden 2017 und 2020 Tier\u00e4rzte\/-innen (T\u00c4) in Bayern, zu deren Patienten Hunde und Katzen z\u00e4hlen, zur Anwendung von AB sowie zur Einsch\u00e4tzung der Resistenzsituation befragt. Die Ergebnisse der beiden Umfragen wurden anschlie\u00dfend miteinander verglichen.<\/jats:p><jats:p>\n          Ergebnisse F\u00fcr 2017 konnten 238 Frageb\u00f6gen ausgewertet werden; 2020 waren es 160. Die 3 am h\u00e4ufigsten zur systemischen Therapie beim Kleintier angewendeten AB waren 2017 Amoxicillin\/Clavulans\u00e4ure (74,8 % der T\u00c4), Enrofloxacin (56,7 %) und Amoxicillin (53,4 %). 2020 wurden Amoxicillin\/Clavulans\u00e4ure (88,8 %), Amoxicillin (67,5 %) und Metronidazol (33,8 %) genannt. Die teilnehmenden T\u00c4 gaben an, signifikant weniger Cephalosporine der 3. und 4. Generation (von 20,2 % der teilnehmenden T\u00c4 in 2017 auf 9,4 % in 2020, p = 0,005) und Fluorchinolone (von 80,3 % auf 33,1 %, p &lt; 0,001) einzusetzen. Die Wahl eines AB wurde 2020 bei 83,8 % der befragten T\u00c4 durch rechtliche Vorgaben beeinflusst; weitere Einflussfaktoren waren Vertr\u00e4glichkeit (81,3 %), Applikationsart (76,9 %), Akzeptanz durch den Patienten (70,0 %) und H\u00e4ufigkeit der Anwendung (64,4 %), wobei letzterer von T\u00c4 aus der Praxis (83,8 %, p = 0,004) signifikant h\u00e4ufiger genannt wurden als von T\u00c4 aus Kliniken.<\/jats:p><jats:p>\n          Schlussfolgerung Im Vergleich zu 2017 gaben T\u00c4 2020 einen signifikant geringeren Einsatz von Fluorchinolonen und Cephalosporinen der 3. und 4. Generation bei Hund und Katze an. Diese \u00c4nderungen im Verschreibungsverhalten k\u00f6nnten Folgen der Novellierung der T\u00c4HAV sein, die ein Umwidmungsverbot sowie eine Antibiogrammpflicht dieser AB-Klassen vorgibt.<\/jats:p><jats:p>\n          Klinische Relevanz Rechtliche Vorgaben k\u00f6nnen m\u00f6glicherweise einen positiven Einfluss auf die Menge und Art der in der Kleintiermedizin eingesetzten Antibiotika haben und somit bei der Vermeidung von Antibiotikaresistenzen helfen.<\/jats:p>","DOI":"10.1055\/a-1949-0407","type":"journal-article","created":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T23:31:42Z","timestamp":1667431902000},"page":"337-347","source":"Crossref","is-referenced-by-count":0,"title":["Einfluss der Verordnung \u00fcber Tier\u00e4rztliche Hausapotheken auf den Antibiotikaeinsatz bei Hund und Katze in Bayern"],"prefix":"10.1055","volume":"50","author":[{"given":"Kaye","family":"Mohr","sequence":"additional","affiliation":[{"name":"Medizinische Kleintierklinik der Ludwig-Maximilians-Universit\u00e4t, M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirja","family":"Nolff","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Kleintierchirurgie, Tierspital Universit\u00e4t Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yury","family":"Zablotski","sequence":"additional","affiliation":[{"name":"Medizinische Kleintierklinik der Ludwig-Maximilians-Universit\u00e4t, M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Dittus","sequence":"additional","affiliation":[{"name":"Tierklinik Stadtsteinach, Stadtsteinach"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R\u00fcdiger","family":"Korbel","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr V\u00f6gel, Kleins\u00e4uger, Reptilien und Zierfische der Ludwig-Maximilians-Universit\u00e4t, M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Meyer-Lindenberg","sequence":"additional","affiliation":[{"name":"Chirurgische und Gyn\u00e4kologische Kleintierklinik der Ludwig-Maximilians-Universit\u00e4t, M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georg","family":"Wolf","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Infektionsmedizin und Zoonosen der Ludwig-Maximilians-Universit\u00e4t, M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katrin","family":"Hiss","sequence":"additional","affiliation":[{"name":"Bayerisches Landesamt f\u00fcr Gesundheit und Lebensmittelsicherheit, Erlangen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannah","family":"Peters","sequence":"additional","affiliation":[{"name":"Bayerisches Landesamt f\u00fcr Gesundheit und Lebensmittelsicherheit, Erlangen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bianka","family":"Schulz","sequence":"additional","affiliation":[{"name":"Medizinische Kleintierklinik der Ludwig-Maximilians-Universit\u00e4t, M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,11,2]]},"reference":[{"key":"ref1","volume-title":"Nobel Lecture","author":"Sir Alexander Fleming","year":"2021"},{"key":"ref6","volume-title":"GRAM: Guidance for the rational use of antimicrobials: Recommendations for dogs and cats","author":"H Brissot","year":"2016","edition":"2nd. 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