{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T07:15:23Z","timestamp":1779261323455,"version":"3.51.4"},"reference-count":10,"publisher":"Georg Thieme Verlag KG","issue":"12","license":[{"start":{"date-parts":[[2022,9,30]],"date-time":"2022-09-30T00:00:00Z","timestamp":1664496000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background and study aims\u2002Intussusception caused by intestinal polyps in patients with Peutz-Jeghers syndrome usually requires laparotomy. Patients following successful endoscopic reduction using double-balloon endoscopy (DBE) have been reported. The aim of this study was to evaluate the feasibility of endoscopic treatment of intussusception.<\/jats:p><jats:p>\n          Patients and methods\u2002We retrospectively reviewed patients who underwent DBE for intussusception due to small intestine polyps in patients with Peutz-Jeghers syndrome from January 2004 to June 2020. <\/jats:p><jats:p>\n          Results\u2002Twenty-seven (antegrade 22, retrograde 5) DBEs were performed in 19 patients with 25 sites of intussusception identified during the study period. If the intussusception remained once the endoscope reached the site, endoscopic reduction of the intussusception was performed as needed (15 sites). Ultimately, endoscopic resections (8 sites) or ischemic polypectomies (16 sites) of the polyp causing the intussusception were completed at 24 sites. Only one site could not be treated endoscopically and was treated surgically. The final per-site and per-patient success rates of endoscopic treatment were 96\u200a% (24\/25) and 95\u200a% (18\/19) respectively. Two patients developed mild acute pancreatitis and one patient developed intussusception after the procedures, both of which were treated non-operatively.<\/jats:p><jats:p>\n          Conclusions\u2002Endoscopic treatment of intussusception is feasible to avoid laparotomy in patients with Peutz-Jeghers syndrome.<\/jats:p>","DOI":"10.1055\/a-1954-0110","type":"journal-article","created":{"date-parts":[[2022,9,30]],"date-time":"2022-09-30T23:01:47Z","timestamp":1664578907000},"page":"E1583-E1588","source":"Crossref","is-referenced-by-count":10,"title":["Endoscopic treatment of intussusception due to small intestine polyps in patients with Peutz-Jeghers Syndrome"],"prefix":"10.1055","volume":"10","author":[{"given":"Kunihiko","family":"Oguro","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirotsugu","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomonori","family":"Yano","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yohei","family":"Funayama","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masafumi","family":"Kitamura","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manabu","family":"Nagayama","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keijiro","family":"Sunada","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan Kawarai","family":"Lefor","sequence":"additional","affiliation":[{"name":"Department of Surgery, Jichi Medical University, Tochigi, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hironori","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,12,15]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1136\/gut.2009.198499","article-title":"Peutz-Jeghers syndrome: a systematic review and recommendations for management","volume":"59","author":"A D Beggs","year":"2010","journal-title":"Gut"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1097\/00005176-200408000-00027","article-title":"Complications of childhood Peutz-Jeghers syndrome: implications for pediatric screening","volume":"39","author":"R Hinds","year":"2004","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.gie.2011.04.001","article-title":"Nonsurgical management of small-bowel polyps in Peutz-Jeghers syndrome with extensive polypectomy by using double-balloon endoscopy","volume":"74","author":"H Sakamoto","year":"2011","journal-title":"Gastrointest Endosc"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1111\/den.12883","article-title":"Clinical practice guideline for enteroscopy","volume":"29","author":"H Yamamoto","year":"2017","journal-title":"Digest Endosc"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"473","DOI":"10.3390\/jcm10030473","article-title":"The management of Peutz-Jeghers syndrome: European Hereditary Tumour Group (EHTG) Guideline","volume":"10","author":"A Wagner","year":"2021","journal-title":"J Clin Med"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.gie.2009.11.045","article-title":"Reduction of ileoileal intussusception by using double-balloon endoscopy in Peutz-Jeghers syndrome (with video)","volume":"72","author":"Y Miura","year":"2010","journal-title":"Gastrointest Endosc"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"40","DOI":"10.14740\/gr1130","article-title":"Successful endoscopic reduction of an ileocolonic intussusception in an adult with Peutz-Jeghers syndrome","volume":"12","author":"M A AlSamman","year":"2019","journal-title":"Gastroenterology Res"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1007\/s12328-019-00943-5","article-title":"Curative endoscopic treatment of intussusception due to a giant colonic lipoma using a wedged balloon and ligation with detachable snares","volume":"12","author":"M Okada","year":"2019","journal-title":"Clin J Gastroenterol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1055\/a-1276-6452","article-title":"Endoscopic ischemic polypectomy for small-bowel polyps in patients with Peutz-Jeghers syndrome","volume":"53","author":"T Khurelbaatar","year":"2021","journal-title":"Endoscopy"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1055\/a-0576-0566","article-title":"Small-bowel capsule endoscopy and device-assisted enteroscopy for diagnosis and treatment of small-bowel disorders: European Society of Gastrointestinal Endoscopy (ESGE) Technical Review","volume":"50","author":"E Rondonotti","year":"2018","journal-title":"Endoscopy"}],"container-title":["Endoscopy International Open"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1954-0110.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,16]],"date-time":"2022-12-16T05:30:55Z","timestamp":1671168655000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1954-0110"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,30]]},"references-count":10,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2022,12,15]]},"published-print":{"date-parts":[[2022,12]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1954-0110","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2364-3722","2196-9736"],"issn-type":[{"value":"2364-3722","type":"print"},{"value":"2196-9736","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,9,30]]},"published":{"date-parts":[[2022,9,30]]}}}