{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T07:28:40Z","timestamp":1748244520046},"reference-count":27,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg G Grosstiere Nutztiere"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Objective Research and provision of data on macrophages by cytological synovial fluid analysis and light microscopy in horses with septic arthritis<\/jats:p><jats:p>Material and methods Records of 167 synovial fluid samples were evaluated and subdivided into different groups: (1) non-septic, (2) haematogenous septic arthritis in foals and (3) traumatic\/iatrogenic septic arthritis. The effect of joint lavage on synovial fluid cytology and on the occurrence of macrophage phenotypes was investigated.<\/jats:p><jats:p>Results Regardless of aetiology and age of the horse, macrophage concentrations in synovial sepsis are decreased to a median of 5\u20136\u2005% (unaffected joints: 23.5\u2005%) and further diminished by joint lavage. Microscopic assessment led to the identification of 4 phenotypes. Morphological characteristics of type 1 showed similarities to monocytes and predominated in unaffected and in septic joints after lavage.<\/jats:p><jats:p>Conclusion and clinical relevance Macrophages are highly versatile by altering their phenotype. A morphological assessment by light microscopy is easily applicable. Type 1 presumably contributes to joint homeostasis.<\/jats:p>","DOI":"10.1055\/a-1956-5245","type":"journal-article","created":{"date-parts":[[2022,12,14]],"date-time":"2022-12-14T23:30:13Z","timestamp":1671060613000},"page":"377-385","source":"Crossref","is-referenced-by-count":1,"title":["Synovial Fluid Analysis and Microscopic Assessment of Macrophage Quantities and Morphology in Equine Septic Arthritis"],"prefix":"10.1055","volume":"50","author":[{"given":"Teresa","family":"Strootmann","sequence":"additional","affiliation":[{"name":"Department for Horses, Faculty of Veterinary Medicine, Leipzig University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingo","family":"Spitzbarth","sequence":"additional","affiliation":[{"name":"Institute for Veterinary Pathology, Faculty of Veterinary Medicine, Leipzig University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simone","family":"della Tommasa","sequence":"additional","affiliation":[{"name":"Department for Horses, Faculty of Veterinary Medicine, Leipzig University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walter","family":"Brehm","sequence":"additional","affiliation":[{"name":"Department for Horses, Faculty of Veterinary Medicine, Leipzig University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabor","family":"K\u00f6ller","sequence":"additional","affiliation":[{"name":"Department for Horses, Faculty of Veterinary Medicine, Leipzig University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonia","family":"Troillet","sequence":"additional","affiliation":[{"name":"Clinic for Horses, Faculty of Veterinary Medicine, 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Nutztiere"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1956-5245.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,10]],"date-time":"2024-10-10T10:56:08Z","timestamp":1728557768000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1956-5245"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":27,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2022,12,14]]},"published-print":{"date-parts":[[2022,12]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1956-5245","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1434-1220","2567-5834"],"issn-type":[{"type":"print","value":"1434-1220"},{"type":"electronic","value":"2567-5834"}],"subject":[],"published":{"date-parts":[[2022,12]]}}}