{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T01:43:38Z","timestamp":1783820618171,"version":"3.55.0"},"reference-count":27,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2022,10,13]],"date-time":"2022-10-13T00:00:00Z","timestamp":1665619200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:p>\n            Objective\u2003Antenatal depression (AD) has been considered a risk factor for cesarean delivery (CD); however, the supporting data are inconsistent. We used a large, nationally representative dataset to evaluate whether there is an association between AD and CD among women delivering for the first time.<\/jats:p><jats:p>\n            Study Design\u2003We utilized the 2016 to 2019 Multistate Pregnancy Risk Assessment Monitoring System (PRAMS) from the Centers for Disease Control. First-time parturients who reported depression in the 3 months prior to or at any point during their recent pregnancy were compared with those who did not. The mode of delivery was obtained through the birth certificate. Maternal demographics, pregnancy characteristics, and delivery characteristics were compared by the report of AD using bivariable analyses. Population-weighted multivariable regression was performed, adjusting for maternal age, race\/ethnicity, insurance, pregnancy complications, preterm birth, and body mass index (BMI).<\/jats:p><jats:p>\n            Results\u2003Of the 61,605 people who met the inclusion criteria, 18.3% (n\u2009=\u200911,896) reported AD and 29.8% (n\u2009=\u200919,892) underwent CD. Parturients with AD were younger, more likely to be non-Hispanic white, publicly insured, use tobacco in pregnancy, deliver earlier, have lower levels of education, higher BMIs, and more medical comorbidities (hypertension and diabetes). After adjustment for these differences, there was no difference in risk of CD between those with AD compared with those without (adjusted odds ratio: 1.04; 95% confidence interval: 0.97\u20131.13).<\/jats:p><jats:p>\n            Conclusion\u2003In a large, population-weighted, nationally representative sample of first-time parturients, there was no association between AD and CD.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/a-1960-2919","type":"journal-article","created":{"date-parts":[[2022,10,13]],"date-time":"2022-10-13T22:56:46Z","timestamp":1665701806000},"page":"356-362","source":"Crossref","is-referenced-by-count":2,"title":["The Association of Antenatal Depression and Cesarean Delivery among First-Time Parturients: A Population-Based Study"],"prefix":"10.1055","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8737-407X","authenticated-orcid":false,"given":"Nina K.","family":"Ayala","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine, Women and Infants Hospital of Rhode Island, Providence, Rhode Island"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Schlichting","sequence":"additional","affiliation":[{"name":"Hassenfeld Child Health Innovation Institute, Brown University School of Public Health, Providence, Rhode Island"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam K.","family":"Lewkowitz","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine, Women and Infants Hospital of Rhode Island, Providence, Rhode Island"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martha B.","family":"Kole-White","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine, Women and Infants Hospital of Rhode Island, Providence, Rhode Island"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annie","family":"Gjelsvik","sequence":"additional","affiliation":[{"name":"Hassenfeld Child Health Innovation Institute, Brown University School of Public Health, Providence, Rhode Island"},{"name":"Department of Epidemiology, Brown University School of Public Health, Providence, Rhode Island"},{"name":"Department of Pediatrics, Alpert Medical School of Brown University, Providence, Rhode Island"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karine","family":"Monteiro","sequence":"additional","affiliation":[{"name":"Rhode Island Department of Health, Providence, Rhode Island"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siraj","family":"Amanullah","sequence":"additional","affiliation":[{"name":"Hassenfeld Child Health Innovation Institute, Brown University School of Public Health, Providence, Rhode Island"},{"name":"Department of Pediatrics, Alpert Medical School of Brown University, Providence, Rhode Island"},{"name":"Department of Emergency Medicine, Alpert Medical School of Brown University, Providence, Rhode Island"},{"name":"Department of Health Services, Policy and Practice, Brown School of Public Health, Providence, Rhode Island"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,11,15]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1097\/AOG.0000000000003291","article-title":"Recorded diagnoses of depression during delivery hospitalizations in the United States, 2000-2015","volume":"133","author":"S C Haight","year":"2019","journal-title":"Obstet Gynecol"},{"issue":"05","key":"ref2","doi-asserted-by":"crossref","first-page":"e208","DOI":"10.1097\/AOG.0000000000002927","article-title":"ACOG Committee Opinion No. 757: screening for perinatal depression","volume":"132","author":"ACOG Committee Opinion 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development: an organizational perspective","volume":"80","author":"S L Toth","year":"2009","journal-title":"Child Dev"},{"issue":"05","key":"ref6","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1097\/AOG.0b013e31823294da","article-title":"Homicide and suicide during the perinatal period: findings from the National Violent Death Reporting System","volume":"118","author":"C L Palladino","year":"2011","journal-title":"Obstet Gynecol"},{"issue":"07","key":"ref7","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1111\/jog.12683","article-title":"Effect of depressive and anxiety symptoms during pregnancy on risk of obstetric interventions","volume":"41","author":"H Bayrampour","year":"2015","journal-title":"J Obstet Gynaecol Res"},{"issue":"05","key":"ref8","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1097\/00006842-200109000-00017","article-title":"Antepartum depressive symptomatology is associated with adverse obstetric and neonatal 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Ayala","year":"2022","journal-title":"R I Med J (2013)"},{"issue":"07","key":"ref15","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1111\/j.1471-0528.1993.tb14228.x","article-title":"The effect of anxiety and depression during pregnancy on obstetric complications","volume":"100","author":"M R Perkin","year":"1993","journal-title":"Br J Obstet Gynaecol"},{"issue":"04","key":"ref16","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1111\/j.1552-6909.2009.01034.x","article-title":"Are maternal cortisol levels related to preterm birth?","volume":"38","author":"C Giurgescu","year":"2009","journal-title":"J Obstet Gynecol Neonatal Nurs"},{"issue":"S 01","key":"ref17","doi-asserted-by":"crossref","first-page":"S60","DOI":"10.1016\/S0049-3848(15)50446-5","article-title":"Adverse obstetric and neonatal outcomes in women with mental disorders","volume":"135","author":"S Hoirisch-Clapauch","year":"2015","journal-title":"Thromb 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