{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T04:46:13Z","timestamp":1788410773932,"version":"build-2803163510"},"reference-count":46,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Sports Med"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Baroreflex sensitivity (BRS) is a measure of cardiovagal baroreflex and is lower\n                    in normobaric and hypobaric hypoxia compared to normobaric normoxia. The aim of\n                    this study was to assess the effects of hypobaria on BRS in normoxia and\n                    hypoxia. Continuous blood pressure and ventilation were recorded in eighteen\n                    seated participants in normobaric normoxia (NNx), hypobaric normoxia (HNx),\n                    normobaric hypoxia (NHx) and hypobaric hypoxia (HHx). Barometric pressure was\n                    matched between NNx vs. NHx (723\u00b14\u2009mmHg) and HNx vs. HHx\n                    (406\u00b14 vs. 403\u00b15\u2009mmHg). Inspired oxygen pressure\n                        (PiO2) was matched between NNx vs. HNx (141.2\u00b10.8 vs.\n                    141.5\u00b11.5\u2009mmHg) and NHx vs. HHx (75.7\u00b10.4 vs.\n                    74.3\u00b11.0\u2009mmHg). BRS was assessed using the sequence method. BRS\n                    significantly decreased in HNx, NHx and HHx compared to NNx. Heart rate, mean\n                    systolic and diastolic blood pressures did not differ between conditions. There\n                    was the specific effect of hypobaria on BRS in normoxia (BRS was lower in HNx\n                    than in NNx). The hypoxic and hypobaric effects do not add to each other\n                    resulting in comparable BRS decreases in HNx, NHx and HHx. BRS decrease under\n                    low barometric pressure requires future studies independently controlling\n                        O2 and CO2 to identify central and peripheral\n                    chemoreceptors\u2019 roles.<\/jats:p>","DOI":"10.1055\/a-1960-3407","type":"journal-article","created":{"date-parts":[[2022,12,2]],"date-time":"2022-12-02T00:00:11Z","timestamp":1669939211000},"page":"177-183","source":"Crossref","is-referenced-by-count":11,"title":["Both Hypoxia and Hypobaria Impair Baroreflex Sensitivity but through\n                    Different Mechanisms"],"prefix":"10.1055","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6791-2002","authenticated-orcid":false,"given":"Nicolas","family":"Bourdillon","sequence":"additional","affiliation":[{"name":"ISSUL, institute of sports sciences, Universit\u00e9 de Lausanne,\n                    Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathias Rolland","family":"Aebi","sequence":"additional","affiliation":[{"name":"ISSUL, institute of sports sciences, Universit\u00e9 de Lausanne,\n                    Lausanne, Switzerland"},{"name":"Wissenschaft & Technologie, armasuisse, Thun,\n                    Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bengt","family":"Kayser","sequence":"additional","affiliation":[{"name":"ISSUL, institute of sports sciences, Universit\u00e9 de Lausanne,\n                    Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Bron","sequence":"additional","affiliation":[{"name":"ISSUL, institute of sports sciences, Universit\u00e9 de Lausanne,\n                    Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregoire P","family":"Millet","sequence":"additional","affiliation":[{"name":"ISSUL, University of Lausanne, Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,12,1]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"975","DOI":"10.3357\/ASEM.2331.2008","article-title":"Critique of the equivalent air altitude model","volume":"79","author":"J Conkin","year":"2008","journal-title":"Aviat Space Environ Med"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1152\/japplphysiol.00067.2012","article-title":"Point: Counterpoint: Hypobaric hypoxia induces\/does not induce different\n                    responses from normobaric hypoxia","volume":"112","author":"G P Millet","year":"2012","journal-title":"J Appl Physiol (1985)"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"e114418","DOI":"10.1371\/journal.pone.0114418","article-title":"Comparison of \u201cLive High-Train Low\u201d in normobaric versus\n                    hypobaric hypoxia","volume":"9","author":"J J 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