{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T22:26:22Z","timestamp":1779143182849,"version":"3.51.4"},"reference-count":48,"publisher":"Georg Thieme Verlag KG","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fortschr Neurol Psychiatr"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Seit einigen Jahren steigt die Inzidenz der Syphilis und neuroluetischer\n                    Krankheitsbilder. Damit gewinnen auch Tabes dorsalis und progressive Paralyse\n                    wieder an Relevanz in der Neurologie. Um das Verst\u00e4ndnis der\n                    \u00c4tiologie dieser Krankheitsbilder wurde in den letzten beiden\n                    Jahrzehnten des 19. Jahrhunderts gerade auch in der deutschen Nervenheilkunde\n                    eine hitzige Debatte gef\u00fchrt, der sogenannte\n                    \u201aTabes-Syphilis-Streit\u2018. Wilhelm Erb hatte 1879 in einem viel\n                    beachteten Vortrag die deutsche Nerven\u00e4rzteschaft dazu aufgerufen,\n                    endlich zielstrebig die Kl\u00e4rung der Ursache der Tabes dorsalis\n                    anzugehen. Er selbst postulierte v.\u2009a. auf Grund von\n                    Krankheitsstatistiken eine vorherige syphilitische Infektion als\n                    haupts\u00e4chliches Moment. Die L\u00f6sung dieser Frage dr\u00e4ngte,\n                    denn der Anteil der Patienten in den psychiatrischen Anstalten, die an\n                    progressiver Paralyse litten, bei der enge Parallelen zur Tabes gesehen wurden,\n                    nahm rapide zu. Die Berliner Nerven\u00e4rzte Carl Westphal, Ernst Julius\n                    Remak, Martin Bernhardt und Ernst Victor von Leyden empfanden Erbs These als\n                    Fehdehandschuh. Sie sahen die Ursachen von Tabes und progressiver Paralyse in\n                    sozialen Verelendungsprozessen wie feucht-kalten Wohnverh\u00e4ltnissen, in\n                    k\u00f6rperlich einseitigen Arbeits\u00fcberlastungen oder in den\n                    Strapazen von Soldaten im Heer. Als Anlass einer traumatischen Tabes nahmen sie\n                    Ersch\u00fctterungen oder Prellungen an. Der Leipziger Nervenarzt Paul Julius\n                    M\u00f6bius sprach als Erster zwischen 1890 und 1897 aus, dass die einzige\n                    Ursache von Tabes und progressiver Paralyse eine vorherige Syphilis sei.\n                    Konsequent schloss er alle anderen \u00e4tiologischen Theorien aus. Vor allem\n                    die bakteriologische und mikrobiologische Forschung der Folgejahre gab\n                    M\u00f6bius recht. Somit konnten 40 Jahre nach Erbs Vortrag neben\n                    diagnostischen auch therapeutische Verfahren gezielt entwickelt und angewendet\n                    werden.<\/jats:p>","DOI":"10.1055\/a-1972-3201","type":"journal-article","created":{"date-parts":[[2023,1,5]],"date-time":"2023-01-05T01:20:13Z","timestamp":1672881613000},"page":"494-501","source":"Crossref","is-referenced-by-count":2,"title":["Der \u201aTabes-Syphilis-Streit\u2018 Ein Disput \u00fcber\n                    die Ursache der Tabes dorsalis und der progressiven Paralyse am Ende des 19.\n                    Jahrhunderts"],"prefix":"10.1055","volume":"92","author":[{"given":"Holger","family":"Steinberg","sequence":"additional","affiliation":[{"name":"Forschungsstelle f\u00fcr die Geschichte der Psychiatrie, Klinik und\n                    Poliklinik f\u00fcr Psychiatrie und Psychotherapie, Medizinische\n                    Fakult\u00e4t der Universit\u00e4t Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,1,4]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1080\/0964704X.2020.1852055","article-title":"Wilhelm Erb (1840-1921), an influential German founder of neurology in the\n                    nineteenth century","volume":"30","author":"B. 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