{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T07:52:01Z","timestamp":1787730721061,"version":"build-2784847793"},"reference-count":44,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Monbl Augenheilkd"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Bei chronisch progredienten und therapierbaren Erkrankungen ist die Adh\u00e4renz der Patienten ausschlaggebend f\u00fcr den Krankheitsverlauf und entscheidet ma\u00dfgeblich \u00fcber den Therapieerfolg.\n          Dabei ist nicht nur eine geringe Adh\u00e4renz bei der Medikamenteneinnahme problematisch, sondern auch beim Einhalten der empfohlenen Nachuntersuchungen. Eine akkurate Einsch\u00e4tzung der Adh\u00e4renz\n          ist insbesondere bei Glaukompatienten nur schwer m\u00f6glich aufgrund der Darreichungsform als Augentropfen bei den meisten drucksenkenden Medikamenten. In der Literatur l\u00e4sst sich eine gro\u00dfe\n          Variabilit\u00e4t an Angaben f\u00fcr die Adh\u00e4renz von Glaukompatienten finden. Die meisten Studien berichten eine durchschnittliche Arzneimitteladh\u00e4renz von ungef\u00e4hr 70% mit einem Patientenanteil von\n          um die 50% mit einer guten Adh\u00e4renz (mindestens 80% der Medikation wird wie geplant appliziert). Des Weiteren landen 6,8\u200a\u2013\u200a31,4% der Augentropfen nicht im Auge, wodurch noch weniger\n          Wirkstoff einen therapeutischen Effekt erzielen kann. Auch weisen Glaukompatienten eine geringe Persistenz und Adh\u00e4renz in puncto Kontrolluntersuchungen auf. Da ein bestehender Diabetes das\n          Risiko f\u00fcr ein POAG und sekund\u00e4re Glaukomformen steigert und Diabetiker eine besonders niedrige Adh\u00e4renz aufweisen, stellte sich die Frage, ob eine Diabetesdiagnose mit einer erniedrigten\n          Adh\u00e4renz bei Glaukompatienten assoziiert ist. Bisherige Studien fanden keine signifikante Assoziation zwischen einer Diabeteskomorbidit\u00e4t und einer erniedrigten Adh\u00e4renz bei\n          Glaukompatienten, allerdings wurde ein signifikanter Einfluss von einem erh\u00f6hten HbA1c-Wert auf die Adh\u00e4renz bei Glaukompatienten in einer Studie festgestellt. Dieser Zusammenhang\n          muss allerdings noch in Studien mit gr\u00f6\u00dferen Stichproben genauer untersucht werden.<\/jats:p>","DOI":"10.1055\/a-1975-2396","type":"journal-article","created":{"date-parts":[[2022,11,10]],"date-time":"2022-11-10T00:20:37Z","timestamp":1668039637000},"page":"136-141","source":"Crossref","is-referenced-by-count":1,"title":["Beeinflusst Diabetes mellitus die Adh\u00e4renz von Glaukompatienten?"],"prefix":"10.1055","volume":"240","author":[{"given":"Qifan Felix","family":"Zhao","sequence":"additional","affiliation":[{"name":"Glaukomsprechstunde, Augenklinik und Poliklinik des Klinikums der Universit\u00e4t M\u00fcnchen, M\u00fcnchen, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Hirneiss","sequence":"additional","affiliation":[{"name":"Glaukomsprechstunde, Augenklinik und Poliklinik des Klinikums der Universit\u00e4t M\u00fcnchen, M\u00fcnchen, 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