{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T23:34:27Z","timestamp":1772667267191,"version":"3.50.1"},"reference-count":24,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2022,11,14]],"date-time":"2022-11-14T00:00:00Z","timestamp":1668384000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Region of Southern Denmark","award":["16\/9780 & 19\/37100"],"award-info":[{"award-number":["16\/9780 & 19\/37100"]}]},{"name":"The Danish Colitis and Crohn\u2019s Association"},{"name":"Research Council Lillebaelt Hospital"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background and study aims\u2002Recent evidence supports the use of pan-enteric capsule endoscopy (CE) for the diagnosis and follow-up of Crohn\u2019s disease (CD). The aim of this study was to examine the agreement between CE and ileocolonoscopy (IC) for determining the severity and classification of lesions in ileocolonic CD.<\/jats:p><jats:p>\n          Patients and methods\u2002In a prospective blinded multicenter study, patients with suspected CD were examined with CE and IC within 2 weeks. Ninety-nine participants with a full IC and CE were included in the analysis. The ileocolonic disease severity was assessed with the Simple Endoscopic Score for Crohn\u2019s Disease (SES-CD).<\/jats:p><jats:p>\n          Results\u2002CD was diagnosed in 30 patients with IC and CE. The mean SES-CD was 9.8 (CI 7.9\u201311.8) and 10.6 (CI 8.2\u201313.1), respectively (P\u200a=\u200a0.69). There was a substantial agreement (ICC 0.83, CI 0.68\u20130.92) and a strong correlation between SES-CD assessed with IC and CE (rs\u200a=\u200a0.78, P\u200a&lt;\u200a0.001). 55 bowel segments had ulcerations with both modalities (terminal ileum 24, right colon 12, transverse colon eight, left colon eight and rectum three). Mean sub-scores for ulcer size, area of ulcerated surface and area of affected surface did not differ between modalities. The inter-modality agreement (\u03ba) was 0.46, 0.34 and 0.43, respectively (P\u200a&lt;\u200a0.001). <\/jats:p><jats:p>\n          Conclusions\u2002There is a strong correlation between IC and CE for the severity of ileocolonic CD. The agreement for SES-CD sub-scores is fair to moderate. CE could be an alternative to IC for the assessment of endoscopic severity in selected patients with suspected CD.<\/jats:p>","DOI":"10.1055\/a-1978-6586","type":"journal-article","created":{"date-parts":[[2022,11,15]],"date-time":"2022-11-15T05:53:36Z","timestamp":1668491616000},"page":"E32-E38","source":"Crossref","is-referenced-by-count":9,"title":["Endoscopic severity and classification of lesions with pan-enteric capsule endoscopy and ileocolonoscopy in ileocolonic Crohn\u2019s disease"],"prefix":"10.1055","volume":"11","clinical-trial-number":[{"clinical-trial-number":"nct03134586","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Jacob Broder","family":"Brodersen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Section of Gastroenterology, Hospital of South West Jutland, Esbjerg, Denmark"},{"name":"Department of Regional Health Research, University of Southern Denmark, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens","family":"Kjeldsen","sequence":"additional","affiliation":[{"name":"Department of Medical Gastroenterology, Odense University Hospital, Odense, Denmark"},{"name":"Research Unit of Medical Gastroenterology, Department of Clinical Research, University of Southern Denmark, Odense, Denmark"},{"name":"OPEN Odense Patient data Explorative Network, Odense University Hospital, Odense, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Torben","family":"Knudsen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Section of Gastroenterology, Hospital of South West Jutland, Esbjerg, Denmark"},{"name":"Department of Regional Health Research, University of Southern Denmark, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael Dam","family":"Jensen","sequence":"additional","affiliation":[{"name":"Department of Regional Health Research, University of Southern Denmark, Denmark"},{"name":"Department of Internal Medicine, Section of Gastroenterology, Lillebaelt Hospital, Vejle, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,1,4]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1093\/ecco-jcc\/jjy113","article-title":"ECCO-ESGAR Guideline for Diagnostic Assessment in IBD Part 1: Initial diagnosis, monitoring of known IBD, detection of complications","volume":"13","author":"C Maaser","year":"2019","journal-title":"J Crohns Colitis"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.gie.2017.07.018","article-title":"Guidelines for sedation and anesthesia in GI endoscopy","volume":"87","author":"D S Early","year":"2018","journal-title":"Gastrointest Endosc"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/j.gie.2019.07.033","article-title":"ASGE review of 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