{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T15:22:40Z","timestamp":1790436160747,"version":"4.1.0"},"reference-count":30,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg K Kleintiere Heimtiere"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Gegenstand und Ziel Kaninchenschnupfen geh\u00f6rt zu den\n                    h\u00e4ufigsten Herausforderungen in der tier\u00e4rztlichen Praxis. Ziel\n                    der vorliegenden Ver\u00f6ffentlichung war die Auswertung eingesandter Proben\n                    aus Kaninchennasen (2015\u20132019) in Bezug auf Erregerverteilung und\n                    Antibiotikaresistenzen.<\/jats:p>\n                  <jats:p>Material und Methoden Jede Probe wurde auf 4 verschiedene Agarplatten\n                    ausgestrichen sowie in einer nicht selektiven Bouillon angereichert. Die\n                    Identifizierung der Bakterien erfolgte mittels MALDI\n                            Biotyper\n            \u00ae\n           (MBT) (Bruker Daltonik GmbH,\n                    Bremen, Deutschland) und die Antibiogrammerstellung mittels\n                    Bouillon-Mikrodilutionsmethode gem\u00e4\u00df Clinical and Laboratory\n                    Standards Institute (CLSI, Wayne, PA).<\/jats:p>\n                  <jats:p>Ergebnisse Ausgewertet wurden 1261 Proben. Bei den positiv befundeten\n                    Proben (n=941) wurde in 79,1% eine Bakterienspezies und in\n                    20,9% mehr als eine Bakterienspezies (Mischkultur) nachgewiesen.\n                    Insgesamt wurden 150 unterschiedliche Spezies aus 14 Bakterienfamilien\n                    differenziert. Vertreter der Pasteurellaceae wurden am h\u00e4ufigsten\n                    identifiziert, gefolgt von Enterobacteriaceae, Pseudomonadaceae\n                    und Staphylococcaceae.<\/jats:p>\n                  <jats:p>Ausgewertet wurden 467 Antibiogramme der am h\u00e4ufigsten nachgewiesenen\n                    Bakterien mit m\u00f6glicher klinischer Bedeutung (Pasteurella\n                        multocida [14,6%], Pasteurella spp. [10,0%],\n                        Staphylococcus aureus [5,9%], Pseudomonas aeruginosa\n                    [5,4%] und Bordetella bronchiseptica [4,8%]). Chinolone\n                    zeigten die gr\u00f6\u00dfte und Clindamycin die geringste Wirksamkeit.\n                    Weiterhin lag der h\u00f6chste Anteil von MRSA an S.\n                    aureus-Isolaten 2016 bei 23,1%.<\/jats:p>\n                  <jats:p>Schlussfolgerungen und klinische Relevanz Da die f\u00fcr\n                    Kaninchenschnupfen kausalen Bakterien meistens in den tieferen Bereichen der\n                    Nase vorzufinden sind und der Nasenvorhof h\u00e4ufig mit ubiquit\u00e4ren\n                    und coliformen Bakterien kontaminiert ist, w\u00e4re es sinnvoll, tiefe\n                    Nasentupferproben bzw. idealerweise Nasensp\u00fclproben zu entnehmen.\n                    Aufgrund der nachgewiesenen Erregervielfalt und einer mit der Erkrankung\n                    einhergehenden Langzeittherapie sollte im Rahmen der Behandlung ein Antibiogramm\n                    durchgef\u00fchrt werden. Liegt kein Antibiogramm vor, ist Enrofloxacin wegen\n                    seiner sehr guten Resistenzlage und Vertr\u00e4glichkeit Mittel der ersten\n                    Wahl. Da jedoch Chinolone als \u201ekritische\u201c Antibiotika eingestuft\n                    werden, sollte ihr Einsatz auf ein Minimum beschr\u00e4nkt werden.<\/jats:p>","DOI":"10.1055\/a-1989-1688","type":"journal-article","created":{"date-parts":[[2023,3,14]],"date-time":"2023-03-14T19:32:17Z","timestamp":1678822337000},"page":"22-35","source":"Crossref","is-referenced-by-count":4,"title":["Vorkommen und Resistenzen von Bakterien in Proben aus Kaninchennasen\n                    \u2013 eine retrospektive Auswertung"],"prefix":"10.1055","volume":"51","author":[{"given":"Cornelia","family":"Meyer","sequence":"additional","affiliation":[{"name":"SYNLAB.vet GmbH, Augsburg"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannes","family":"Maier","sequence":"additional","affiliation":[{"name":"SYNLAB.vet GmbH, Augsburg"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jutta","family":"Hein","sequence":"additional","affiliation":[{"name":"Tierarztpraxis Bergheim, Augsburg"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,3,14]]},"reference":[{"key":"ref1","first-page":"435","volume-title":"Chapter 14 Infectious diseases of domestic rabbits. 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